Publications by authors named "Brian A Dougherty"

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Comprehensive comparison of enzymatic and bisulfite DNA methylation analysis in clinically relevant samples.
Barrett Nuttall, Daniel L Karl, Kathleen Burke, Megan Callahan, Kerrin Mendler, Brian A Dougherty

Clin Epigenetics· October 2025

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Somatic BRCA1/2 mutations are associated with a similar survival advantage to their germline counterparts in tubo-ovarian high grade serous carcinoma.
Robert L Hollis, Michael Churchman, Graeme R Grimes, Alison M Meynert, Philippe Gautier, Brian A Dougherty

Eur J Cancer· March 2025

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Concordance of BRCA mutation detection in tumor versus blood, and frequency of bi-allelic loss of BRCA in tumors from patients in the phase III SOLO2 trial.
Darren R Hodgson, Jessica S Brown, Simon P Dearden, Zhongwu Lai, Cathy E Elks, Brian A Dougherty

Gynecol Oncol· December 2021

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A phase 1/2 study of the combination of acalabrutinib and vistusertib in patients with relapsed/refractory B-cell malignancies.
Graham P Collins, Tracy N Clevenger, Kathleen A Burke, Buyue Yang, Alex MacDonald, Brian A Dougherty

Leuk Lymphoma· November 2021

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Orthogonal Comparison of Four Plasma NGS Tests With Tumor Suggests Technical Factors are a Major Source of Assay Discordance.
Daniel Stetson, Ambar Ahmed, Xing Xu, Barrett R B Nuttall, Tristan J Lubinski, Brian A Dougherty

JCO Precis Oncol· December 2019

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Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes.
Darren R Hodgson, Brian A Dougherty, Zhongwu Lai, Anitra Fielding, Lynda Grinsted

Br J Cancer· November 2018

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Generation of stable PDX derived cell lines using conditional reprogramming.
Alexandra Borodovsky, Travis J McQuiston, Daniel Stetson, Ambar Ahmed, David Whitston, Brian A Dougherty

Mol Cancer· December 2017

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Long-Term Responders on Olaparib Maintenance in High-Grade Serous Ovarian Cancer: Clinical and Molecular Characterization.
Stephanie Lheureux, Zhongwu Lai, Brian A Dougherty, Sarah Runswick, Darren R Hodgson

Clin Cancer Res· August 2017

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Biological and clinical evidence for somatic mutations in BRCA1 and BRCA2 as predictive markers for olaparib response in high-grade serous ovarian cancers in the maintenance setting.
Brian A Dougherty, Zhongwu Lai, Darren R Hodgson, Maria C M Orr, Matthew Hawryluk

Oncotarget· July 2017

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Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital.
Thomas D Gootz, Mary Kay Lescoe, Fadia Dib-Hajj, Brian A Dougherty, Wen He

Antimicrob Agents Chemother· May 2009

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Conserved fungal genes as potential targets for broad-spectrum antifungal drug discovery.
Mengping Liu, Matthew D Healy, Brian A Dougherty, Kim M Esposito, Trina C Maurice

Eukaryot Cell· April 2006

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Purification, cloning, and functional expression of phenylalanine aminomutase: the first committed step in Taxol side-chain biosynthesis.
Christopher L Steele, Yijun Chen, Brian A Dougherty, Wenying Li, Sandra Hofstead

Arch Biochem Biophys· June 2005

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Structural and functional characterization of CFE88: evidence that a conserved and essential bacterial protein is a methyltransferase.
Keith L Constantine, Stanley R Krystek, Matthew D Healy, Michael L Doyle, Nathan O Siemers, Brian A Dougherty

Protein Sci· June 2005

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Decrypting the biochemical function of an essential gene from Streptococcus pneumoniae using ThermoFluor technology.
Theodore E Carver, Brian Bordeau, Maxwell D Cummings, Eugene C Petrella, Michael J Pucci, Brian A Dougherty

J Biol Chem· March 2005

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Random chromosomal gene disruption using cassette mutagenesis.
French A Lewis, Brian A Dougherty

Methods Mol Biol· May 2002

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Identification of Haemophilus influenzae Rd transformation genes using cassette mutagenesis.
Brian A Dougherty, Hamilton O Smith

Microbiology (Reading)· February 1999

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