Publications by authors named "Bruce Fulton"

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Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia.
Raji E Joseph, Thomas E Wales, Sandrine Jayne, Robert G Britton, D Bruce Fulton

Elife· December 2024

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Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia.
Raji E Joseph, Thomas E Wales, Sandrine Jayne, Robert G Britton, D Bruce Fulton

bioRxiv· October 2024

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The Conformational State of the BTK Substrate PLCγ Contributes to Ibrutinib Resistance.
Raji E Joseph, Jacques Lowe, D Bruce Fulton, John R Engen, Thomas E Wales

J Mol Biol· March 2022

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MbnC Is Not Required for the Formation of the N-Terminal Oxazolone in the Methanobactin from Methylosinus trichosporium OB3b.
Philip Dershwitz, Wenyu Gu, Julien Roche, Christina S Kang-Yun, Jeremy D Semrau, Bruce Fulton

Appl Environ Microbiol· January 2022

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Differential impact of BTK active site inhibitors on the conformational state of full-length BTK.
Raji E Joseph, Neha Amatya, D Bruce Fulton, John R Engen, Thomas E Wales

Elife· November 2020

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The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein.
Thorny Cesilie Bie Andersen, Per Eugen Kristiansen, Zsuzsa Huszenicza, Maria U Johansson, Ramakrishna Prabhu Gopalakrishnan, D Bruce Fulton

J Biol Chem· October 2019

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Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases.
Neha Amatya, Thomas E Wales, Annie Kwon, Wayland Yeung, Raji E Joseph, D Bruce Fulton

Proc Natl Acad Sci U S A· October 2019

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Achieving a Graded Immune Response: BTK Adopts a Range of Active/Inactive Conformations Dictated by Multiple Interdomain Contacts.
Raji E Joseph, Thomas E Wales, D Bruce Fulton, John R Engen, Amy H Andreotti

Structure· October 2017

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An Autoinhibitory Role for the Pleckstrin Homology Domain of Interleukin-2-Inducible Tyrosine Kinase and Its Interplay with Canonical Phospholipid Recognition.
Sujan Devkota, Raji E Joseph, Scott E Boyken, D Bruce Fulton, Amy H Andreotti

Biochemistry· June 2017

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Electron self-exchange in hemoglobins revealed by deutero-hemin substitution.
Navjot Singh Athwal, Jagannathan Alagurajan, Ryan Sturms, D Bruce Fulton, Amy H Andreotti

J Inorg Biochem· September 2015

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Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation.
Sujan Devkota, Raji E Joseph, Lie Min, D Bruce Fulton, Amy H Andreotti

J Mol Biol· August 2015

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Defining a two-pronged structural model for PB1 (Phox/Bem1p) domain interaction in plant auxin responses.
David A Korasick, Srirupa Chatterjee, Marco Tonelli, Hesam Dashti, Soon Goo Lee, D Bruce Fulton

J Biol Chem· May 2015

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A selective NMR probe to monitor the conformational transition from inactive to active kinase.
Qian Xie, D Bruce Fulton, Amy H Andreotti

ACS Chem Biol· January 2015

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A conserved isoleucine maintains the inactive state of Bruton's tyrosine kinase.
Scott E Boyken, Nikita Chopra, Qian Xie, Raji E Joseph, Thomas E Wales, D Bruce Fulton

J Mol Biol· October 2014

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An adaptable pentaloop defines a robust neomycin-B RNA aptamer with conditional ligand-bound structures.
Muslum Ilgu, D Bruce Fulton, Ragothaman M Yennamalli, Monica H Lamm, Taner Z Sen

RNA· June 2014

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Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases.
Raji E Joseph, Iivari Kleino, Thomas E Wales, Qian Xie, D Bruce Fulton

Sci Signal· August 2013

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Substrate recognition of PLCγ1 via a specific docking surface on Itk.
Qian Xie, Raji E Joseph, D Bruce Fulton, Amy H Andreotti

J Mol Biol· February 2013

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Rescue of the aggregation prone Itk Pleckstrin Homology domain by two mutations derived from the related kinases, Btk and Tec.
Scott E Boyken, D Bruce Fulton, Amy H Andreotti

Protein Sci· September 2012

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Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures.
Raji E Joseph, Nathaniel D Ginder, Julie A Hoy, Jay C Nix, D Bruce Fulton

Acta Crystallogr Sect F Struct Biol Cryst Commun· February 2012

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Hydroxylamine reduction to ammonium by plant and cyanobacterial hemoglobins.
Ryan Sturms, Alan A DiSpirito, D Bruce Fulton, Mark S Hargrove

Biochemistry· December 2011

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Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals.
Dana Morrone, Matthew L Hillwig, Matthew E Mead, Luke Lowry, D Bruce Fulton

Biochem J· May 2011

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Comparison of the dielectric response obtained from fluorescence upconversion measurements and molecular dynamics simulations for coumarin 153-apomyoglobin complexes and structural analysis of the complexes by NMR and fluorescence methods.
Sayantan Bose, Ramkrishna Adhikary, Charles A Barnes, D Bruce Fulton, Mark S Hargrove

J Phys Chem A· April 2011

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Concerted C-N and C-H bond formation in a magnesium-catalyzed hydroamination.
James F Dunne, D Bruce Fulton, Arkady Ellern, Aaron D Sadow

J Am Chem Soc· December 2010

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Enzymatic synthesis of L-DOPA alpha-glycosides by reaction with sucrose catalyzed by four different glucansucrases from four strains of Leuconostoc mesenteroides.
Seung-Heon Yoon, D Bruce Fulton, John F Robyt

Carbohydr Res· August 2010

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Disrupting the intermolecular self-association of Itk enhances T cell signaling.
Lie Min, Wenfang Wu, Raji E Joseph, D Bruce Fulton, Leslie Berg

J Immunol· April 2010

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