Publications by authors named "Brian M Samas"

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Organic NMR crystallography: enabling progress for applications to pharmaceuticals and plant cell walls.
Zainab Rehman, Jairah Lubay, W Trent Franks, Albert P Bartók, Emily K Corlett, Brian M Samas

Faraday Discuss· January 2025

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Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.
Katherine L Lee, Catherine M Ambler, David R Anderson, Brian P Boscoe, Andrea G Bree, Brian M Samas

J Med Chem· July 2017

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A highly enantioselective allylic amination reaction using a commercially available chiral rhodium catalyst: resolution of racemic allylic carbonates.
Derek C Vrieze, Garrett S Hoge, Perrine Z Hoerter, Jared T Van Haitsma, Brian M Samas

Org Lett· July 2009

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Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications.
Jie Jack Li, Donna M Iula, Maria N Nguyen, Lain-Yen Hu, Danielle Dettling, Brian M Samas

J Med Chem· November 2008

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