Publications by authors named "Adam D Durbin"

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EP300 deficiency leads to chronic replication stress mediated by defective replication fork protection.
Angelica Barreto-Galvez, Mrunmai Niljikar, Julia Elizabeth Gagliardi, Carolina Plasencia Guzman, Ranran Zhang, Adam David Durbin

Nat Commun· December 2025

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KAT6A/B inhibition synergizes with retinoic acid and enhances the efficacy of GD2-targeted immunotherapy in neuroblastoma.
Nina Weichert-Leahey, Alla Berezovskaya, Mark W Zimmerman, Francesca Alvarez-Calderon, Marlana Winschel, Adam D Durbin

bioRxiv· July 2025

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Lineage-Selective Dependencies in Pediatric Cancers.
K Elaine Ritter, Adam D Durbin

Cold Spring Harb Perspect Med· April 2025

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Insights on Future Directions in Cancer Research from the 2025 AACR NextGen Stars.
Edmond M Chan, Yash Chhabra, Karen O Dixon, Adam D Durbin, Anniina Färkkilä

Cancer Discov· April 2025

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Myogenesis gone awry: the role of developmental pathways in rhabdomyosarcoma.
Annika L Gustafson, Adam D Durbin, Kristin B Artinger, Heide L Ford

Front Cell Dev Biol· January 2025

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Cell state plasticity in neuroblastoma.
Adam D Durbin, Rogier Versteeg

EJC Paediatr Oncol· December 2024

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Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Noha A M Shendy, Melissa Bikowitz, Logan H Sigua, Yang Zhang, Audrey Mercier, Adam D Durbin

Nat Commun· April 2024

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STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma.
Nicole Prutsch, Shuning He, Alla Berezovskaya, Adam D Durbin, Neekesh V Dharia

Cell Rep Med· March 2024

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Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma.
Ahmed Abu-Zaid, Jie Fang, Hongjian Jin, Shivendra Singh, Prahalathan Pichavaram, Adam D Durbin

Cell Rep Med· March 2024

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PRMT5 orchestrates EGFR and AKT networks to activate NFκB and promote EMT.
Lei Huang, Manasa Ravi, Xiao-Ou Zhang, Odette Verdejo-Torres, Noha A M Shendy, Adam D Durbin

bioRxiv· January 2024

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A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics.
Hyeong-Min Lee, William C Wright, Min Pan, Jonathan Low, Duane Currier, Adam D Durbin

Nat Commun· November 2023

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Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities.
Yuxiang Zhang, David Remillard, Ugoma Onubogu, Barbara Karakyriakou, Joshua N Asiaban, Adam D Durbin

Nat Struct Mol Biol· August 2023

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Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma.
Jie Fang, Shivendra Singh, Changde Cheng, Sivaraman Natarajan, Heather Sheppard, Adam D Durbin

Nat Commun· July 2023

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Genetic predisposition to neuroblastoma results from a regulatory polymorphism that promotes the adrenergic cell state.
Nina Weichert-Leahey, Hui Shi, Ting Tao, Derek A Oldridge, Adam D Durbin

J Clin Invest· May 2023

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Genetic Predisposition to Neuroblastoma Results from a Regulatory Polymorphism that Promotes the Adrenergic Cell State.
Nina Weichert-Leahey, Hui Shi, Ting Tao, Derek A Oldridge, Adam D Durbin

bioRxiv· March 2023

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Retraction Notice to: Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2.
Ken Morita, Shuning He, Radosław P Nowak, Jinhua Wang, Mark W Zimmerman, Adam D Durbin

Cell· August 2022

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Intrinsic transcriptional heterogeneity in neuroblastoma guides mechanistic and therapeutic insights.
Noha A M Shendy, Mark W Zimmerman, Brian J Abraham, Adam D Durbin

Cell Rep Med· May 2022

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EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma.
Adam D Durbin, Tingjian Wang, Virangika K Wimalasena, Mark W Zimmerman, Deyao Li

Cancer Discov· March 2022

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SIX1 reprograms myogenic transcription factors to maintain the rhabdomyosarcoma undifferentiated state.
Jessica Y Hsu, Etienne P Danis, Stephanie Nance, Jenean H O'Brien, Annika L Gustafson, Adam D Durbin

Cell Rep· February 2022

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Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma.
Mark W Zimmerman, Adam D Durbin, Shuning He, Felix Oppel, Hui Shi

Sci Adv· October 2021

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MEIS2 Is an Adrenergic Core Regulatory Transcription Factor Involved in Early Initiation of TH-MYCN-Driven Neuroblastoma Formation.
Jolien De Wyn, Mark W Zimmerman, Nina Weichert-Leahey, Carolina Nunes, Belamy B Cheung, Adam D Durbin

Cancers (Basel)· September 2021

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Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.
Hiroto Ohguchi, Paul M C Park, Tingjian Wang, Berkley E Gryder, Daisuke Ogiya, Adam D Durbin

Blood Cancer Discov· July 2021

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Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Jasper E Neggers, Brenton R Paolella, Adhana Asfaw, Michael V Rothberg, Thomas A Skipper, Adam D Durbin

Cell Rep· July 2021

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A Resident-Led Virtual Journal Club to Educate Pediatric Residents About Coronavirus Disease 2019.
Milad Rezvani, Geoffrey A Smith, Joseph A Majzoub, Adam D Durbin, Ariel S Winn

Acad Pediatr· June 2021

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A first-generation pediatric cancer dependency map.
Neekesh V Dharia, Guillaume Kugener, Lillian M Guenther, Clare F Malone, Adam D Durbin

Nat Genet· April 2021

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