Publications by authors named "Brian Overholser"

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Dihydrotestosterone Pretreatment Diminishes the Severity of Drug-Induced Torsades de Pointes.
James E Tisdale, Heather A Jaynes, Brian R Overholser, Kevin M Sowinski, Richard J Kovacs

J Cardiovasc Pharmacol· October 2025

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QTc Interval Changes in Preeclampsia vs. Normal Pregnancy: A Systematic Review and Meta-Analysis.
Omar A Aboshady, Jess Z Raffa, Sara K Quinney, James E Tisdale, Brian R Overholser

Clin Pharmacol Ther· June 2025

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Pharmacotherapy research landscape and knowledge gaps of opioids in maternal and pediatric populations.
Aditi Shendre, Xiaofu Liu, ChienWei Chiang, Andrew Goodwin, Samuel-Richard Oteng, Brian R Overholser

Pharmacotherapy· June 2025

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Drug-induced increase in dispersion of ventricular repolarization in patients with heart failure with preserved ejection fraction.
Fatimah Alhurayri, Heather A Jaynes, Brian R Overholser, Kevin M Sowinski, Richard J Kovacs

Int J Cardiol· January 2025

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Arrhythmias in Patients With Heart Failure Prescribed Dofetilide or Sotalol.
Chien-Yu Huang, Brian R Overholser, Kevin M Sowinski, Heather A Jaynes, Richard J Kovacs

JACC Adv· November 2024

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Drug-induced QT interval prolongation in patients with heart failure with preserved ejection fraction.
Chien-Yu Huang, Brian R Overholser, Kevin M Sowinski, Heather A Jaynes, Richard J Kovacs

PLoS One· August 2024

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Prolonged Exposure to Remdesivir Inhibits the Human Ether-A-Go-Go-Related Gene Potassium Current.
Enoch Amarh, James E Tisdale, Brian R Overholser

J Cardiovasc Pharmacol· September 2023

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Effects of oxycodone pharmacogenetics on postoperative analgesia and related clinical outcomes in children: a pilot prospective study.
Blessed W Aruldhas, Sara K Quinney, Senthil Packiasabapathy, Brian R Overholser, Olivia Raymond

Pharmacogenomics· March 2023

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Association of QT interval-prolonging drugs with clinical trial eligibility in patients with advanced cancer.
Elizabeth J Rowe, Tyler Shugg, Reynold C Ly, Santosh Philips, Marc B Rosenman, Brian R Overholser

Front Cardiovasc Med· December 2022

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Pharmacokinetic modeling of R and S-Methadone and their metabolites to study the effects of various covariates in post-operative children.
Blessed W Aruldhas, Sara K Quinney, Brian R Overholser, Michael A Heathman, Andrea R Masters

CPT Pharmacometrics Syst Pharmacol· October 2021

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The CYP3A5 genotypes of both liver transplant recipients and donors influence the time-dependent recovery of tacrolimus clearance during the early stage following transplantation.
Li Huang, Abdullah A Assiri, Peihao Wen, Kun Zhang, Junwei Fan, Brian R Overholser

Clin Transl Med· October 2021

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A Novel Perioperative Multidose Methadone-Based Multimodal Analgesic Strategy in Children Achieved Safe and Low Analgesic Blood Methadone Levels Enabling Opioid-Sparing Sustained Analgesia With Minimal Adverse Effects.
Senthilkumar Sadhasivam, Blessed W Aruldhas, Senthil Packiasabapathy, Brian R Overholser, Pengyue Zhang

Anesth Analg· August 2021

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Novel associations between polymorphisms, perioperative methadone metabolism and clinical outcomes in children.
Senthil Packiasabapathy, Blessed W Aruldhas, Pengyue Zhang, Brian R Overholser, Sara K Quinney

Pharmacogenomics· July 2021

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Transdermal Testosterone Attenuates Drug-Induced Lengthening of Both Early and Late Ventricular Repolarization in Older Men.
Elena Tomaselli Muensterman, Heather A Jaynes, Kevin M Sowinski, Brian R Overholser, Changyu Shen

Clin Pharmacol Ther· June 2021

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Letrozole targets the human ether-a-go-go-related gene potassium current in glioblastoma.
Tyler Shugg, Nimita Dave, Enoch Amarh, Abdullah A Assiri, Karen E Pollok, Brian R Overholser

Basic Clin Pharmacol Toxicol· March 2021

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Enhanced Response to Drug-Induced QT Interval Lengthening in Patients with Heart Failure with Preserved Ejection Fraction.
James E Tisdale, Heather A Jaynes, Brian R Overholser, Kevin M Sowinski, Mark D Fisch

J Card Fail· September 2020

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Neurohormonal Regulation of I in Heart Failure: Implications for Ventricular Arrhythmogenesis and Sudden Cardiac Death.
Tyler Shugg, Andy Hudmon, Brian R Overholser

J Am Heart Assoc· September 2020

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Ergocalciferol Versus Cholecalciferol in Non-Dialysis Dependent Chronic Kidney Disease Patients: A Small Retrospective Cohort Study.
Akram Al-Makki, Kaitlin Frost, Sang-A Yun, Brian Overholser, Brian Shepler

J Pharm Pharm Sci· August 2020

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Pharmacogenomics of methadone: a narrative review of the literature.
Senthil Packiasabapathy, Blessed W Aruldhas, Nicole Horn, Brian R Overholser, Sara K Quinney

Pharmacogenomics· August 2020

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Inhibition of Human Ether-A-Go-Go-Related Gene (hERG) Potassium Current by the Novel Sotalol Analogue, Soestalol.
Tyler Shugg, John C Somberg, Janos Molnar, Brian R Overholser

JACC Clin Electrophysiol· July 2020

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Progesterone Metabolites Inhibit the Human Ether-a-go-go-Related Gene and Predict QT Interval Length.
Tyler Shugg, Christian Egly, Chris W Stamatkin, Avinash S Patil, James E Tisdale, Brian R Overholser

J Clin Pharmacol· May 2020

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MicroRNA 362-3p Reduces hERG-related Current and Inhibits Breast Cancer Cells Proliferation.
Abdullah A Assiri, Noha Mourad, Minghai Shao, Patrick Kiel, Wanqing Liu, Brian R Overholser

Cancer Genomics Proteomics· March 2020

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Effect of Transdermal Testosterone and Oral Progesterone on Drug-Induced QT Interval Lengthening in Older Men: A Randomized, Double-Blind, Placebo-Controlled Crossover-Design Study.
Elena Tomaselli Muensterman, Heather A Jaynes, Kevin M Sowinski, Brian R Overholser, Changyu Shen

Circulation· September 2019

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Progesterone pretreatment reduces the incidence of drug-induced torsades de pointes in atrioventricular node-ablated isolated perfused rabbit hearts.
James E Tisdale, Heather A Jaynes, Brian R Overholser, Kevin M Sowinski, Richard J Kovacs

J Cardiovasc Electrophysiol· June 2019

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Calcium/calmodulin-dependent protein kinase II regulation of I during sustained β-adrenergic receptor stimulation.
Tyler Shugg, Derrick E Johnson, Minghai Shao, Xianyin Lai, Frank Witzmann, Brian R Overholser

Heart Rhythm· June 2018

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