Publications by authors named "Brian Howell"

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Inhibition of GCKIII kinases STK25 and MST3 mitigates organ lipotoxicity and enhances metabolic resilience under nutritional stress.
Emma Andersson, Xiangdong Gongye, Emmelie Cansby, Jingjing Zhang, Mara Caputo, Brian W Howell

BMC Med· September 2025

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Measurement of diets that are healthy, environmentally sustainable, affordable, and equitable: A scoping review of metrics, findings, and research gaps.
Patrick Webb, Kara Livingston Staffier, Hyomin Lee, Brian Howell, Kyra Battaglia

Front Nutr· April 2023

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Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer's disease pathogenesis.
Matthew Bracher-Smith, Ganna Leonenko, Emily Baker, Karen Crawford, Andrew C Graham, Brian W Howell

Neurobiol Aging· November 2022

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Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic Pathways.
Yeshwant Kurhe, Mara Caputo, Emmelie Cansby, Ying Xia, Sima Kumari, Brian W Howell

Cell Mol Gastroenterol Hepatol· April 2022

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GCKIII (Germinal Center Kinase III) Kinases STK24 and STK25 (Serine/Threonine Kinase 24 and 25) Inhibit Cavernoma Development.
Miriam Sartages, Mar García-Colomer, Cristina Iglesias, Brian W Howell, Manuel Macía

Stroke· March 2022

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Maternal Ethanol Exposure Acutely Elevates Src Family Kinase Activity in the Fetal Cortex.
Dandan Wang, Brian W Howell, Eric C Olson

Mol Neurobiol· October 2021

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STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development.
Tohru Matsuki, Akio Iio, Masashi Ueda, Yumi Tsuneura, Brian W Howell

J Neurosci· October 2021

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Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease.
Emmelie Cansby, Mara Caputo, Lei Gao, Nagaraj M Kulkarni, Annika Nerstedt, Brian W Howell

JCI Insight· December 2020

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Establishing best practices for structured NSQIP review.
Aaron J Cunningham, Brian Howell, Stephanie Polites, Sanjay Krishnaswami, Eryn Hughey

Am J Surg· May 2020

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Ethanol Exposure Transiently Elevates but Persistently Inhibits Tyrosine Kinase Activity and Impairs the Growth of the Nascent Apical Dendrite.
Dandan Wang, Joshua Enck, Brian W Howell, Eric C Olson

Mol Neurobiol· August 2019

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Identification of the kinase STK25 as an upstream activator of LATS signaling.
Sanghee Lim, Nicole Hermance, Tenny Mudianto, Hatim M Mustaly, Ian Paolo Morelos Mauricio, Brian W Howell

Nat Commun· April 2019

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Synaptic structural protein dysfunction leads to altered excitation inhibition ratios in models of autism spectrum disorder.
Brian W Howell, Kathleen M Smith

Pharmacol Res· January 2019

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STK25 regulates oxidative capacity and metabolic efficiency in adipose tissue.
Silva Sütt, Emmelie Cansby, Alexandra Paul, Manoj Amrutkar, Esther Nuñez-Durán, Brian W Howell

J Endocrinol· September 2018

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STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia.
Emmelie Cansby, Elin Magnusson, Esther Nuñez-Durán, Manoj Amrutkar, Matteo Pedrelli, Brian W Howell

Arterioscler Thromb Vasc Biol· August 2018

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Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway.
Leigh Dairaghi, Ellen Flannery, Paolo Giacobini, Aybike Saglam, Hassan Saadi, Brian W Howell

Front Cell Neurosci· August 2018

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The de novo autism spectrum disorder RELN R2290C mutation reduces Reelin secretion and increases protein disulfide isomerase expression.
Dawn B Lammert, Frank A Middleton, Jen Pan, Eric C Olson, Brian W Howell

J Neurochem· July 2017

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Conditional pulmonary over-expression of Claudin 6 during embryogenesis delays lung morphogenesis.
Felix R Jimenez, Samuel T Belgique, Joshua B Lewis, Scott A Albright, Cameron M Jones, Brian M Howell

Int J Dev Biol· November 2016

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RELN Mutations in Autism Spectrum Disorder.
Dawn B Lammert, Brian W Howell

Front Cell Neurosci· April 2016

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Differential Receptor for Advanced Glycation End Products Expression in Preeclamptic, Intrauterine Growth Restricted, and Gestational Diabetic Placentas.
Kristen L Alexander, Camilo A Mejia, Clinton Jordan, Michael B Nelson, Brian M Howell

Am J Reprod Immunol· February 2016

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Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model.
Manoj Amrutkar, Emmelie Cansby, Urszula Chursa, Esther Nuñez-Durán, Belén Chanclón, Brian W Howell

Diabetes· August 2015

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Transient downregulation of Dab1 protein levels during development leads to behavioral and structural deficits: relevance for psychiatric disorders.
Catia M Teixeira, Nuria Masachs, Ashraf Muhaisen, Carles Bosch, Javier Pérez-Martínez, Brian Howell

Neuropsychopharmacology· February 2014

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Novel Disabled-1-expressing neurons identified in adult brain and spinal cord.
Autumn D Abadesco, Marianne Cilluffo, Griselda M Yvone, Ellen M Carpenter, Brian W Howell

Eur J Neurosci· February 2014

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Acute inactivation of the serine-threonine kinase Stk25 disrupts neuronal migration.
Tohru Matsuki, Jianhua Chen, Brian W Howell

Neural Dev· November 2013

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Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice.
Bianka Brunne, Santos Franco, Elisabeth Bouché, Joachim Herz, Brian W Howell

Glia· August 2013

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Cell-autonomous inactivation of the reelin pathway impairs adult neurogenesis in the hippocampus.
Catia M Teixeira, Michelle M Kron, Nuria Masachs, Helen Zhang, Diane C Lagace, Brian W Howell

J Neurosci· August 2012

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