Publications by authors named "Rogier Versteeg"

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The USP11/TCEAL1 complex promotes transcription elongation to sustain oncogenic gene expression in neuroblastoma.
Markus Dehmer, Katrin Trunk, Peter Gallant, Daniel Fleischhauer, Mareike Müller, Rogier Versteeg

Genes Dev· June 2025

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Cell state plasticity in neuroblastoma.
Adam D Durbin, Rogier Versteeg

EJC Paediatr Oncol· December 2024

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FOXO3A-short is a novel regulator of non-oxidative glucose metabolism associated with human longevity.
Evan E Santo, Rasmus Ribel-Madsen, Peter J Stroeken, Vincent C J de Boer, Ninna S Hansen, Rogier Versteeg

Aging Cell· March 2023

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SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry.
Bieke Decaesteker, Amber Louwagie, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Rogier Versteeg

Nat Commun· March 2023

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MEK inhibition causes BIM stabilization and increased sensitivity to BCL-2 family member inhibitors in RAS-MAPK-mutated neuroblastoma.
Thomas F Eleveld, Lindy Vernooij, Linda Schild, Bianca Koopmans, Lindy K Alles, Rogier Versteeg

Front Oncol· February 2023

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Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes.
Satyaki Sengupta, Sanjukta Das, Angela C Crespo, Annelisa M Cornel, Anand G Patel, Rogier Versteeg

Nat Cancer· October 2022

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DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma.
Thale Kristin Olsen, Cecilia Dyberg, Bethel Tesfai Embaie, Adele Alchahin, Jelena Milosevic, Rogier Versteeg

JCI Insight· August 2022

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Correction: Mesenchymal-Type Neuroblastoma Cells Escape ALK Inhibitors.
Ellen M Westerhout, Mohamed Hamdi, Peter Stroeken, Natalia E Nowakowska, Arjan Lakeman, Rogier Versteeg

Cancer Res· July 2022

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Mesenchymal-Type Neuroblastoma Cells Escape ALK Inhibitors.
Ellen M Westerhout, Mohamed Hamdi, Peter Stroeken, Natalia E Nowakowska, Arjan Lakeman, Rogier Versteeg

Cancer Res· February 2022

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Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma.
Marlinde L van den Boogaard, Rurika Oka, Anne Hakkert, Linda Schild, Marli E Ebus, Rogier Versteeg

Proc Natl Acad Sci U S A· September 2021

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A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma.
Laura D Gamble, Stefania Purgato, Michelle J Henderson, Simone Di Giacomo, Amanda J Russell, Rogier Versteeg

Cancers (Basel)· April 2021

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Super enhancers define regulatory subtypes and cell identity in neuroblastoma.
Moritz Gartlgruber, Ashwini Kumar Sharma, Andrés Quintero, Daniel Dreidax, Selina Jansky, Rogier Versteeg

Nat Cancer· January 2021

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A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities.
Ravi S Narayan, Piet Molenaar, Jian Teng, Fleur M G Cornelissen, Irene Roelofs, Rogier Versteeg

Nat Commun· June 2020

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Mesenchymal Neuroblastoma Cells Are Undetected by Current mRNA Marker Panels: The Development of a Specific Neuroblastoma Mesenchymal Minimal Residual Disease Panel.
Esther M van Wezel, Lieke M J van Zogchel, Jalenka van Wijk, Ilse Timmerman, Ngoc-Kim Vo, Rogier Versteeg

JCO Precis Oncol· October 2019

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ALK positively regulates MYCN activity through repression of HBP1 expression.
Shana Claeys, Geertrui Denecker, Kaat Durinck, Bieke Decaesteker, Liselot M Mus, Rogier Versteeg

Oncogene· April 2019

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A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma.
Tim van Groningen, Nurdan Akogul, Ellen M Westerhout, Alvin Chan, Nancy E Hasselt, Rogier Versteeg

Nat Commun· April 2019

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Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase.
Steffi Herold, Jacqueline Kalb, Gabriele Büchel, Carsten P Ade, Apoorva Baluapuri, Rogier Versteeg

Nature· March 2019

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RAS-MAPK Pathway-Driven Tumor Progression Is Associated with Loss of CIC and Other Genomic Aberrations in Neuroblastoma.
Thomas F Eleveld, Linda Schild, Jan Koster, Danny A Zwijnenburg, Lindy K Alles, Rogier Versteeg

Cancer Res· November 2018

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TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
Bieke Decaesteker, Geertrui Denecker, Christophe Van Neste, Emmy M Dolman, Wouter Van Loocke, Rogier Versteeg

Nat Commun· November 2018

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Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients.
Pauline Depuydt, Valentina Boeva, Toby D Hocking, Robrecht Cannoodt, Inge M Ambros, Rogier Versteeg

J Natl Cancer Inst· October 2018

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Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma.
Presha Rajbhandari, Gonzalo Lopez, Claudia Capdevila, Beatrice Salvatori, Jiyang Yu, Rogier Versteeg

Cancer Discov· May 2018

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Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response.
B Florien Westendorp, Nikè V J A Büller, Olga N Karpus, Willemijn A van Dop, Jan Koster, Rogier Versteeg

Cell Mol Gastroenterol Hepatol· September 2017

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Neuroblastoma is composed of two super-enhancer-associated differentiation states.
Tim van Groningen, Jan Koster, Linda J Valentijn, Danny A Zwijnenburg, Nurdan Akogul, Rogier Versteeg

Nat Genet· August 2017

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Enhancer of zeste homologue 2 plays an important role in neuroblastoma cell survival independent of its histone methyltransferase activity.
Laurel T Bate-Eya, Hinco J Gierman, Marli E Ebus, Jan Koster, Huib N Caron, Rogier Versteeg

Eur J Cancer· April 2017

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Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.
Elisa Matas-Rico, Michiel van Veen, Daniela Leyton-Puig, Jeroen van den Berg, Jan Koster, Rogier Versteeg

Cancer Cell· December 2016

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