Publications by authors named "Brian D Brown"

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Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference.
Fereshteh Talebi, Fabiana Gregucci, Jalal Ahmed, Nir Ben Chetrit, Brian D Brown

Oncoimmunology· December 2025

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Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours.
Samarth Hegde, Bruno Giotti, Brian Y Soong, Laszlo Halasz, Jessica Le Berichel, Brian D Brown

Nature· October 2025

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Targeting and tracking mRNA lipid nanoparticles at the particle, transcript and protein level.
Diana D Kang, Adam Marks, Judit Morla-Folch, Yizhou Dong, Brian D Brown

Nat Biomed Eng· October 2025

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Potentiating CAR-T bystander killing by enhanced Fas/FasL signaling mitigates antigen escape in heterogeneous tumors.
Matthew J Lin, Joanna K Chorazeczewski, Gvantsa Pantsulaia, Alan Cooper, Moah Sohn, Brian D Brown

bioRxiv· September 2025

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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1CD8 T cells.
Etienne Humblin, Isabel Korpas, Nataliya Prokhnevska, Abishek Vaidya, Dan Filipescu, Brian D Brown

Immunity· August 2025

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Targeted Therapy of CAR+ T-Cell Lymphoma after Anti-BCMA CAR T-Cell Therapy.
Adolfo Aleman, Oliver Van Oekelen, David T Melnekoff, Leah Grossman, Tarek H Mouhieddine, Brian D Brown

N Engl J Med· August 2025

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Cancer vaccines and the future of immunotherapy.
Orrin Pail, Matthew J Lin, Theodora Anagnostou, Brian D Brown, Joshua D Brody

Lancet· July 2025

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Enhancing antitumor immunity through chemotherapeutic-derived lipid nanoparticle-induced immunogenic cell death and CD40L/Flt3L mRNA-mediated dendritic cell activation.
Xucheng Hou, Chang Wang, Yichen Zhong, Leiming Wang, Diana D Kang, Brian D Brown

J Control Release· June 2025

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Plasminogen activator inhibitors orchestrate the immunosuppressive tumor microenvironment in pancreatic cancer.
Chiara Falcomatà, Sebastian R Nielsen, Maximilian M Schaefer, Bhavya Singh, Alexander Tepper, Brian D Brown

bioRxiv· June 2025

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LNP-RNA-mediated antigen presentation leverages SARS-CoV-2-specific immunity for cancer treatment.
Yonger Xue, Xucheng Hou, Yichen Zhong, Yuebao Zhang, Shi Du, Brian D Brown

Nat Commun· March 2025

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Cholesterol mobilization regulates dendritic cell maturation and the immunogenic response to cancer.
Meriem Belabed, Matthew D Park, Cédric M Blouin, Sreekumar Balan, Chang Y Moon, Brian D Brown

Nat Immunol· February 2025

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Spatial genomics uncovers cytokines promoting ovarian tumour heterogeneity and immunotherapy resistance.
Gurkan Mollaoglu, Brian D Brown, Alessia Baccarini

Clin Transl Med· February 2025

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Ovarian cancer-derived IL-4 promotes immunotherapy resistance.
Gurkan Mollaoglu, Alexander Tepper, Chiara Falcomatà, Hunter T Potak, Luisanna Pia, Lindsay Browning, Brian D Brown

Cell· December 2024

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Unveiling the hidden network of STING's subcellular regulation.
Xiaoqi Sun, Brian D Brown

Cell Syst· December 2024

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Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoid structures in cancer.
Raphaël Mattiuz, Jesse Boumelha, Pauline Hamon, Jessica Le Berichel, Abishek Vaidya, Brian D Brown

bioRxiv· December 2024

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Bispecific antibody targeting of lipid nanoparticles.
Angelo Amabile, Matthew Phelan, Zhixin Yu, Pedro Silva, Adam Marks, Brian D Brown

bioRxiv· December 2024

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Hematopoietic aging promotes cancer by fueling IL-1⍺-driven emergency myelopoiesis.
Matthew D Park, Jessica Le Berichel, Pauline Hamon, C Matthias Wilk, Meriem Belabed, Brian D Brown

Science· October 2024

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ICOS limits memory-like properties and function of exhausted PD-1 CD8 T cells.
Etienne Humblin, Isabel Korpas, Nataliya Prokhnevska, Abishek Vaidya, Jiahua Lu, Brian D Brown

bioRxiv· September 2024

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Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8 thymocytes.
Yuanyuan You, Josefine Dunst, Kewei Ye, Patrick A Sandoz, Annika Reinhardt, Brian D Brown

Nat Immunol· August 2024

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The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program.
Oliver T Burton, Orian Bricard, Samar Tareen, Vaclav Gergelits, Simon Andrews, Brian D Brown

Immunity· July 2024

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Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors.
Samarth Hegde, Bruno Giotti, Brian Y Soong, Laszlo Halasz, Jessica Le Berichel, Brian D Brown

bioRxiv· June 2024

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Accelerating diabetic wound healing by ROS-scavenging lipid nanoparticle-mRNA formulation.
Siyu Wang, Yuebao Zhang, Yichen Zhong, Yonger Xue, Zhengwei Liu, Brian D Brown

Proc Natl Acad Sci U S A· May 2024

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An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis.
Nelson M LaMarche, Samarth Hegde, Matthew D Park, Barbara B Maier, Leanna Troncoso, Brian D Brown

Nature· January 2024

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RNA vaccines: A transformational advance.
Brian D Brown, Anthony S Fauci, Yasmine Belkaid, Miriam Merad

Immunity· December 2023

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Pattern recognition receptor agonists in pathogen vaccines mediate antitumor T-cell cross-priming.
Mark Aleynick, Judit Svensson-Arvelund, Gvantsa Pantsulaia, Kristy Kim, Samuel A Rose, Brian D Brown

J Immunother Cancer· July 2023

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