Publications by authors named "Brian Ness"

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Mass Cytometry reveals unique phenotypic patterns associated with subclonal diversity and outcomes in multiple myeloma.
Linda B Baughn, Erik Jessen, Neeraj Sharma, Hongwei Tang, James B Smadbeck, Brian Van Ness

Blood Cancer J· May 2023

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Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma.
Ian D Ferguson, Yu-Hsiu T Lin, Christine Lam, Hao Shao, Kevin M Tharp, Brian Van Ness

Cell Chem Biol· August 2022

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Single-Cell Proteomics and Tumor RNAseq Identify Novel Pathways Associated With Clofazimine Sensitivity in PI- and IMiD- Resistant Myeloma, and Putative Stem-Like Cells.
Harish Kumar, Suman Mazumder, Neeraj Sharma, Sayak Chakravarti, Mark D Long, Brian G Van Ness

Front Oncol· May 2022

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Understanding Drug Sensitivity and Tackling Resistance in Cancer.
Jeffrey W Tyner, Franziska Haderk, Anbarasu Kumaraswamy, Linda B Baughn, Brian Van Ness

Cancer Res· April 2022

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secDrug: a pipeline to discover novel drug combinations to kill drug-resistant multiple myeloma cells using a greedy set cover algorithm and single-cell multi-omics.
Harish Kumar, Suman Mazumder, Sayak Chakravarti, Neeraj Sharma, Ujjal Kumar Mukherjee, Brian G Van Ness

Blood Cancer J· March 2022

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Pharmacogenomics education, research and clinical implementation in the state of Minnesota.
Jeffrey R Bishop, R Stephanie Huang, Jacob T Brown, Pawel Mroz, Steven G Johnson, Brian Van Ness

Pharmacogenomics· July 2021

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In vitro and ex vivo gene expression profiling reveals differential kinetic response of HSPs and UPR genes is associated with PI resistance in multiple myeloma.
Amit Kumar Mitra, Harish Kumar, Vijay Ramakrishnan, Li Chen, Linda Baughn, Brian G Van Ness

Blood Cancer J· July 2020

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Discovering genetic interactions bridging pathways in genome-wide association studies.
Gang Fang, Wen Wang, Vanja Paunic, Hamed Heydari, Michael Costanzo, Brian Van Ness

Nat Commun· September 2019

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Identification of a de novo FOXP1 mutation and incidental discovery of inherited genetic variants contributing to a case of autism spectrum disorder and epilepsy.
Kristy Jay, Amit Mitra, Taylor Harding, David Matthes, Brian Van Ness

Mol Genet Genomic Med· July 2019

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The future of myeloma precision medicine: integrating the compendium of known drug resistance mechanisms with emerging tumor profiling technologies.
Taylor Harding, Linda Baughn, Shaji Kumar, Brian Van Ness

Leukemia· April 2019

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Molecular signatures of multiple myeloma progression through single cell RNA-Seq.
Jin Sung Jang, Ying Li, Amit Kumar Mitra, Lintao Bi, Alexej Abyzov, Brian Van Ness

Blood Cancer J· January 2019

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EZH2 inhibitors sensitize myeloma cell lines to panobinostat resulting in unique combinatorial transcriptomic changes.
Taylor Harding, Jessica Swanson, Brian Van Ness

Oncotarget· April 2018

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Pragmatic Tools for Sharing Genomic Research Results with the Relatives of Living and Deceased Research Participants.
Susan M Wolf, Emily Scholtes, Barbara A Koenig, Gloria M Petersen, Susan A Berry, Brian Van Ness

J Law Med Ethics· March 2018

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Development of expression-based biomarkers of Dasatinib response in hematologic malignancies.
Monica K Akre, Amit Mitra, Wen Wang, Chad L Myers, Brian Van Ness

Blood Cancer J· December 2017

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Phenotypic and functional characterization of a bortezomib-resistant multiple myeloma cell line by flow and mass cytometry.
Linda B Baughn, Zohar Sachs, Klara E Noble-Orcutt, Amit Mitra, Brian G Van Ness

Leuk Lymphoma· August 2017

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Glutaminase inhibitor CB-839 synergizes with carfilzomib in resistant multiple myeloma cells.
Ravyn M Thompson, Dominik Dytfeld, Leticia Reyes, Reeder M Robinson, Brittany Smith, Brian G Van Ness

Oncotarget· May 2017

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A de novo splice site mutation in EHMT1 resulting in Kleefstra syndrome with pharmacogenomics screening and behavior therapy for regressive behaviors.
Amit Kumar Mitra, Jessica Dodge, Jody Van Ness, Israel Sokeye, Brian Van Ness

Mol Genet Genomic Med· March 2017

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Risk of multiple myeloma in a case-spouse study.
Gabriella Andreotti, Michael Katz, Antje Hoering, Brian Van Ness, John Crowley

Leuk Lymphoma· January 2017

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Returning a Research Participant's Genomic Results to Relatives: Analysis and Recommendations.
Susan M Wolf, Rebecca Branum, Barbara A Koenig, Gloria M Petersen, Susan A Berry, Brian Van Ness

J Law Med Ethics· January 2017

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Returning a Research Participant's Genomic Results to Relatives: Perspectives from Managers of Two Distinct Research Biobanks.
Gloria M Petersen, Brian Van Ness

J Law Med Ethics· January 2017

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PIAS1 Promotes Lymphomagenesis through MYC Upregulation.
Andrea Rabellino, Margherita Melegari, Van S Tompkins, Weina Chen, Brian G Van Ness

Cell Rep· June 2016

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Fine-Mapping of 18q21.1 Locus Identifies Single Nucleotide Polymorphisms Associated with Nonsyndromic Cleft Lip with or without Cleft Palate.
Amit K Mitra, Holly A F Stessman, Robert J Schaefer, Wen Wang, Chad L Myers, Brian G Van Ness

Front Genet· May 2016

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Applications and limitations in translating genomics to clinical practice.
Brian Van Ness

Transl Res· February 2016

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Utilization of translational bioinformatics to identify novel biomarkers of bortezomib resistance in multiple myeloma.
Deanna J Fall, Holly Stessman, Sagar S Patel, Zohar Sachs, Brian G Van Ness

J Cancer· November 2014

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Bortezomib resistance can be reversed by induced expression of plasma cell maturation markers in a mouse in vitro model of multiple myeloma.
Holly A F Stessman, Aatif Mansoor, Fenghuang Zhan, Michael A Linden, Brian Van Ness

PLoS One· August 2014

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