Publications by authors named "Brett Jorgensen"

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TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL.
Harbani K Malik-Chaudhry, Kirthana Prabhakar, Harshad S Ugamraj, Andrew A Boudreau, Benjamin Buelow, Brett Jorgensen

MAbs· January 2022

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Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies.
Nathan D Trinklein, Duy Pham, Ute Schellenberger, Ben Buelow, Andrew Boudreau, Brett Jorgensen

MAbs· January 2020

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Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies.
Starlynn C Clarke, Biao Ma, Nathan D Trinklein, Ute Schellenberger, Michael J Osborn, Brett Jorgensen

Front Immunol· October 2019

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Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies.
Katherine E Harris, Shelley Force Aldred, Laura M Davison, Heather Anne N Ogana, Andrew Boudreau, Brett Jorgensen

Front Immunol· July 2019

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PEGylated IL-10 Activates Kupffer Cells to Control Hypercholesterolemia.
Ivan H Chan, Dennis Van Hoof, Marina Abramova, Melissa Bilardello, Elliot Mar, Brett Jorgensen

PLoS One· July 2017

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Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer.
Derek C Marshall, Susan K Lyman, Scott McCauley, Maria Kovalenko, Rhyannon Spangler, Brett Jorgensen

PLoS One· April 2016

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Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment.
Vivian Barry-Hamilton, Rhyannon Spangler, Derek Marshall, Scott McCauley, Hector M Rodriguez, Brett Jorgensen

Nat Med· September 2010

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Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.
Pei Jin, Juan Zhang, Percy F Sumariwalla, Irene Ni, Brett Jorgensen

Arthritis Res Ther· February 2009

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Rational optimization of a bispecific ligand trap targeting EGF receptor family ligands.
Pei Jin, Juan Zhang, Malgorzata Beryt, Lisa Turin, Cathleen Brdlik, Brett Jorgensen

Mol Med· February 2009

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Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts.
Jay Sarup, Pei Jin, Lisa Turin, Xiaomei Bai, Malgorzata Beryt, Brett Jorgensen

Mol Cancer Ther· October 2008

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