Publications by authors named "Brian Abraham"

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Generation of an iPSC-derived alveolar rhabdomyosarcoma cell line during directed endothelial differentiation.
Randolph K Larsen, Madeline B Searcy, Bradley T Stevens, Katherine E Gadek, Yang Zhang, Brian J Abraham

Stem Cell Res· December 2025

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KAT6A/B inhibition synergizes with retinoic acid and enhances the efficacy of GD2-targeted immunotherapy in neuroblastoma.
Nina Weichert-Leahey, Alla Berezovskaya, Mark W Zimmerman, Francesca Alvarez-Calderon, Marlana Winschel, Brian J Abraham

bioRxiv· July 2025

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Specific oncogene activation of the cell of origin in mucosal melanoma.
Swathy Babu, Jiajia Chen, Chloé S Baron, Kaiwen Sun, Emily Robitschek, Brian J Abraham

Nat Commun· July 2025

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Multitargeted Reduction of Inflammation and Atherosclerosis in -deficient CHIP via XPO1 Inhibition and Atf3 restoration.
Nicole Prutsch, Amélie Vromman, Brittaney Leeper, Mengyu Chen, Julia Keating, Brian J Abraham

bioRxiv· June 2025

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Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid.
Min Pan, Yinwen Zhang, William C Wright, Xueying Liu, Barbara Passaia, Brian J Abraham

Nat Commun· February 2025

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Accurate Measurement of Cell Number-Normalized Differential Gene Expression in Cells Treated With Retinoic Acid.
Nina Weichert-Leahey, Mark W Zimmerman, Alla Berezovskaya, A Thomas Look, Brian J Abraham

Bio Protoc· November 2024

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Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid.
Min Pan, Yinwen Zhang, William C Wright, Xueying Liu, Barbara Passaia, Brian J Abraham

bioRxiv· May 2024

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Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Noha A M Shendy, Melissa Bikowitz, Logan H Sigua, Yang Zhang, Audrey Mercier, Brian J Abraham

Nat Commun· April 2024

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Specific oncogene activation of the cell of origin in mucosal melanoma.
Swathy Babu, Jiajia Chen, Emily Robitschek, Chloé S Baron, Alicia McConnell, Brian J Abraham

bioRxiv· April 2024

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STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma.
Nicole Prutsch, Shuning He, Alla Berezovskaya, Adam D Durbin, Neekesh V Dharia, Brian J Abraham

Cell Rep Med· March 2024

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PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors.
Madeline B Searcy, Randolph K Larsen, Bradley T Stevens, Yang Zhang, Hongjian Jin, Brian J Abraham

Nat Commun· November 2023

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Regulatory architecture of housekeeping genes is driven by promoter assemblies.
Marion Dejosez, Alessandra Dall'Agnese, Mahesh Ramamoorthy, Jesse Platt, Xing Yin, Abraham S Weintraub, Brian J Abraham

Cell Rep· May 2023

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Genetic predisposition to neuroblastoma results from a regulatory polymorphism that promotes the adrenergic cell state.
Nina Weichert-Leahey, Hui Shi, Ting Tao, Derek A Oldridge, Adam D Durbin, Brian J Abraham

J Clin Invest· May 2023

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Oncogenic mutations impede nuclear RNA surveillance.
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust

Science· April 2023

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Genetic Predisposition to Neuroblastoma Results from a Regulatory Polymorphism that Promotes the Adrenergic Cell State.
Nina Weichert-Leahey, Hui Shi, Ting Tao, Derek A Oldridge, Adam D Durbin, Brian J Abraham

bioRxiv· March 2023

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The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes.
Haiting Ma, Esmée de Zwaan, Yang Eric Guo, Paloma Cejas, Prathapan Thiru, Brian J Abraham

Cell Stem Cell· November 2022

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BRD2 interconnects with BRD3 to facilitate Pol II transcription initiation and elongation to prime promoters for cell differentiation.
Chenlu Wang, Qiqin Xu, Xianhong Zhang, Daniel S Day, Brian J Abraham

Cell Mol Life Sci· June 2022

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The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes.
Haiting Ma, Esmée de Zwaan, Yang Eric Guo, Paloma Cejas, Prathapan Thiru, Brian J Abraham

Cell Stem Cell· May 2022

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Intrinsic transcriptional heterogeneity in neuroblastoma guides mechanistic and therapeutic insights.
Noha A M Shendy, Mark W Zimmerman, Brian J Abraham, Adam D Durbin

Cell Rep Med· May 2022

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EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma.
Adam D Durbin, Tingjian Wang, Virangika K Wimalasena, Mark W Zimmerman, Deyao Li, Brian J Abraham

Cancer Discov· March 2022

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SEAseq: a portable and cloud-based chromatin occupancy analysis suite.
Modupeore O Adetunji, Brian J Abraham

BMC Bioinformatics· February 2022

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Synergistic Anti-Tumor Effect of Combining Selective CDK7 and BRD4 Inhibition in Neuroblastoma.
Yang Gao, Marina Volegova, Nicole Nasholm, Sanjukta Das, Nicholas Kwiatkowski, Brian J Abraham

Front Oncol· January 2022

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Predicting master transcription factors from pan-cancer expression data.
Jessica Reddy, Marcos A S Fonseca, Rosario I Corona, Robbin Nameki, Felipe Segato Dezem, Brian J Abraham

Sci Adv· November 2021

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Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma.
Mark W Zimmerman, Adam D Durbin, Shuning He, Felix Oppel, Hui Shi, Brian J Abraham

Sci Adv· October 2021

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MEIS2 Is an Adrenergic Core Regulatory Transcription Factor Involved in Early Initiation of TH-MYCN-Driven Neuroblastoma Formation.
Jolien De Wyn, Mark W Zimmerman, Nina Weichert-Leahey, Carolina Nunes, Belamy B Cheung, Brian J Abraham

Cancers (Basel)· September 2021

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