Publications by authors named "Brooke Prinzing"

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Computational structural optimization enhances IL13Rα2 - B7-H3 tandem CAR T cells to overcome antigen-heterogeneity-mediated tumor escape.
Michaela M Meehl, Kalyan Immadisetty, Vikas D Trivedi, Pawel Glowacki, Brooke Prinzing

Mol Ther· October 2025

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LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy.
Sunny Mai, Alan Hodges, Hui-Ming Chen, Jilu Zhang, Yi-Ling Wang, Brooke Prinzing

Cancer Res· December 2023

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RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
Julia Carnevale, Eric Shifrut, Nupura Kale, William A Nyberg, Franziska Blaeschke, Brooke Prinzing

Nature· September 2022

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Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity.
Brooke Prinzing, Caitlin C Zebley, Christopher T Petersen, Yiping Fan, Alejandro Allo Anido

Sci Transl Med· November 2021

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Hypoxia-inducible CAR expression: An answer to the on-target/off-tumor dilemma?
Brooke Prinzing, Giedre Krenciute

Cell Rep Med· April 2021

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MyD88/CD40 signaling retains CAR T cells in a less differentiated state.
Brooke Prinzing, Patrick Schreiner, Matthew Bell, Yiping Fan, Giedre Krenciute

JCI Insight· November 2020

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Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma.
Zhongzhen Yi, Brooke L Prinzing, Felicia Cao, Stephen Gottschalk, Giedre Krenciute

Mol Ther Methods Clin Dev· June 2018

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CAR T-cell therapy for glioblastoma: ready for the next round of clinical testing?
Brooke L Prinzing, Stephen M Gottschalk, Giedre Krenciute

Expert Rev Anticancer Ther· May 2018

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Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants.
Giedre Krenciute, Brooke L Prinzing, Zhongzhen Yi, Meng-Fen Wu, Hao Liu

Cancer Immunol Res· July 2017

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