Publications by authors named "Brett D Lindenbach"

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SARS-CoV-2-related bat viruses evade human intrinsic immunity but lack efficient transmission capacity.
Mario A Peña-Hernández, Mia Madel Alfajaro, Renata B Filler, Miyu Moriyama, Emma L Keeler, Brett D Lindenbach

Nat Microbiol· August 2024

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Proof-of-concept studies with a computationally designed M inhibitor as a synergistic combination regimen alternative to Paxlovid.
Christina Papini, Irfan Ullah, Amalendu P Ranjan, Shuo Zhang, Qihao Wu, Brett D Lindenbach

Proc Natl Acad Sci U S A· April 2024

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Prior Influenza Infection Mitigates SARS-CoV-2 Disease in Syrian Hamsters.
Caterina Di Pietro, Ann M Haberman, Brett D Lindenbach, Peter C Smith, Emanuela M Bruscia

Viruses· February 2024

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Positive-strand RNA viruses-a Keystone Symposia report.
Jennifer Cable, Mark R Denison, Margaret Kielian, William T Jackson, Ralf Bartenschlager, Brett D Lindenbach

Ann N Y Acad Sci· March 2023

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Reinventing positive-strand RNA virus reverse genetics.
Brett D Lindenbach

Adv Virus Res· July 2022

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The and Architecture of the Hepatitis C Virus RNA Genome Uncovers Functional RNA Secondary and Tertiary Structures.
Han Wan, Rebecca L Adams, Brett D Lindenbach, Anna Marie Pyle

J Virol· April 2022

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Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency.
Chun-Hui Zhang, Krasimir A Spasov, Raquel A Reilly, Klarissa Hollander, Elizabeth A Stone, Brett D Lindenbach

ACS Med Chem Lett· August 2021

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Restriction of SARS-CoV-2 replication by targeting programmed -1 ribosomal frameshifting.
Yu Sun, Laura Abriola, Rachel O Niederer, Savannah F Pedersen, Mia M Alfajaro, Brett D Lindenbach

Proc Natl Acad Sci U S A· June 2021

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Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.
Jin Wei, Mia Madel Alfajaro, Peter C DeWeirdt, Ruth E Hanna, William J Lu-Culligan, Brett D Lindenbach

Cell· January 2021

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Restriction of SARS-CoV-2 Replication by Targeting Programmed -1 Ribosomal Frameshifting In Vitro.
Yu Sun, Laura Abriola, Yulia V Surovtseva, Brett D Lindenbach, Junjie U Guo

bioRxiv· October 2020

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Hepatitis C virus NS3-4A protease regulates the lipid environment for RNA replication by cleaving host enzyme 24-dehydrocholesterol reductase.
Lorillee Tallorin, Valerie A Villareal, Chih-Yun Hsia, Mary A Rodgers, Dominique J Burri, Brett D Lindenbach

J Biol Chem· August 2020

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A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating.
Harish N Ramanathan, Shuo Zhang, Florian Douam, Katrina B Mar, Jinhong Chang, Brett D Lindenbach

mBio· April 2020

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Screening effectors for antiviral effects reveals Rab1 GTPase as a proviral factor coopted for tombusvirus replication.
Jun-Ichi Inaba, Kai Xu, Nikolay Kovalev, Harish Ramanathan, Craig R Roy, Brett D Lindenbach

Proc Natl Acad Sci U S A· October 2019

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MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.
Sathish Kumar, Rina Barouch-Bentov, Fei Xiao, Stanford Schor, Szuyuan Pu, Brett D Lindenbach

Cell Rep· February 2019

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Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies.
Ralf Bartenschlager, Thomas F Baumert, Jens Bukh, Michael Houghton, Stanley M Lemon, Brett D Lindenbach

Virus Res· March 2018

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Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release.
Fei Xiao, Stanley Wang, Rina Barouch-Bentov, Gregory Neveu, Szuyuan Pu, Brett D Lindenbach

mBio· March 2018

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Recovery of Infectious Hepatitis C Virus From Injection Paraphernalia: Implications for Prevention Programs Serving People Who Inject Drugs.
Robert Heimer, Mawuena Binka, Stephen Koester, Jean-Paul C Grund, Amisha Patel, Brett D Lindenbach

J Infect Dis· January 2018

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IRE1α promotes viral infection by conferring resistance to apoptosis.
Susan L Fink, Teshika R Jayewickreme, Ryan D Molony, Takao Iwawaki, Charles S Landis, Brett D Lindenbach

Sci Signal· June 2017

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Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil.
Claire L Donald, Benjamin Brennan, Stephanie L Cumberworth, Veronica V Rezelj, Jordan J Clark, Brett D Lindenbach

PLoS Negl Trop Dis· October 2016

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Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia.
Marco Onorati, Zhen Li, Fuchen Liu, André M M Sousa, Naoki Nakagawa, Brett D Lindenbach

Cell Rep· September 2016

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Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection.
Laura J Yockey, Luis Varela, Tasfia Rakib, William Khoury-Hanold, Susan L Fink, Brett D Lindenbach

Cell· August 2016

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Zika virus productively infects primary human placenta-specific macrophages.
Kellie Ann Jurado, Michael K Simoni, Zhonghua Tang, Ryuta Uraki, Jesse Hwang, Brett D Lindenbach

JCI Insight· August 2016

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What's next for hepatitis C virus research?
Brett D Lindenbach

Hepatology· May 2016

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The Coding Region of the HCV Genome Contains a Network of Regulatory RNA Structures.
Nathan Pirakitikulr, Andrew Kohlway, Brett D Lindenbach, Anna M Pyle

Mol Cell· April 2016

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Correction: A Conserved NS3 Surface Patch Orchestrates NS2 Protease Stimulation, NS5A Hyperphosphorylation and HCV Genome Replication.
Olaf Isken, Ulrike Langerwisch, Vlastimil Jirasko, Dirk Rehders, Lars Redecke, Brett D Lindenbach

PLoS Pathog· January 2016

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