Publications by authors named "Brian Angus"

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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
Merryn Voysey, Sue Ann Costa Clemens, Shabir A Madhi, Lily Y Weckx, Pedro M Folegatti, Parvinder K Aley, Brian Angus, Vicky L Baillie, Shaun L Barnabas, Qasim E Bhorat

Lancet· January 2021

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It never rains but pours: disseminated nocardiosis in a renal transplant patient from Nigeria - a case report.
Thomas Whitehead, Hein Zin Zaw, Ivo Elliott, Maisie-Jane Fry, Katie Jeffery, Brian J Angus

BMC Infect Dis· December 2025

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Safety, Efficacy, and Immunogenicity of a Salmonella Paratyphi A Vaccine.
Naina McCann, Margarete Paganotti Vicentine, Narges Ebrahimi, Melanie Greenland, Brian Angus

N Engl J Med· October 2025

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T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination.
Ji-Li Chen, Beibei Wang, Yongxu Lu, Elie Antoun, Olivia Bird, Brian Angus

Nat Commun· May 2025

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R21 in Matrix-M adjuvant in UK malaria-naive adult men and non-pregnant women aged 18-45 years: an open-label, partially blinded, phase 1-2a controlled human malaria infection study.
Navin Venkatraman, Daniel Silman, Duncan Bellamy, Lisa Stockdale, Georgina Bowyer, Brian Angus

Lancet Microbe· March 2025

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Evaluation of a novel malaria anti-sporozoite vaccine candidate, R21 in Matrix-M adjuvant, in the UK and Burkina Faso: two phase 1, first-in-human trials.
Navin Venkatraman, Alfred B Tiono, Georgina Bowyer, Duncan G Bellamy, Lisa K Stockdale, Brian Angus

Lancet Microbe· March 2025

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MAVMET trial: maraviroc and/or metformin for metabolic dysfunction associated fatty liver disease in adults with suppressed HIV.
Leanne McCabe, James E Burns, Arash Latifoltojar, Frank A Post, Julie Fox, Brian Angus

AIDS· August 2024

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Anomalies in the review process and interpretation of the evidence in the NICE guideline for chronic fatigue syndrome and myalgic encephalomyelitis.
Peter White, Susan Abbey, Brian Angus, Harriet A Ball, Dedra S Buchwald

J Neurol Neurosurg Psychiatry· December 2023

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Understanding the treatment benefit of hyperimmune anti-influenza intravenous immunoglobulin (Flu-IVIG) for severe human influenza.
Hillary A Vanderven, Deborah N Wentworth, Win Min Han, Heidi Peck, Ian G Barr, Brian Angus

JCI Insight· July 2023

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Accelerating clinical development of a live attenuated vaccine against Paratyphi A (VASP): study protocol for an observer-participant-blind randomised control trial of a novel oral vaccine using a human challenge model of Paratyphi A infection in healthy adult volunteers.
Naina McCann, Katherine Emary, Nisha Singh, Florence Mclean, Susana Camara, Brian Angus

BMJ Open· May 2023

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Malaria patient spectrum representation in therapeutic clinical trials of uncomplicated malaria: a scoping review of the literature.
Lorenzo Arena, Mazvita Zanamwe, Christine M Halleux, Verena Carrara, Brian J Angus

Malar J· February 2023

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Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever.
Rosângela Salerno-Gonçalves, Stephanie Fresnay, Laurence Magder, Thomas C Darton, Claire S Waddington, Brian Angus

Cell Immunol· August 2022

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Neurochemical abnormalities in chronic fatigue syndrome: a pilot magnetic resonance spectroscopy study at 7 Tesla.
Beata R Godlewska, Stephen Williams, Uzay E Emir, Chi Chen, Ann L Sharpley, Brian Angus

Psychopharmacology (Berl)· January 2022

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Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial.
Maheshi N Ramasamy, Angela M Minassian, Katie J Ewer, Amy L Flaxman, Pedro M Folegatti, Brian Angus

Lancet· December 2021

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Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002).
Amy Flaxman, Natalie G Marchevsky, Daniel Jenkin, Jeremy Aboagye, Parvinder K Aley, Brian Angus

Lancet· September 2021

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Author Correction: Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses.
Jordan R Barrett, Sandra Belij-Rammerstorfer, Christina Dold, Katie J Ewer, Pedro M Folegatti, Brian Angus

Nat Med· June 2021

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Author Correction: T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial.
Katie J Ewer, Jordan R Barrett, Sandra Belij-Rammerstorfer, Hannah Sharpe, Rebecca Makinson, Brian Angus

Nat Med· June 2021

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Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial.
Katherine R W Emary, Tanya Golubchik, Parvinder K Aley, Cristina V Ariani, Brian Angus

Lancet· April 2021

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Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.
Merryn Voysey, Sue Ann Costa Clemens, Shabir A Madhi, Lily Y Weckx, Pedro M Folegatti, Brian Angus

Lancet· March 2021

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Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses.
Jordan R Barrett, Sandra Belij-Rammerstorfer, Christina Dold, Katie J Ewer, Pedro M Folegatti, Brian Angus

Nat Med· February 2021

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T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial.
Katie J Ewer, Jordan R Barrett, Sandra Belij-Rammerstorfer, Hannah Sharpe, Rebecca Makinson, Brian Angus

Nat Med· February 2021

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Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge.
Betty Raman, Mark Philip Cassar, Elizabeth M Tunnicliffe, Nicola Filippini, Ludovica Griffanti, Brian J Angus

EClinicalMedicine· January 2021

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Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model.
Malick M Gibani, Celina Jin, Sonu Shrestha, Maria Moore, Lily Norman, Brian Angus

PLoS Negl Trop Dis· October 2020

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Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial.
Pedro M Folegatti, Katie J Ewer, Parvinder K Aley, Brian Angus, Stephan Becker

Lancet· August 2020

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An evaluation of rectal artesunate for the pre-hospital management of severe malaria.
Brian John Angus

Expert Opin Pharmacother· April 2020

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