Publications by authors named "Bruce Jacobson"

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Quantifying NF-κB Activation by Flow Cytometry of IκBα Degradation.
Praveen Krishna Veerasubramanian, Bruce A Jacobson, Fridrik J Karlsson, Jennifer L Duffen

Curr Protoc· May 2024

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The Interleukin-1 Receptor-Associated Kinase 4 Inhibitor PF-06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial.
Aaron Winkler, Weiyong Sun, Saurav De, Aiping Jiao, M Nusrat Sharif, Bruce A Jacobson

Arthritis Rheumatol· December 2021

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Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold.
Scott A Bolton, James C Sutton, Rushith Anumula, Gregory S Bisacchi, Bruce Jacobson

Bioorg Med Chem Lett· September 2013

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Human alveolar macrophage gene responses to Mycobacterium tuberculosis strains H37Ra and H37Rv.
Richard F Silver, Jessica Walrath, Hung Lee, Bruce A Jacobson, Heidi Horton

Am J Respir Cell Mol Biol· April 2009

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A multienzyme bioluminescent time-resolved pyrophosphate assay.
Ye Sun, K Bruce Jacobson, Val Golovlev

Anal Biochem· August 2007

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Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP).
Richard Sulsky, David R Magnin, Yanting Huang, Ligaya Simpkins, Prakash Taunk, Bruce L Jacobson

Bioorg Med Chem Lett· June 2007

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IL-13 blockade reduces lung inflammation after Ascaris suum challenge in cynomolgus monkeys.
Andrea Bree, Franklin J Schlerman, Michael Wadanoli, Lioudmila Tchistiakova, Kimberly Marquette, Bruce A Jacobson

J Allergy Clin Immunol· May 2007

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Structure of the complex of trypsin with a highly potent synthetic inhibitor at 0.97 A resolution.
Manashi Sherawat, Punit Kaur, Markus Perbandt, Christian Betzel, William A Slusarchyk, Bruce L Jacobson

Acta Crystallogr D Biol Crystallogr· April 2007

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Efficacy of IL-13 neutralization in a sheep model of experimental asthma.
Marion T Kasaian, Debra D Donaldson, Lioudmila Tchistiakova, Kimberly Marquette, Xiang-Yang Tan, Bruce A Jacobson

Am J Respir Cell Mol Biol· March 2007

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Novel transparent nano- to micro-heterogeneous substrates for in-situ cell migration study.
Irene Y Tsai, J Angelo Green, Masahiro Kimura, Bruce Jacobson, Thomas P Russell

J Biomed Mater Res A· February 2007

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Label-free detection of biomolecules on microarrays using surface-colloid interaction.
Ye Sun, K Bruce Jacobson, Val Golovlev

Anal Biochem· February 2007

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Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase.
Mark D Wittman, Balu Balasubramanian, Karen Stoffan, Upender Velaparthi, Pieying Liu, Bruce Jacobson

Bioorg Med Chem Lett· February 2007

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Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity.
Mark Wittman, Joan Carboni, Ricardo Attar, Balu Balasubramanian, Praveen Balimane, Bruce Jacobson

J Med Chem· September 2005

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Fibroblast adhesion to micro- and nano-heterogeneous topography using diblock copolymers and homopolymers.
Irene Y Tsai, Masahiro Kimura, Rebecca Stockton, J Angelo Green, Ricardo Puig, Bruce Jacobson

J Biomed Mater Res A· December 2004

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5-lipoxygenase and cyclooxygenase regulate wound closure in NIH/3T3 fibroblast monolayers.
J Angelo Green, Rebecca A Stockton, Christopher Johnson, Bruce S Jacobson

Am J Physiol Cell Physiol· August 2004

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Tumor cells secreting IL-13 but not IL-13Ralpha2 fusion protein have reduced tumorigenicity in vivo.
Hak-Ling Ma, Matthew J Whitters, Bruce A Jacobson, Deborah D Donaldson, Mary Collins

Int Immunol· July 2004

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Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors.
James C Sutton, Scott A Bolton, Malcolm E Davis, Karen S Hartl, Bruce Jacobson

Bioorg Med Chem Lett· May 2004

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A promise not kept.
Bruce K Jacobson

Pharos Alpha Omega Alpha Honor Med Soc· October 2003

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Cyclooxygenase and cAMP-dependent protein kinase reorganize the actin cytoskeleton for motility in HeLa cells.
Honor L Glenn, Bruce S Jacobson

Cell Motil Cytoskeleton· August 2003

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Cdc42 and RhoA are differentially regulated during arachidonate-mediated HeLa cell adhesion.
Louis A Roberts, Honor Glenn, Chang S Hahn, Bruce S Jacobson

J Cell Physiol· July 2003

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Regulation of cell-substrate adhesion by the lipoxygenase and cyclooxygenase branches of arachidonic acid metabolism.
Louis A Roberts, Honor L Glenn, Rebecca A Whitfield, Bruce S Jacobson

Adv Exp Med Biol· May 2003

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Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response.
Monica G Chiaramonte, Margaret Mentink-Kane, Bruce A Jacobson, Allen W Cheever, Matthew J Whitters

J Exp Med· March 2003

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Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2.
Nancy Wood, Matthew J Whitters, Bruce A Jacobson, JoAnn Witek, Joseph P Sypek

J Exp Med· March 2003

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Arachidonic acid signaling to the cytoskeleton: the role of cyclooxygenase and cyclic AMP-dependent protein kinase in actin bundling.
Honor L Glenn, Bruce S Jacobson

Cell Motil Cytoskeleton· November 2002

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