Publications by authors named "Brian D Hobbs"

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Assessing inflammatory protein biomarkers in COPD subjects with and without alpha-1 antitrypsin deficiency.
Matthew Moll, Brian D Hobbs, Katherine A Pratte, Chengyue Zhang, Auyon J Ghosh

Respir Res· July 2025

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Omic Risk Scores are Associated with COPD-related Traits Across Three Cohorts.
Iain R Konigsberg, Luciana B Vargas, Katherine A Pratte, Daniel E Guzman, Tess D Pottinger, Brian D Hobbs

medRxiv· June 2025

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Deep Learning of Suboptimal Spirometry to Predict Respiratory Outcomes and Mortality.
Davin Hill, Max Torop, Aria Masoomi, Peter J Castaldi, Edwin K Silverman, Brian D Hobbs

Res Sq· June 2025

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Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.
Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, Heather M Highland, Nathalie Chami, Brian D Hobbs

Nat Commun· April 2025

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Polygenic Risk Score Added to Conventional Case Finding to Identify Undiagnosed Chronic Obstructive Pulmonary Disease.
Jingzhou Zhang, Brian D Hobbs, Edwin K Silverman, David Sparrow, Victor E Ortega

JAMA· March 2025

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Identifying chronic obstructive pulmonary disease subtypes using multi-trait genetics.
Andrey Ziyatdinov, Brian D Hobbs, Samir Kanaan-Izquierdo, Matthew Moll, Phuwanat Sakornsakolpat

EBioMedicine· March 2025

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Lung Transcriptomics Link Emphysema to Barrier Dysfunction and Macrophage Subpopulations.
Robin Lu, Andrew Gregory, Rahul Suryadevara, Zhonghui Xu, Dhawal Jain, Brian D Hobbs

Am J Respir Crit Care Med· January 2025

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Sex-Biased Regulation of Extracellular Matrix Genes in Chronic Obstructive Pulmonary Disease.
Camila M Lopes-Ramos, Katherine H Shutta, Min Hyung Ryu, Yichen Huang, Enakshi Saha, Brian D Hobbs

Am J Respir Cell Mol Biol· January 2025

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Peripheral blood miRNAs are associated with airflow below threshold in children with asthma.
Anshul Tiwari, Brian D Hobbs, Rinku Sharma, Jiang Li, Alvin T Kho

Respir Res· January 2025

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Assessing Inflammatory Protein Biomarkers in COPD Subjects with and without Alpha-1 Antitrypsin Deficiency.
Matthew Moll, Brian D Hobbs, Katherine A Pratte, Chengyue Zhang, Auyon J Ghosh

medRxiv· January 2025

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Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes in the COPDGene and ECLIPSE cohort studies.
Matthew Moll, Julian Hecker, John Platig, Jingzhou Zhang, Auyon J Ghosh, Brian D Hobbs

EBioMedicine· December 2024

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Genetically Predicted Body Mass Index and Mortality in Chronic Obstructive Pulmonary Disease.
Jingzhou Zhang, Matthew Moll, Brian D Hobbs, Per Bakke, Elizabeth A Regan

Am J Respir Crit Care Med· October 2024

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Partial correlation network analysis identifies coordinated gene expression within a regional cluster of COPD genome-wide association signals.
Michele Gentili, Kimberly Glass, Enrico Maiorino, Brian D Hobbs, Zhonghui Xu

PLoS Comput Biol· October 2024

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A protein risk score for all-cause and respiratory-specific mortality in non-Hispanic white and African American individuals who smoke.
Matthew Moll, Katherine A Pratte, Catherine L Debban, Congjian Liu, Steven A Belinsky, Brian D Hobbs

Sci Rep· September 2024

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Unsupervised representation learning on high-dimensional clinical data improves genomic discovery and prediction.
Taedong Yun, Justin Cosentino, Babak Behsaz, Zachary R McCaw, Davin Hill, Brian D Hobbs

Nat Genet· August 2024

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Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs

Nat Genet· May 2024

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Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes.
Matthew Moll, Julian Hecker, John Platig, Jingzhou Zhang, Auyon J Ghosh, Brian D Hobbs

medRxiv· May 2024

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Clinical factors associated with racial differences in the prevalence of occult hypoxemia: a retrospective case-control study.
Sofia K Mettler, Nipith Charoenngam, Aunchalee Jaroenlapnopparat, Courtney Tern, Nutchapon Xanthavanij, Brian D Hobbs

medRxiv· March 2024

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Polygenic risk scores identify heterogeneity in asthma and chronic obstructive pulmonary disease.
Matthew Moll, Joanne E Sordillo, Auyon J Ghosh, Lystra P Hayden, Gregory McDermott, Brian D Hobbs

J Allergy Clin Immunol· December 2023

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Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function.
Jeong H Yun, M A Wasay Khan, Auyon Ghosh, Brian D Hobbs, Peter J Castaldi

Am J Respir Crit Care Med· December 2023

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Augmentation Therapy for Severe Alpha-1 Antitrypsin Deficiency Improves Survival and Is Decoupled from Spirometric Decline-A Multinational Registry Analysis.
Daniel D Fraughen, Auyon J Ghosh, Brian D Hobbs, Georg-Christian Funk, Tobias Meischl

Am J Respir Crit Care Med· November 2023

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Plasma metabolomics and quantitative interstitial abnormalities in ever-smokers.
Bina Choi, Raúl San José Estépar, Suneeta Godbole, Jeffrey L Curtis, Jennifer M Wang, Brian D Hobbs

Respir Res· November 2023

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A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities.
Matthew Moll, Anna L Peljto, John S Kim, Hanfei Xu, Catherine L Debban, Brian D Hobbs

Am J Respir Crit Care Med· October 2023

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Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.
Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Brian D Hobbs

Nat Genet· October 2023

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WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.
Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, Heather M Highland, Nathalie Chami, Brian D Hobbs

medRxiv· August 2023

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