Publications by authors named "Brigitte Laforest"

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Coordinated transcriptional control of the adult ventricular conduction system.
Ozanna Burnicka-Turek, Katy A Trampel, Brigitte Laforest, Michael T Broman, Xinan H Yang

Elife· July 2025

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Coordinated transcriptional control of the adult ventricular conduction system.
Ozanna Burnicka-Turek, Katy A Trampel, Brigitte Laforest, Michael T Broman, Xinan H Yang

bioRxiv· February 2025

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Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948.
Kevin J Filipski, Luis A Martinez-Alsina, Matthew R Reese, Edelweiss Evrard, Leanne M Buzon, Brigitte Laforest

J Med Chem· February 2025

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Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice.
Atsuki En, Hanumakumar Bogireddi, Briana Thomas, Alexis V Stutzman, Sachie Ikegami, Brigitte LaForest

Cell Rep· June 2024

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Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice.
Atsuki En, Hanumakumar Bogireddi, Briana Thomas, Alexis Stutzman, Sachie Ikegami, Brigitte LaForest

bioRxiv· April 2024

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A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.
Michael T Broman, Rangarajan D Nadadur, Carlos Perez-Cervantes, Ozanna Burnicka-Turek, Sonja Lazarevic, Brigitte Laforest

Circulation· April 2024

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Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.
Rachel J Roth Flach, Eliza Bollinger, Allan R Reyes, Brigitte Laforest, Bethany L Kormos

Nat Commun· August 2023

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Partial and complete loss of myosin binding protein H-like cause cardiac conduction defects.
David Y Barefield, Sean Yamakawa, Ibrahim Tahtah, Jordan J Sell, Michael Broman, Brigitte Laforest

J Mol Cell Cardiol· August 2022

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-dependent coordination of mouse cardiac progenitor cell patterning and differentiation.
Sonia Stefanovic, Brigitte Laforest, Jean-Pierre Desvignes, Fabienne Lescroart, Laurent Argiro

Elife· August 2020

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ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
Wenli Dai, Rangarajan D Nadadur, Jaclyn A Brennan, Heather L Smith, Kaitlyn M Shen, Brigitte Laforest

Circ Res· July 2020

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Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis.
Brigitte Laforest, Wenli Dai, Leonid Tyan, Sonja Lazarevic, Kaitlyn M Shen

J Clin Invest· November 2019

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A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice.
Wenli Dai, Brigitte Laforest, Leonid Tyan, Kaitlyn M Shen, Rangarajan D Nadadur

Elife· March 2019

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Hoxa1 and Hoxb1 are required for pharyngeal arch artery development.
Marine Roux, Brigitte Laforest, Nathalie Eudes, Nicolas Bertrand, Sonia Stefanovic

Mech Dev· February 2017

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Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development.
Marine Roux, Brigitte Laforest, Mario Capecchi, Nicolas Bertrand, Stéphane Zaffran

Dev Biol· October 2015

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Genetic lineage tracing analysis of anterior Hox expressing cells.
Brigitte Laforest, Nicolas Bertrand, Stéphane Zaffran

Methods Mol Biol· May 2015

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EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner.
Cai-Xia Ma, Yang-Liu Song, Liyun Xiao, Li-Xiang Xue, Wen-Juan Li, Brigitte Laforest

Cell Mol Life Sci· May 2015

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Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart.
M Sameer Rana, Magali Théveniau-Ruissy, Christopher De Bono, Karim Mesbah, Alexandre Francou, Brigitte Laforest

Circ Res· October 2014

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Genetic insights into bicuspid aortic valve formation.
Brigitte Laforest, Mona Nemer

Cardiol Res Pract· August 2012

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GATA5 interacts with GATA4 and GATA6 in outflow tract development.
Brigitte Laforest, Mona Nemer

Dev Biol· October 2011

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Loss of Gata5 in mice leads to bicuspid aortic valve.
Brigitte Laforest, Gregor Andelfinger, Mona Nemer

J Clin Invest· July 2011

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A hand for the epicardium.
Brigitte Laforest, Mona Nemer

Circ Res· April 2011

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An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation.
Mathieu Nadeau, Romain O Georges, Brigitte Laforest, Abir Yamak, Chantal Lefebvre

Proc Natl Acad Sci U S A· November 2010

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