Publications by authors named "Brian Necela"

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BRAFV600E/pTERT double mutated papillary thyroid cancers exhibit immune gene suppression.
Ana-Maria Sigarteu Chindris, Michael Rivera, Yaohua Ma, Asha Nair, Yi Liu, Brian M Necela

Front Endocrinol (Lausanne)· December 2024

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Expression of c-erb-B2 oncoprotein as a neoantigen strategy to repurpose anti-neu antibody therapy in a model of melanoma.
Emmanuel M Gabriel, Brian Necela, Deborah Bahr, Sneha Vivekanandhan, Barath Shreeder

Sci Rep· October 2024

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Comprehensive profiling of cancer neoantigens from aberrant RNA splicing.
Daniel P Wickland, Colton McNinch, Erik Jessen, Brian Necela, Barath Shreeder

J Immunother Cancer· May 2024

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Higher and Sustained Cell-Mediated Immune Responses After 3 Doses of mRNA COVID-19 Vaccine in Patients With Inflammatory Bowel Disease on Anti-Tumor Necrosis Factor Therapy.
Freddy Caldera, Stacey Rolak, Francis A Farraye, Brian M Necela, Davitte Cogen

Clin Transl Gastroenterol· April 2024

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Expression of c-erb-B2 oncoprotein as a neoantigen strategy to repurpose anti-neu antibody therapy in a model of melanoma.
Emmanuel M Gabriel, Brian Necela, Deborah Bahr, Sneha Vivekanandhan, Barath Shreeder

Res Sq· April 2024

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Th17-inducing dendritic cell vaccines stimulate effective CD4 T cell-dependent antitumor immunity in ovarian cancer that overcomes resistance to immune checkpoint blockade.
Yan Luo, Barath Shreeder, James W Jenkins, Huashan Shi, Purushottam Lamichhane, Brian M Necela

J Immunother Cancer· November 2023

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Higher Cell-Mediated Immune Responses in Patients With Inflammatory Bowel Disease on Anti-TNF Therapy After COVID-19 Vaccination.
Freddy Caldera, Francis A Farraye, Brian M Necela, Davitte Cogen, Sumona Saha

Inflamm Bowel Dis· August 2023

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TRPC6 N338S is a gain-of-function mutant identified in patient with doxorubicin-induced cardiotoxicity.
Tong Lu, Xiaojing Sun, Brian M Necela, Hon-Chi Lee, Nadine Norton

Biochim Biophys Acta Mol Basis Dis· November 2022

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Trpc6 Promotes Doxorubicin-Induced Cardiomyopathy in Male Mice With Pleiotropic Differences Between Males and Females.
Nadine Norton, Katelyn A Bruno, Damian N Di Florio, Emily R Whelan, Anneliese R Hill, Brian M Necela

Front Cardiovasc Med· January 2022

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Association of Genetic Variants at With Chemotherapy-Related Heart Failure.
Nadine Norton, Julia E Crook, Liwei Wang, Janet E Olson, Jennifer M Kachergus, Brian M Necela

Front Cardiovasc Med· August 2020

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Folate receptor alpha expression associates with improved disease-free survival in triple negative breast cancer patients.
Nadine Norton, Bahaaeldin Youssef, David W Hillman, Aziza Nassar, Xochiquetzal J Geiger, Brian M Necela

NPJ Breast Cancer· February 2020

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Chromoanasynthesis is a common mechanism that leads to ERBB2 amplifications in a cohort of early stage HER2 breast cancer samples.
George Vasmatzis, Xue Wang, James B Smadbeck, Stephen J Murphy, Katherine B Geiersbach, Brian M Necela

BMC Cancer· July 2018

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Generation of HER2-specific antibody immunity during trastuzumab adjuvant therapy associates with reduced relapse in resected HER2 breast cancer.
Nadine Norton, Nicholas Fox, Christie-Ann McCarl, Kathleen S Tenner, Karla Ballman, Brian M Necela

Breast Cancer Res· June 2018

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The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC-derived cardiomyocytes.
Brian M Necela, Bianca C Axenfeld, Daniel J Serie, Jennifer M Kachergus, Edith A Perez

Clin Transl Med· December 2017

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Genome-wide association study of cardiotoxicity in the NCCTG N9831 (Alliance) adjuvant trastuzumab trial.
Daniel J Serie, Julia E Crook, Brian M Necela, Travis J Dockter, Xue Wang

Pharmacogenet Genomics· October 2017

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Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling.
Antonis Kourtidis, Brian Necela, Wan-Hsin Lin, Ruifeng Lu, Ryan W Feathers

J Cell Biol· October 2017

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Comprehensive Genomic Profiling of a Rare Thyroid Follicular Dendritic Cell Sarcoma.
Jaime I Davila, Jason S Starr, Steven Attia, Chen Wang, Ryan A Knudson, Brian M Necela

Rare Tumors· July 2017

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Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth.
Frederik Holst, Erling A Hoivik, William J Gibson, Amaro Taylor-Weiner, Steven E Schumacher, Brian M Necela

Sci Rep· June 2017

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Breast Cancer Clinical Trial of Chemotherapy and Trastuzumab: Potential Tool to Identify Cardiac Modifying Variants of Dilated Cardiomyopathy.
Daniel J Serie, Julia E Crook, Brian M Necela, Bianca C Axenfeld, Travis J Dockter

J Cardiovasc Dev Dis· May 2017

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Intrinsic Subtype and Therapeutic Response Among HER2-Positive Breaty st Tumors from the NCCTG (Alliance) N9831 Trial.
Edith A Perez, Karla V Ballman, Afshin Mashadi-Hossein, Kathleen S Tenner, Jennifer M Kachergus, Brian M Necela

J Natl Cancer Inst· February 2017

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Assessment of Tumor Heterogeneity, as Evidenced by Gene Expression Profiles, Pathway Activation, and Gene Copy Number, in Patients with Multifocal Invasive Lobular Breast Tumors.
Nadine Norton, Pooja P Advani, Daniel J Serie, Xochiquetzal J Geiger, Brian M Necela

PLoS One· August 2016

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Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth.
Frederik Holst, Erling A Hoivik, William J Gibson, Amaro Taylor-Weiner, Steven E Schumacher, Brian M Necela

Sci Rep· June 2016

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Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth.
Frederik Holst, Erling A Hoivik, William J Gibson, Amaro Taylor-Weiner, Steven E Schumacher, Brian M Necela

Sci Rep· May 2016

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Folate receptor-α (FOLR1) expression and function in triple negative tumors.
Brian M Necela, Jennifer A Crozier, Cathy A Andorfer, Laura Lewis-Tuffin, Jennifer M Kachergus

PLoS One· February 2016

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Correction: Folate receptor-α (FOLR1) expression and function in triple negative tumors.
Brian M Necela, Jennifer A Crozier, Cathy A Andorfer, Laura Lewis-Tuffin, Jennifer M Kachergus

PLoS One· September 2015

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