Publications by authors named "Bruce Light"

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Culture-Negative Septic Shock Compared With Culture-Positive Septic Shock: A Retrospective Cohort Study.
Shravan Kethireddy, Beliz Bilgili, Amanda Sees, H Lester Kirchner, Uchenna R Ofoma, R Bruce Light

Crit Care Med· April 2018

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Time required to initiate outbreak and pandemic observational research.
Asgar H Rishu, Nicole Marinoff, Lisa Julien, Mariana Dumitrascu, Nicole Marten, Bruce Light

J Crit Care· August 2017

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Global research preparedness for outbreak-related critical illness.
Robert Fowler, Asgar Rishu, Nicole Marinoff, Lisa Julien, Mariana Dumitrascu, Bruce Light

J Crit Care· August 2017

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Influenza A (H1N1pdm09)-Related Critical Illness and Mortality in Mexico and Canada, 2014.
Guillermo Dominguez-Cherit, Alethse De la Torre, Asgar Rishu, Ruxandra Pinto, Silvio A Ñamendys-Silva, Bruce Light

Crit Care Med· October 2016

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Management and Outcomes of Acute Respiratory Distress Syndrome Caused by Blastomycosis: A Retrospective Case Series.
Ilan S Schwartz, John M Embil, Atul Sharma, Stephen Goulet, R Bruce Light

Medicine (Baltimore)· May 2016

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Extracorporeal membrane oxygenation for blastomycosis-related acute respiratory distress syndrome: a case series.
Joseph M Bednarczyk, Shravan Kethireddy, Christopher W White, Darren H Freed, Rohit K Singal, Bruce Light

Can J Anaesth· July 2015

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Mycobacterium tuberculosis septic shock.
Shravan Kethireddy, R Bruce Light, Yazdan Mirzanejad, Dennis Maki, Yaseen Arabi

Chest· August 2013

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Risk factors for acquisition of endemic blastomycosis.
Maxym Choptiany, Lyle Wiebe, Bill Limerick, Pete Sarsfield, Mary Cheang, Bruce Light

Can J Infect Dis Med Microbiol· July 2011

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Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: a propensity-matched analysis.
Anand Kumar, Ryan Zarychanski, Bruce Light, Joseph Parrillo, Dennis Maki

Crit Care Med· September 2010

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Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock.
Anand Kumar, Paul Ellis, Yaseen Arabi, Dan Roberts, Bruce Light

Chest· November 2009

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Lysozyme, a mediator of sepsis that intrinsically generates hydrogen peroxide to cause cardiovascular dysfunction.
Steven N Mink, Hans Jacobs, Zhao-Qin Cheng, Krika Kasian, Luis E Santos-Martinez, R Bruce Light

Am J Physiol Heart Circ Physiol· September 2009

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Clinical characteristics and outcomes in patients with pulmonary blastomycosis.
Doug Kralt, Bruce Light, Mary Cheang, Tracy MacNair, Lyle Wiebe

Mycopathologia· March 2009

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Plagues in the ICU: a brief history of community-acquired epidemic and endemic transmissible infections leading to intensive care admission.
R Bruce Light

Crit Care Clin· January 2009

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Seasonal variations in the clinical presentation of pulmonary and extrapulmonary blastomycosis.
R Bruce Light, Doug Kralt, John M Embil, Elly Trepman, Lyle Wiebe

Med Mycol· December 2008

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N,N'-diacetylchitobiose, an inhibitor of lysozyme, reverses myocardial depression and lessens norepinephrine requirements in Escherichia coli sepsis in dogs.
Steven N Mink, Krika Kasian, Hans Jacobs, Zhao-Qin Cheng, R Bruce Light

Shock· June 2008

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Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation.
Steven N Mink, Krika Kasian, Luis E Santos Martinez, Hans Jacobs, Ratna Bose, R Bruce Light

Am J Physiol Heart Circ Physiol· April 2008

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Clinical practice guidelines for hospital-acquired pneumonia and ventilator-associated pneumonia in adults.
Coleman Rotstein, Gerald Evans, Abraham Born, Ronald Grossman, R Bruce Light

Can J Infect Dis Med Microbiol· January 2008

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Lysozyme, a mediator of sepsis, impairs the cardiac neural adrenergic response by nonendothelial release of NO and inhibitory G protein signaling.
Steven N Mink, Zhao-Qin Cheng, Ratna Bose, Hans Jacobs, Krika Kasian, R Bruce Light

Am J Physiol Heart Circ Physiol· November 2007

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Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.
Anand Kumar, Daniel Roberts, Kenneth E Wood, Bruce Light, Joseph E Parrillo

Crit Care Med· June 2006

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Lysozyme binding to endocardial endothelium mediates myocardial depression by the nitric oxide guanosine 3',5' monophosphate pathway in sepsis.
Steven N Mink, Ratna Bose, Diane E Roberts, Hans Jacobs, Krika Duke, R Bruce Light

J Mol Cell Cardiol· October 2005

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Inhaled nitric oxide treatment of patients with pulmonary tuberculosis evidenced by positive sputum smears.
Richard Long, Richard Jones, James Talbot, Irvin Mayers, James Barrie, Bruce Light

Antimicrob Agents Chemother· March 2005

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Characterization of membrane N-glycan binding sites of lysozyme for cardiac depression in sepsis.
Hans Jacobs, Steven N Mink, Krika Duke, Deepak Bose, Zhao-Qin Cheng, R Bruce Light

Intensive Care Med· January 2005

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N,N',N"-triacetylglucosamine, an inhibitor of lysozyme, prevents myocardial depression in Escherichia coli sepsis in dogs.
Steven N Mink, Hans Jacobs, Krika Duke, Deepak Bose, Zhao-Qin Cheng, R Bruce Light

Crit Care Med· January 2004

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The clinical evaluation committee in a large multicenter phase 3 trial of drotrecogin alfa (activated) in patients with severe sepsis (PROWESS): role, methodology, and results.
Jean-François Dhainaut, Pierre-François Laterre, Steven P LaRosa, Howard Levy, Gary E Garber, R Bruce Light

Crit Care Med· September 2003

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Guidance on patient identification and administration of recombinant human activated protein C for the treatment of severe sepsis.
Gary Garber, Rt Noel Gibney, Bruce Light, Claudio Martin, Kenneth Cunningham

Can J Infect Dis· November 2002

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