Publications by authors named "Brian Hendrich"

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Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency.
David Lando, Xiaoyan Ma, Yang Cao, Aleksandra Jartseva, Tim J Stevens, Brian D Hendrich

Mol Cell· April 2024

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The Nucleosome Remodelling and Deacetylation complex coordinates the transcriptional response to lineage commitment in pluripotent cells.
Bertille Montibus, Ramy Ragheb, Evangelia Diamanti, Sara-Jane Dunn, Nicola Reynolds, Brian Hendrich

Biol Open· January 2024

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Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by the nucleosome remodelling and deacetylation complex.
Ramy Ragheb, Sarah Gharbi, Julie Cramard, Oluwaseun Ogundele, Susan L Kloet, Brian Hendrich

Stem Cell Res· July 2020

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Chromatin Remodelling Proteins and Cell Fate Decisions in Mammalian Preimplantation Development.
Anzy Miller, Brian Hendrich

Adv Anat Embryol Cell Biol· February 2020

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The Nucleosome Remodelling and Deacetylation complex suppresses transcriptional noise during lineage commitment.
Thomas Burgold, Michael Barber, Susan Kloet, Julie Cramard, Sarah Gharbi, Brian Hendrich

EMBO J· June 2019

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PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex.
Stephanie Link, Ramona M M Spitzer, Maryam Sana, Mario Torrado, Moritz C Völker-Albert, Brian Hendrich

Nat Commun· October 2018

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The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression.
Susanne Bornelöv, Nicola Reynolds, Maria Xenophontos, Sarah Gharbi, Ewan Johnstone, Brian Hendrich

Mol Cell· July 2018

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FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.
Srinjan Basu, Lisa-Maria Needham, David Lando, Edward J R Taylor, Kai J Wohlfahrt, Brian Hendrich

Nat Commun· June 2018

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Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell.
David Lando, Srinjan Basu, Tim J Stevens, Andy Riddell, Kai J Wohlfahrt, Brian Hendrich

Nat Protoc· May 2018

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Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program.
Stephen J Loughran, Federico Comoglio, Fiona K Hamey, Alice Giustacchini, Youssef Errami, Brian Hendrich

J Exp Med· October 2017

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3D structures of individual mammalian genomes studied by single-cell Hi-C.
Tim J Stevens, David Lando, Srinjan Basu, Liam P Atkinson, Yang Cao, Brian Hendrich

Nature· April 2017

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A high-resolution map of transcriptional repression.
Ziwei Liang, Karen E Brown, Thomas Carroll, Benjamin Taylor, Isabel Ferreirós Vidal, Brian Hendrich

Elife· March 2017

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Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex.
Anzy Miller, Meryem Ralser, Susan L Kloet, Remco Loos, Ryuichi Nishinakamura, Brian Hendrich

Development· September 2016

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Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.
Aoife O'Shaughnessy-Kirwan, Jason Signolet, Ita Costello, Sarah Gharbi, Brian Hendrich

Development· August 2015

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The function of chromatin modifiers in lineage commitment and cell fate specification.
Jason Signolet, Brian Hendrich

FEBS J· May 2015

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The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex.
Erin Knock, João Pereira, Patrick D Lombard, Andrew Dimond, Donna Leaford, Brian Hendrich

Neural Dev· May 2015

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MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner.
Rodrigo L Dos Santos, Luca Tosti, Aliaksandra Radzisheuskaya, Isabel M Caballero, Keisuke Kaji, Brian Hendrich

Cell Stem Cell· September 2014

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MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner.
Rodrigo L dos Santos, Luca Tosti, Aliaksandra Radzisheuskaya, Isabel M Caballero, Keisuke Kaji, Brian Hendrich

Cell Stem Cell· July 2014

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CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now.
Aoife O'Shaughnessy, Brian Hendrich

Biochem Soc Trans· June 2013

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MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line.
Bianca Bertulat, Maria Luigia De Bonis, Floriana Della Ragione, Anne Lehmkuhl, Manuela Milden, Brian Hendrich

PLoS One· April 2013

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Transcriptional repressors: multifaceted regulators of gene expression.
Nicola Reynolds, Aoife O'Shaughnessy, Brian Hendrich

Development· February 2013

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NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.
Nicola Reynolds, Paulina Latos, Antony Hynes-Allen, Remco Loos, Donna Leaford, Brian Hendrich

Cell Stem Cell· May 2012

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NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate.
Paulina A Latos, Christine Helliwell, Olukunbi Mosaku, Dominika A Dudzinska, Bryony Stubbs, Brian Hendrich

Biol Open· April 2012

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Sin3a is essential for the genome integrity and viability of pluripotent cells.
Patrick McDonel, Jeroen Demmers, David W M Tan, Fiona Watt, Brian D Hendrich

Dev Biol· March 2012

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NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression.
Nicola Reynolds, Mali Salmon-Divon, Heidi Dvinge, Antony Hynes-Allen, Gayan Balasooriya, Brian Hendrich

EMBO J· February 2012

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