Publications by authors named "Brian T Edelson"

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Bhlhe40 Coordinates T Cell Programs with Distinct CD4 and CD8 T Cell Requirements for Anti-PD-1 Versus Anti-CTLA-4.
Akata Saha, Tomoyuki Minowa, Alexander S Shavkunov, Avery J Salmon, Sunita Keshari, Brian T Edelson

bioRxiv· October 2025

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HLA-Fc fusion proteins for antigen-specific humoral suppression.
Chang Liu, Hongjie Guo, Brian T Edelson

Hum Immunol· September 2025

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Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression.
Isidoro Cobo, Jessica Murillo-Saich, Mohnish Alishala, Stephen Calderon, Roxana Coras, Brian T Edelson

Immunity· April 2025

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Reprogramming aerobic metabolism mitigates Streptococcus pyogenes tissue damage in a mouse necrotizing skin infection model.
Wei Xu, Tara R Bradstreet, Zongsen Zou, Suzanne Hickerson, Yuan Zhou, Brian T Edelson

Nat Commun· March 2025

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A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populations.
Claudia Cantoni, Roman A Smirnov, Maria Firulyova, Prabhakar S Andhey, Tara R Bradstreet, Brian T Edelson

J Clin Invest· January 2025

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Bhlhe40 Promotes CD4+ T Helper 1 Cell and Suppresses T Follicular Helper Cell Differentiation during Viral Infection.
Christine Nguyen, Matthew Kudek, Ryan Zander, Hongshen Niu, Jian Shen, Brian T Edelson

J Immunol· June 2024

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BHLHE40 Regulates Myeloid Cell Polarization through IL-10-Dependent and -Independent Mechanisms.
Skyler V Hendrix, Yassin Mreyoud, Michael E McNehlan, Asya Smirnov, Sthefany M Chavez, Brian T Edelson

J Immunol· June 2024

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Cutting Edge: STAT4 Promotes Bhlhe40 Induction to Drive Protective IFN-γ from NK Cells during Viral Infection.
Hyunu Kim, Aamna Abbasi, Jessica Sharrock, Endi K Santosa, Sam Sheppard, Brian T Edelson

J Immunol· November 2023

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BHLHE40 Mediates Cross-Talk between Pathogenic TH17 Cells and Myeloid Cells during Experimental Autoimmune Encephalomyelitis.
Melissa E Cook, Irina Shchukina, Chih-Chung Lin, Tara R Bradstreet, Elizabeth A Schwarzkopf, Brian T Edelson

Immunohorizons· November 2023

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Steady-state memory-phenotype conventional CD4 T cells exacerbate autoimmune neuroinflammation in a bystander manner via the Bhlhe40/GM-CSF axis.
Min-Ji Cho, Hong-Gyun Lee, Jae-Won Yoon, Gil-Ran Kim, Ja-Hyun Koo, Brian T Edelson

Exp Mol Med· May 2023

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Antigen-guided depletion of anti-HLA antibody-producing cells by HLA-Fc fusion proteins.
Ashlee M Webber, Tara R Bradstreet, Xiaoli Wang, Hongjie Guo, Christopher A Nelson, Brian T Edelson

Blood· October 2022

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Antigen-specific depletion of CD4 T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity.
Jaeu Yi, Aidan T Miller, Angela S Archambault, Andrew J Jones, Tara R Bradstreet, Brian T Edelson

Sci Immunol· October 2022

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The ZFP36 family of RNA binding proteins regulates homeostatic and autoreactive T cell responses.
Melissa E Cook, Tara R Bradstreet, Ashlee M Webber, Jongshin Kim, Andrea Santeford, Brian T Edelson

Sci Immunol· October 2022

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Mesothelium-Derived Factors Shape GATA6-Positive Large Cavity Macrophages.
Chin-Wen Lai, Prachi Bagadia, Derek A G Barisas, Nicholas N Jarjour, Rachel Wong, Brian T Edelson

J Immunol· August 2022

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BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy.
Avery J Salmon, Alexander S Shavkunov, Qi Miao, Nicholas N Jarjour, Sunita Keshari, Brian T Edelson

Cancer Immunol Res· May 2022

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Standardized Uptake Value for F-Fluorodeoxyglucose Is a Marker of Inflammatory State and Immune Infiltrate in Cervical Cancer.
John M Floberg, Jin Zhang, Naoshad Muhammad, Todd A DeWees, Matthew Inkman, Brian T Edelson

Clin Cancer Res· August 2021

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CD11cCD88CD317 myeloid cells are critical mediators of persistent CNS autoimmunity.
Navid Manouchehri, Rehana Z Hussain, Petra D Cravens, Ekaterina Esaulova, Maxim N Artyomov, Brian T Edelson

Proc Natl Acad Sci U S A· April 2021

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Transcription Factor Bhlhe40 in Immunity and Autoimmunity.
Melissa E Cook, Nicholas N Jarjour, Chih-Chung Lin, Brian T Edelson

Trends Immunol· November 2020

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Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation.
Ekaterina Esaulova, Claudia Cantoni, Irina Shchukina, Konstantin Zaitsev, Robert C Bucelli, Brian T Edelson

Neurol Neuroimmunol Neuroinflamm· July 2020

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Pathogenic Bhlhe40+ GM-CSF+ CD4+ T cells promote indirect alloantigen presentation in the GI tract during GVHD.
Clint Piper, Vivian Zhou, Richard Komorowski, Aniko Szabo, Benjamin Vincent, Brian T Edelson

Blood· February 2020

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BHLHE40 Promotes T2 Cell-Mediated Antihelminth Immunity and Reveals Cooperative CSF2RB Family Cytokines.
Nicholas N Jarjour, Tara R Bradstreet, Elizabeth A Schwarzkopf, Melissa E Cook, Chin-Wen Lai, Brian T Edelson

J Immunol· February 2020

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The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8 T Cell Fitness and Functionality.
Chaofan Li, Bibo Zhu, Young Min Son, Zheng Wang, Li Jiang, Brian T Edelson

Immunity· January 2020

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The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8 T Cell Fitness and Functionality.
Chaofan Li, Bibo Zhu, Young Min Son, Zheng Wang, Li Jiang, Brian T Edelson

Immunity· September 2019

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Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity.
Nan Zhang, Rafael S Czepielewski, Nicholas N Jarjour, Emma C Erlich, Ekaterina Esaulova, Brian T Edelson

J Exp Med· June 2019

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Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity.
Nicholas N Jarjour, Elizabeth A Schwarzkopf, Tara R Bradstreet, Irina Shchukina, Chih-Chung Lin, Brian T Edelson

Nat Immunol· June 2019

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