Publications by authors named "Brian Flesner"

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Preliminary evaluation of the safety and feasibility of toll-like receptor ligand CB101 combined with hypofractionated radiation therapy in canine head and neck cancer: a pilot study.
Audrey Ghanian, June DiBona, Lili Duda, Xiaowei Xu, John Nicholas Lukens, Brian Flesner

Vet Oncol· August 2025

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A combination of pre- and intraoperative techniques identifies sentinel lymph nodes in dogs with thyroid carcinoma: A pilot study.
Maureen A Griffin, Deanna R Worley, Brian K Flesner, Jennifer Reetz, David E Holt

Vet Surg· May 2025

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Immunological responses and clinical outcomes in dogs with osteosarcoma receiving standard therapy and a Listeria vaccine expressing HER2.
Nicola J Mason, Laura Selmic, Audrey Ruple, Cheryl A London, Lisa Barber, Brian Flesner

Mol Ther· April 2025

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Proof-of-concept evaluation of next-generation sequencing-based liquid biopsy for non-invasive cancer detection in cats.
Carlos A Ruiz-Perez, Prachi Nakashe, Maggie A Marshall, Francesco Marass, Tuong Tang, Brian K Flesner

Front Vet Sci· September 2024

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Clinical validation of a blood-based liquid biopsy test integrating cell-free DNA quantification and next-generation sequencing for cancer screening in dogs.
Andi Flory, Carlos A Ruiz-Perez, Ana G Clavere-Graciette, Jill M Rafalko, Allison L O'Kell, Brian K Flesner

J Am Vet Med Assoc· May 2024

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Effects of neoadjuvant zoledronate and radiation therapy on cell survival, cell cycle distribution, and clinical status in canine osteosarcoma.
Carissa J Norquest, Anita Rogic, Phyllis A Gimotty, Charles A Maitz, Hansjorg Rindt, Brian K Flesner

Front Vet Sci· January 2024

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Next-generation sequencing-based liquid biopsy may be used for detection of residual disease and cancer recurrence monitoring in dogs.
Angela L McCleary-Wheeler, Patrick C Fiaux, Brian K Flesner, Carlos A Ruiz-Perez, Lisa M McLennan

Am J Vet Res· December 2023

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Safety of TCMCB07, a melanocortin-4 antagonist peptide, in dogs with naturally occurring cachexia.
Sandra M Axiak-Bechtel, Stacey B Leach, Jessica R Newton-Northup, Rowan J Milner, Stacey A Fox-Alvarez, Brian K Flesner

J Vet Intern Med· November 2023

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Metagenomic Analysis of DNA Viruses with Targeted Sequence Capture of Canine Lobular Orbital Adenomas and Normal Conjunctiva.
Elizabeth A F Schaefer, Shirley Chu, Kristine M Wylie, Todd N Wylie, Obi L Griffith, Brian K Flesner

Microorganisms· April 2023

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Resolution of paraneoplastic hypoglycemia following nephroureterectomy for treatment of canine renal cell carcinoma: Case report.
Yael Huerta, Jennifer Lenz, Brian Flesner, Brittany Abrams, Hayley Amerman

Front Vet Sci· March 2023

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Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs.
Amy K LeBlanc, Christina N Mazcko, Timothy M Fan, David M Vail, Brian K Flesner

Mol Cancer Ther· October 2022

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Biodistribution and image characteristics of I-positron emission tomography in dogs with neuroendocrine neoplasia.
Kate L Shumway, Jeffrey N Bryan, Lindsay L Donnelly, Brian K Flesner, Jimmy C Lattimer

Vet Radiol Ultrasound· May 2022

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Fracture rate and time to fracture in dogs with appendicular osteosarcoma receiving finely fractionated compared to coarsely fractionated radiation therapy: A single institution study.
Carissa J Norquest, Charles A Maitz, Deborah A Keys, Melanie Moore, Jeffrey N Bryan, Brian K Flesner

Vet Med Sci· May 2022

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Clinical validation of a next-generation sequencing-based multi-cancer early detection "liquid biopsy" blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study.
Andi Flory, Kristina M Kruglyak, John A Tynan, Lisa M McLennan, Jill M Rafalko, Brian K Flesner

PLoS One· April 2022

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Paired 18F-Fluorodeoxyglucose (18F-FDG), and 64Cu-Copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone) (64Cu-ATSM) PET Scans in Dogs with Spontaneous Tumors and Evaluation for Hypoxia-Directed Therapy.
Charles A Maitz, Deborah Tate, Sandra Bechtel, Joni Lunceford, Carolyn Henry, Brian Flesner

Radiat Res· March 2022

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Toxicity, outcome, and management of anthracycline overdoses in 16 dogs.
Haylie C Lawson, Margaret L Musser, Rebecca Regan, Antony S Moore, Ann Hohenhaus, Brian Flesner

J Vet Intern Med· January 2022

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A Pilot Study of Cancer-Induced Bone Pain Using Validated Owner Questionnaires, Serum N-Telopeptide Concentration, Kinetic Analysis, and PET/CT.
Brian K Flesner, Bryan T Torres, Kyle D Hutcheson, Hansjörg Rindt, Amy R Zalcman

Front Vet Sci· December 2021

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Considerations related to the use of molecular diagnostic tests in veterinary clinical and regulatory practice.
John R Middleton, Rodman G Getchell, Brian K Flesner, Warren J Hess, Philip J Johnson

J Am Vet Med Assoc· September 2021

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A Retrospective Evaluation of Chemotherapy Overdoses in Dogs and Cats.
Margaret L Musser, Kaitlin M Curran, Brian K Flesner, Chad M Johannes

Front Vet Sci· September 2021

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Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 Dogs.
Amy K LeBlanc, Christina N Mazcko, Aswini Cherukuri, Erika P Berger, William C Kisseberth, Brian K Flesner

Clin Cancer Res· June 2021

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A 3D-printed Apparatus for Imaging Multiple Rats Simultaneously.
Nicholas J Harrison, Kate L Shumway, Sarah A Hansen, Charles A Maitz, Lori A Thombs, Brian K Flesner

Comp Med· April 2021

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Biochemical, functional, and histopathologic characterization of lomustine-induced liver injury in dogs.
Andrea M Dedeaux, Brian K Flesner, Jennifer M Reinhart, Ingeborg M Langohr, Roman Husnik

Am J Vet Res· October 2020

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Autologous cancer cell vaccination, adoptive T-cell transfer, and interleukin-2 administration results in long-term survival for companion dogs with osteosarcoma.
Brian K Flesner, Gary W Wood, Pamela Gayheart-Walsten, F Lynn Sonderegger, Carolyn J Henry

J Vet Intern Med· September 2020

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Long-Term Survival and Glycemic Control with Toceranib Phosphate and Prednisone for a Metastatic Canine Insulinoma.
Brian K Flesner, Jon M Fletcher, Taylor Smithee, Bonnie Boudreaux

J Am Anim Hosp Assoc· August 2019

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Papillomavirus DNA not detected in canine lobular orbital adenoma and normal conjunctival tissue.
Elizabeth A F Schaefer, Shirley Chu, Jacqueline W Pearce, Jeffrey N Bryan, Brian K Flesner

BMC Vet Res· July 2019

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