Publications by authors named "Brian Chapron"

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Recent advances in the ontogeny of drug disposition.
Brian D Chapron, Alenka Chapron, J Steven Leeder

Br J Clin Pharmacol· October 2022

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Effect of Crohn's Disease on Villous Length and CYP3A4 Expression in the Pediatric Small Intestine.
Carrie A Vyhlidal, Brian D Chapron, Atif Ahmed, Vivekanand Singh, Rebecca Casini

Clin Transl Sci· March 2021

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The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites.
Brian D Chapron, Jean C Dinh, Paul C Toren, Andrea Gaedigk, J Steven Leeder

Drug Metab Dispos· November 2020

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An Improved Vascularized, Dual-Channel Microphysiological System Facilitates Modeling of Proximal Tubular Solute Secretion.
Alenka Chapron, Brian D Chapron, Dale W Hailey, Shih-Yu Chang, Tomoki Imaoka

ACS Pharmacol Transl Sci· June 2020

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Reevaluating the role of megalin in renal vitamin D homeostasis using a human cell-derived microphysiological system.
Brian D Chapron, Alenka Chapron, Brian Phillips, Miracle C Okoli, Danny D Shen

ALTEX· February 2019

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Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D-3--Sulfate, a Major Circulating Vitamin D Metabolite in Humans.
Timothy Wong, Zhican Wang, Brian D Chapron, Mizuki Suzuki, Katrina G Claw, Alenka Chapron

Drug Metab Dispos· April 2018

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Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity.
Shih-Yu Chang, Jenna L Voellinger, Kirk P Van Ness, Brian Chapron, Rachel M Shaffer

Toxicol In Vitro· April 2017

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Development of a microphysiological model of human kidney proximal tubule function.
Elijah J Weber, Alenka Chapron, Brian D Chapron, Jenna L Voellinger, Kevin A Lidberg

Kidney Int· September 2016

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Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism.
Yoshiyuki Yamaura, Brian D Chapron, Zhican Wang, Jonathan Himmelfarb, Kenneth E Thummel

Drug Metab Dispos· March 2016

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Reversible, time-dependent inhibition of CYP3A-mediated metabolism of midazolam and tacrolimus by telaprevir in human liver microsomes.
Brian Chapron, Linda Risler, Brian Phillips, Carol Collins, Kenneth Thummel

J Pharm Pharm Sci· January 2016

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