Publications by authors named "Brian Freed"

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Elovl1 inhibition reduced very long chain fatty acids in a mouse model of adrenoleukodystrophy.
Jeremy Y Huang, Brian Freed, Martin Hanus, Kelly Keefe, Ming Sum Ruby Chiang

iScience· September 2025

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Substitution of Glutamic Acid at Position 71 of DRβ1*04:01 and Collagen-Specific Tolerance Without Alloreactivity.
Vibha Jha, Brian M Freed, Elizabeth R Sunderhaus, Jessica E Lee, Edward B Prage

Arthritis Rheumatol· May 2025

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HLA evolutionary divergence (HED) informs the effect of HLA-B mismatch on outcomes after haploidentical transplantation.
Melhem Solh, Michael T Aubrey, Xu Zhang, Asad Bashey, Brian M Freed

Bone Marrow Transplant· October 2024

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Results of the Phase 1 Open-Label Safety Study of Umbilical Cord Lining Mesenchymal Stromal/Stem Cells (Corlicyte) to Heal Chronic Diabetic Foot Ulcers.
Cecilia C Low Wang, Tae Chong, Garrett Moore, Benjamin Echalier, Nicola Haakonsen, Brian M Freed

Biomedicines· June 2024

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A Randomized, Placebo-Controlled, Phase II Trial of Intravenous Allogeneic Non-HLA Matched, Unrelated Donor, Cord Blood Infusion for Ischemic Stroke.
Daniel T Laskowitz, Jesse Troy, Emily Poehlein, Ellen R Bennett, Elizabeth J Shpall, Brian Freed

Stem Cells Transl Med· February 2024

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and evidence that cigarette smoke-exposed T regulatory cells impair host immunity against .
Xiyuan Bai, Deepshikha Verma, Cindy Garcia, Ariel Musheyev, Kevin Kim, Brian M Freed

Front Cell Infect Microbiol· November 2023

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Cabozantinib sensitizes microsatellite stable colorectal cancer to immune checkpoint blockade by immune modulation in human immune system mouse models.
Julie Lang, Alexis D Leal, Juan A Marín-Jiménez, Sarah J Hartman, Jeremy Shulman, Brian M Freed

Front Oncol· November 2022

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HLA homozygosity is associated with Non-Hodgkin lymphoma.
Christina L Roark, Bethany E Ho, Michael T Aubrey, Cheri Anobile, Sapir Israeli, Brian M Freed

Hum Immunol· October 2022

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Lineage-Specific Relapse Prediction After Haploidentical Transplantation With Post-Transplant Cyclophosphamide Based on Recipient HLA-B-Leader Genotype and HLA-C-Group KIR Ligand.
Scott R Solomon, Michael T Aubrey, Xu Zhang, Katelin C Jackson, Christina L Roark, Brian M Freed

Transplant Cell Ther· September 2022

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Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19.
Xiyuan Bai, Ashley M Buckle, Eszter K Vladar, Edward N Janoff, Reeti Khare, Brian M Freed

Sci Rep· April 2022

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Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19.
Xiyuan Bai, Ashley M Buckle, Eszter K Vladar, Edward N Janoff, Reeti Khare, Brian M Freed

Sci Rep· March 2022

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Testing Cancer Immunotherapy in a Human Immune System Mouse Model: Correlating Treatment Responses to Human Chimerism, Therapeutic Variables and Immune Cell Phenotypes.
Juan A Marín-Jiménez, Anna Capasso, Matthew S Lewis, Stacey M Bagby, Sarah J Hartman, Brian M Freed

Front Immunol· July 2021

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Blinding, sham, and treatment effects in randomized controlled trials for back pain in 2000-2019: A review and meta-analytic approach.
Brian Freed, Brian Williams, Xiaolu Situ, Victoria Landsman, Jeehyoung Kim

Clin Trials· June 2021

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Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice.
Thiago Alves da Costa, Jacob N Peterson, Julie Lang, Jeremy Shulman, Xiayuan Liang, Brian M Freed

Proc Natl Acad Sci U S A· April 2021

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Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19.
Xiyuan Bai, Joseph Hippensteel, Alida Leavitt, James P Maloney, David Beckham, Brian M Freed

Med Hypotheses· January 2021

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HLA-DR53 (DRB4∗01) associates with nickel sensitization.
Yan Zhang, Kirsten M Anderson, Brian M Freed, Shaodong Dai, Karin A Pacheco

Ann Allergy Asthma Immunol· November 2020

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Complement fragments are biomarkers of antibody-mediated endothelial injury.
Erik Stites, Brandon Renner, Jennifer Laskowski, Moglie Le Quintrec, Zhiying You, Brian Freed

Mol Immunol· February 2020

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Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment.
Julie Lang, Anna Capasso, Kimberly R Jordan, Jena D French, Adwitiya Kar, Brian M Freed

J Clin Endocrinol Metab· January 2020

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Pulmonary alveolar proteinosis: An autoimmune disease lacking an HLA association.
Kirsten Anderson, Brenna Carey, Allison Martin, Christina Roark, Claudia Chalk, Brian Freed

PLoS One· December 2019

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Epstein-Barr Virus Type 2 Infects T Cells and Induces B Cell Lymphomagenesis in Humanized Mice.
Carrie B Coleman, Julie Lang, Lydia A Sweet, Nicholas A Smith, Brian M Freed

J Virol· November 2018

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Lower tacrolimus exposure and time in therapeutic range increase the risk of de novo donor-specific antibodies in the first year of kidney transplantation.
Scott Davis, Jane Gralla, Patrick Klem, Suhong Tong, Gina Wedermyer, Brian Freed

Am J Transplant· April 2018

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Selecting the Best Donor for Haploidentical Transplant: Impact of HLA, Killer Cell Immunoglobulin-Like Receptor Genotyping, and Other Clinical Variables.
Scott R Solomon, Michael T Aubrey, Xu Zhang, Allison Piluso, Brian M Freed

Biol Blood Marrow Transplant· April 2018

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Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice.
Julie Lang, Bicheng Zhang, Margot Kelly, Jacob N Peterson, Jacob Barbee, Brian M Freed

Blood Adv· December 2017

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Programmed Death 1 Expression on CD4 T Cells Predicts Mortality after Allogeneic Stem Cell Transplantation.
Henning Schade, Sharon Sen, C Preston Neff, Brian M Freed, Dexiang Gao

Biol Blood Marrow Transplant· December 2016

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How transplant centers deal with the dextran shortage: recommendations for comparing alternatives.
Colleen Brady, Sue Armitage, Brian Freed, Merry Duffy, Anne Gass

Transfusion· November 2016

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