Publications by authors named "Brian D Freibaum"

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ASPL couples the assembly of stress granules with their VCP-mediated disassembly.
Gautam Pareek, Dongfang Li, Bo Wang, Jinjun Wu, Brian D Freibaum

Sci Adv· October 2025

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Activation of the mitochondrial unfolded protein response regulates the dynamic formation of stress granules.
Marta Lopez-Nieto, Zhaozhi Sun, Emily Relton, Rahme Safakli, Brian D Freibaum

J Cell Sci· May 2025

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Author Correction: Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.
Nisha M Badders, Ane Korff, Helen C Miranda, Pradeep K Vuppala, Rebecca B Smith, Brian D Freibaum

Nat Med· March 2024

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Identification of small molecule inhibitors of G3BP-driven stress granule formation.
Brian D Freibaum, James Messing, Haruko Nakamura, Ugur Yurtsever, Jinjun Wu

J Cell Biol· March 2024

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Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity.
Craig L Bennett, Somasish Dastidar, Frederick J Arnold, Spencer U McKinstry, Cameron Stockford, Brian D Freibaum

Acta Neuropathol Commun· October 2023

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A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.
Abner Gonzalez, Hong Joo Kim, Brian D Freibaum, Ho Yee Joyce Fung, Chad A Brautigam

Structure· August 2023

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Dynamic mapping of proteome trafficking within and between living cells by TransitID.
Wei Qin, Joleen S Cheah, Charles Xu, James Messing, Brian D Freibaum

Cell· July 2023

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Identification of small molecule inhibitors of G3BP-driven stress granule formation.
Brian D Freibaum, James Messing, Haruko Nakamura, Ugur Yurtsever, Jinjun Wu

bioRxiv· June 2023

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Dynamic mapping of proteome trafficking within and between living cells by TransitID.
Wei Qin Xu, Joleen S Cheah, Charles Xu, James Messing, Brian D Freibaum

bioRxiv· February 2023

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A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 is linked to neurodevelopmental disorders.
Abner Gonzalez, Hong Joo Kim, Brian D Freibaum, Ho Yee Joyce Fung, Chad A Brautigam

bioRxiv· January 2023

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High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate.
Brian D Freibaum, James Messing, Peiguo Yang, Hong Joo Kim, J Paul Taylor

J Cell Biol· March 2021

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Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Christian Haenig, Nir Atias, Alexander K Taylor, Arnon Mazza, Martin H Schaefer, Brian D Freibaum

Cell Rep· August 2020

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Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.
Kristian W Pajtler, Ji Wen, Martin Sill, Tong Lin, Wilda Orisme, Brian D Freibaum

Acta Neuropathol· August 2018

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Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.
Nisha M Badders, Ane Korff, Helen C Miranda, Pradeep K Vuppala, Rebecca B Smith, Brian D Freibaum

Nat Med· May 2018

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The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD.
Brian D Freibaum, J Paul Taylor

Front Mol Neurosci· February 2017

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C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.
Kyung-Ha Lee, Peipei Zhang, Hong Joo Kim, Diana M Mitrea, Mohona Sarkar, Brian D Freibaum

Cell· October 2016

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Genetic interaction of hnRNPA2B1 and DNAJB6 in a Drosophila model of multisystem proteinopathy.
Songqing Li, Peipei Zhang, Brian D Freibaum, Nam Chul Kim, Regina-Maria Kolaitis

Hum Mol Genet· March 2016

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GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.
Brian D Freibaum, Yubing Lu, Rodrigo Lopez-Gonzalez, Nam Chul Kim, Sandra Almeida

Nature· September 2015

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TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1.
Fang He, Amy Krans, Brian D Freibaum, J Paul Taylor, Peter K Todd

Hum Mol Genet· October 2014

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Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.
Nael H Alami, Rebecca B Smith, Monica A Carrasco, Luis A Williams, Christina S Winborn, Brian D Freibaum

Neuron· February 2014

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TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.
Gillian P Ritson, Sara K Custer, Brian D Freibaum, Jake B Guinto, Dyanna Geffel

J Neurosci· June 2010

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Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.
Brian D Freibaum, Raghu K Chitta, Anthony A High, J Paul Taylor

J Proteome Res· February 2010

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Distinct functions of POT1 at telomeres.
Katharine S Barrientos, Megan F Kendellen, Brian D Freibaum, Blaine N Armbruster, Katherine T Etheridge

Mol Cell Biol· September 2008

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The protein hSnm1B is stabilized when bound to the telomere-binding protein TRF2.
Brian D Freibaum, Christopher M Counter

J Biol Chem· August 2008

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hSnm1B is a novel telomere-associated protein.
Brian D Freibaum, Christopher M Counter

J Biol Chem· June 2006

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