Publications by authors named "Brigitte Kerfelec"

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Novel single-domain antibodies targeting a unique transferrin receptor 1 epitope for cross-species delivery of drugs in the central nervous system.
Marion David, Romy Cohen, Diane Beuzelin, Géraldine Ferracci, Marina Cresci, Brigitte Kerfelec

J Control Release· December 2025

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Functional targeting of Glypican-4 by a conformation-specific single-domain antibody.
Remi Bonjean, Rossana Cuciniello, Brigitte Kerfelec, Patrick Chames, Rosanna Dono

Biomaterials· November 2025

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Nanobody-enhanced T cell cancer immunotherapy: Advancing precision medicine.
Remy Boisgard, Juliette Prothon, Celia Torrielli, Patrick Chames, Brigitte Kerfelec

Mol Ther· October 2025

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Decoupling Individual Host Response and Immune Cell Engager Cytotoxic Potency.
Cristina Gonzàlez Gutierrez, Adrien Aimard, Martine Biarnes-Pélicot, Brigitte Kerfelec, Pierre-Henri Puech

ACS Nano· January 2025

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Specific Targeting of Mesothelin-Expressing Malignant Cells Using Nanobody-Functionalized Magneto-Fluorescent Nanoassemblies.
Tina Briolay, Judith Fresquet, Damien Meyer, Brigitte Kerfelec, Patrick Chames

Int J Nanomedicine· January 2024

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Rapid nanobody-based imaging of mesothelin expressing malignancies compatible with blocking therapeutic antibodies.
Abdennour Benloucif, Damien Meyer, Laure Balasse, Armelle Goubard, Lucile Danner, Brigitte Kerfelec

Front Immunol· July 2023

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Anti-NKG2D single domain-based antibodies for the modulation of anti-tumor immune response.
Adeline Raynaud, Klervi Desrumeaux, Laurent Vidard, Elise Termine, Daniel Baty, Brigitte Kerfelec

Oncoimmunology· December 2020

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A Bispecific Antibody-Based Approach for Targeting Mesothelin in Triple Negative Breast Cancer.
Joanie Del Bano, Rémy Florès-Florès, Emmanuelle Josselin, Armelle Goubard, Laetitia Ganier, Brigitte Kerfelec

Front Immunol· June 2020

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Nanobody-CD16 Catch Bond Reveals NK Cell Mechanosensitivity.
Cristina González, Patrick Chames, Brigitte Kerfelec, Daniel Baty, Philippe Robert

Biophys J· April 2019

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Preclinical Evaluation of Mesothelin-Specific Ligands for SPECT Imaging of Triple-Negative Breast Cancer.
Christopher Montemagno, Sandrine Bacot, Mitra Ahmadi, Brigitte Kerfelec, Daniel Baty

J Nucl Med· July 2018

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Taking up Cancer Immunotherapy Challenges: Bispecific Antibodies, the Path Forward?
Joanie Del Bano, Patrick Chames, Daniel Baty, Brigitte Kerfelec

Antibodies (Basel)· December 2015

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Anti-Mesothelin Nanobodies for Both Conventional and Nanoparticle-Based Biomedical Applications.
Andrew M Prantner, Marc Turini, Brigitte Kerfelec, Shree Joshi, Daniel Baty

J Biomed Nanotechnol· July 2015

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A FcγRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy.
Marc Turini, Patrick Chames, Pierre Bruhns, Daniel Baty, Brigitte Kerfelec

Oncotarget· July 2014

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Masked selection: a straightforward and flexible approach for the selection of binders against specific epitopes and differentially expressed proteins by phage display.
Klervi Even-Desrumeaux, Damien Nevoltris, Marie Noelle Lavaut, Karima Alim, Jean-Paul Borg, Brigitte Kerfelec

Mol Cell Proteomics· February 2014

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Single-domain antibody-based and linker-free bispecific antibodies targeting FcγRIII induce potent antitumor activity without recruiting regulatory T cells.
Caroline Rozan, Amélie Cornillon, Corinne Pétiard, Martine Chartier, Ghislaine Behar, Brigitte Kerfelec

Mol Cancer Ther· August 2013

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Therapeutic antibodies for the treatment of pancreatic cancer.
Patrick Chames, Brigitte Kerfelec, Daniel Baty

ScientificWorldJournal· June 2010

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Modification of pancreatic lipase properties by directed molecular evolution.
Damien Yann Colin, Paule Deprez-Beauclair, Noella Silva, Lourdes Infantes, Brigitte Kerfelec

Protein Eng Des Sel· May 2010

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Computational study of colipase interaction with lipid droplets and bile salt micelles.
Brigitte Kerfelec, Maya Allouche, Damien Colin, Marie Hélène Van Eyck, Robert Brasseur

Proteins· December 2008

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Exploring the active site cavity of human pancreatic lipase.
Damien Yann Colin, Paule Deprez-Beauclair, Maya Allouche, Robert Brasseur, Brigitte Kerfelec

Biochem Biophys Res Commun· June 2008

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Structure and orientation of pancreatic colipase in a lipid environment: PM-IRRAS and Brewster angle microscopy studies.
Maya Allouche, Sabine Castano, Damien Colin, Bernard Desbat, Brigitte Kerfelec

Biochemistry· December 2007

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Role of the lid hydrophobicity pattern in pancreatic lipase activity.
Annick Thomas, Maya Allouche, Frédéric Basyn, Robert Brasseur, Brigitte Kerfelec

J Biol Chem· December 2005

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Time-resolved fluorescence allows selective monitoring of Trp30 environmental changes in the seven-Trp-containing human pancreatic lipase.
Paul Ramos, Thierry Coste, Etienne Piémont, Jean Marc Lessinger, Jean Alain Bousquet, Brigitte Kerfelec

Biochemistry· November 2003

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Activation of horse PLRP2 by bile salts does not require colipase.
Sandrine Jayne, Brigitte Kerfelec, Edith Foglizzo, Simone Granon, Juan Hermoso

Biochemistry· July 2002

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High expression in adult horse of PLRP2 displaying a low phospholipase activity.
Sandrine Jayne, Brigitte Kerfelec, Edith Foglizzo, Catherine Chapus, Isabelle Crenon

Biochim Biophys Acta· February 2002

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