Publications by authors named "Brian Keppler"

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Middle-aged dogs with low and high Aβ CSF concentrations show differences in energy and stress related metabolic profiles in CSF.
Herman Borghys, Andrew Schwab, Brian Keppler

Heliyon· October 2024

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Inhaled glucocorticoid-induced metabolome changes in asthma.
Peter Daley-Yates, Brian Keppler, Noushin Brealey, Shaila Shabbir, Dave Singh

Eur J Endocrinol· September 2022

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Metabolomic changes related to airway inflammation, asthma pathogenesis and systemic activity following inhaled fluticasone furoate/vilanterol: a randomized controlled trial.
Peter Daley-Yates, Brian Keppler, Amanda Baines, George Bardsley, James Fingleton

Respir Res· September 2022

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Evidence for 2-Methoxyestradiol-Mediated Inhibition of Receptor Tyrosine Kinase RON in the Management of Prostate Cancer.
Izhar Singh Batth, Shih-Bo Huang, Michelle Villarreal, Jingjing Gong, Divya Chakravarthy, Brian Keppler

Int J Mol Sci· February 2021

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Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke.
Bjoern Titz, Justyna Szostak, Alain Sewer, Blaine Phillips, Catherine Nury, Brian Keppler

Comput Struct Biotechnol J· April 2020

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3-Aminobenzamide Blocks MAMP-Induced Callose Deposition Independently of Its Poly(ADPribosyl)ation Inhibiting Activity.
Brian D Keppler, Junqi Song, Jackson Nyman, Christian A Voigt, Andrew F Bent

Front Plant Sci· December 2018

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Palmatine suppresses glutamine-mediated interaction between pancreatic cancer and stellate cells through simultaneous inhibition of survivin and COL1A1.
Divya Chakravarthy, Amanda R Muñoz, Angel Su, Rosa F Hwang, Brian R Keppler

Cancer Lett· April 2018

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A transcriptomics approach uncovers novel roles for poly(ADP-ribosyl)ation in the basal defense response in Arabidopsis thaliana.
Amy G Briggs, Lori C Adams-Phillips, Brian D Keppler, Sophia G Zebell, Kyle C Arend

PLoS One· February 2018

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Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.
Filippo Zanetti, Bjoern Titz, Alain Sewer, Giuseppe Lo Sasso, Elena Scotti, Brian R Keppler

Food Chem Toxicol· March 2017

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Bioinformatic Identification and Analysis of Hydroxyproline-Rich Glycoproteins in Populus trichocarpa.
Allan M Showalter, Brian D Keppler, Xiao Liu, Jens Lichtenberg, Lonnie R Welch

BMC Plant Biol· October 2016

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PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses.
Junqi Song, Brian D Keppler, Robert R Wise, Andrew F Bent

PLoS Genet· May 2015

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A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process.
Shawn D Stuart, Alexandra Schauble, Sunita Gupta, Adam D Kennedy, Brian R Keppler

Cancer Metab· March 2014

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ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide.
Joana Soares, Brian R Keppler, Xihong Wang, Kuo-Hsiung Lee, Michael B Jarstfer

Bioorg Med Chem Lett· December 2011

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Emerging roles of the 26S proteasome in nuclear hormone receptor-regulated transcription.
Brian R Keppler, Trevor K Archer, H Karimi Kinyamu

Biochim Biophys Acta· February 2011

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Ubiquitin-dependent and ubiquitin-independent control of subunit stoichiometry in the SWI/SNF complex.
Brian R Keppler, Trevor K Archer

J Biol Chem· November 2010

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IRX14 and IRX14-LIKE, two glycosyl transferases involved in glucuronoxylan biosynthesis and drought tolerance in Arabidopsis.
Brian D Keppler, Allan M Showalter

Mol Plant· September 2010

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A bioinformatics approach to the identification, classification, and analysis of hydroxyproline-rich glycoproteins.
Allan M Showalter, Brian Keppler, Jens Lichtenberg, Dazhang Gu, Lonnie R Welch

Plant Physiol· June 2010

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BRACO19 analog dimers with improved inhibition of telomerase and hPot 1.
Yuan-Te Fu, Brian R Keppler, Joana Soares, Michael B Jarstfer

Bioorg Med Chem· March 2009

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Chromatin-modifying enzymes as therapeutic targets--Part 2.
Brian R Keppler, Trevor K Archer

Expert Opin Ther Targets· November 2008

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Chromatin-modifying enzymes as therapeutic targets--Part 1.
Brian R Keppler, Trevor K Archer

Expert Opin Ther Targets· October 2008

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Electron microscopic visualization of telomerase from Euplotes aediculatus bound to a model telomere DNA.
Nicole Fouché, Ian K Moon, Brian R Keppler, Jack D Griffith, Michael B Jarstfer

Biochemistry· August 2006

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The biochemical role of the heat shock protein 90 chaperone complex in establishing human telomerase activity.
Brian R Keppler, Allen T Grady, Michael B Jarstfer

J Biol Chem· July 2006

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A high-throughput assay for a human telomerase protein-human telomerase RNA interaction.
Brian R Keppler, Michael B Jarstfer

Anal Biochem· June 2006

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Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase.
Pamela K Dominick, Brian R Keppler, Jason D Legassie, Ian K Moon, Michael B Jarstfer

Bioorg Med Chem Lett· July 2004

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Inhibition of telomerase activity by preventing proper assemblage.
Brian R Keppler, Michael B Jarstfer

Biochemistry· January 2004

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