Publications by authors named "Bruce Freeman"

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Nitroalkene inhibition of pro-inflammatory macrophage effector function via modulation of signaling metabolite levels.
Emily R Stevenson, James P O'Brien, Allison M Manuel, Crystal E Uvalle, Gregory J Buchan, Bruce A Freeman

Front Physiol· November 2025

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Endothelial CYB5R1 is a Coenzyme Q reductase that suppresses ferroptosis and atherosclerosis.
Robert Hall, Svetlana Samovich, Mate Katona, Shuai Yuan, Megan P Miller, Bruce A Freeman

Res Sq· September 2025

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Fatty acid nitroalkenes regulate intestinal lipid absorption.
Francisco J Schopfer, Lihong Teng, Ahssan Sekandari, Ese S Ekhator, Alison B Kohan, Bruce A Freeman

J Lipid Res· August 2025

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Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry.
Nils Helge Schebb, Nadja Kampschulte, Gerhard Hagn, Kathrin Plitzko, Sven W Meckelmann, Bruce Freeman

Sci Signal· May 2025

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Nitro-oleic acid enhances mitochondrial metabolism and ameliorates heart failure with preserved ejection fraction in mice.
Marion Müller, Torben Schubert, Cornelius Welke, Tibor Maske, Thomas Patschkowski, Bruce A Freeman

Nat Commun· April 2025

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Chemoproteomic analysis reveals RECQL4 as a mediator of nitroalkene-dependent double-strand break repair inhibition in cancer.
Dennis C Braden, Mostafa A L Adbel-Salam, Alparslan Asan, John Skoko, Huiming Lu, Bruce A Freeman

Res Sq· March 2025

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Lipoxin A yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling.
Adolf Koudelka, Gregory J Buchan, Veronika Cechova, James P O'Brien, Emily R Stevenson, Bruce A Freeman

J Lipid Res· January 2025

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Lipoxin A yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling.
Adolf Koudelka, Gregory J Buchan, Veronika Cechova, James P O'Brien, Heng Liu, Bruce A Freeman

bioRxiv· February 2024

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Fatty acid nitroalkenes - Multi-target agents for the treatment of sickle cell disease.
Fabliha A Chowdhury, Nicole Colussi, Malini Sharma, Katherine C Wood, Julia Z Xu, Bruce A Freeman

Redox Biol· December 2023

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Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples.
Valerie B O'Donnell, Nils H Schebb, Ginger L Milne, Michael P Murphy, Christopher P Thomas, Bruce A Freeman

Nat Commun· November 2023

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Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Lisa Hong, Dennis C Braden, Yaoning Zhao, John J Skoko, Fei Chang, Bruce A Freeman

Redox Biol· October 2023

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Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Lisa Hong, Dennis C Braden, Yaoning Zhao, John J Skoko, Fei Chang, Bruce A Freeman

bioRxiv· August 2023

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Meta-omics profiling of the gut-lung axis illuminates metabolic networks and host-microbial interactions associated with elevated lung elastance in a murine model of obese allergic asthma.
Victoria A Heinrich, Crystal Uvalle, Michelle L Manni, Kelvin Li, Steven J Mullett, Bruce A Freeman

Front Microbiomes· May 2023

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Neuroprotective actions of a fatty acid nitroalkene in Parkinson's disease.
Roberto Di Maio, Matthew T Keeney, Veronika Cechova, Amanda Mortimer, Ahssan Sekandari, Bruce A Freeman

NPJ Parkinsons Dis· April 2023

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Assessment of Concordance between Chairside Ultrasonography and Digital Palpation in Detecting Myofascial Trigger Points in Masticatory Myofascial Pain Syndrome.
Mohamed Elbarbary, Michael Goldberg, Howard C Tenenbaum, David K Lam, Bruce V Freeman

J Endod· February 2023

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Nitro-oleic acid reduces thoracic aortic aneurysm progression in a mouse model of Marfan syndrome.
Felix Sebastian Nettersheim, Julian Lemties, Simon Braumann, Simon Geißen, Senai Bokredenghel, Bruce A Freeman

Cardiovasc Res· July 2022

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Immunomodulatory actions of a kynurenine-derived endogenous electrophile.
Mara Carreño, Maria F Pires, Steven R Woodcock, Tomasz Brzoska, Samit Ghosh, Bruce A Freeman

Sci Adv· July 2022

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Fatty acid nitroalkene reversal of established lung fibrosis.
Adolf Koudelka, Veronika Cechova, Mauricio Rojas, Nilay Mitash, Anna Bondonese, Bruce A Freeman

Redox Biol· April 2022

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Lipid nitroalkene nanoparticles for the focal treatment of ischemia reperfusion.
Gary Z Yu, Thiruganesh Ramasamy, Marco Fazzari, Xucai Chen, Bruce Freeman

Nanotheranostics· March 2022

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Masticatory Myofascial Pain Syndrome: Implications for Endodontists.
Mohamed Elbarbary, Ariel Oren, Michael Goldberg, Bruce V Freeman, David Mock

J Endod· January 2022

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Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma.
Michelle L Manni, Victoria A Heinrich, Gregory J Buchan, James P O'Brien, Crystal Uvalle, Bruce A Freeman

Sci Rep· September 2021

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Nitro-Oleic Acid (NO-OA) Improves Systolic Function in Dilated Cardiomyopathy by Attenuating Myocardial Fibrosis.
Simon Braumann, Wibke Schumacher, Nam Gyu Im, Felix Sebastian Nettersheim, Dennis Mehrkens, Bruce A Freeman

Int J Mol Sci· August 2021

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Electrophilic nitro-fatty acids suppress psoriasiform dermatitis: STAT3 inhibition as a contributory mechanism.
Peng Wang, Meaghan E Killeen, Tina L Sumpter, Laura K Ferris, Louis D Falo, Bruce A Freeman

Redox Biol· July 2021

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TRP Channel Agonists Activate Different Afferent Neuromodulatory Mechanisms in Guinea Pig Urinary Bladder.
Stephanie L Daugherty, Jonathan M Beckel, Kyoungeun A Kim, Bruce A Freeman, Jiaxin Liu

Front Physiol· June 2021

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Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO) and nitroalkene (RNO) substituents.
Marco Fazzari, Steven R Woodcock, Pascal Rowart, Karina Ricart, Jack R Lancaster, Bruce A Freeman

Redox Biol· May 2021

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