Publications by authors named "Bruce Stillman"

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Genome sequence assembly and annotation of and strains of .
Narges Zali, Osama El Demerdash, Kapeel Chougule, Zhenyuan Lu, Doreen Ware, Bruce Stillman

NAR Genom Bioinform· December 2025

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Mechanisms for licensing origins of DNA replication in eukaryotic cells.
Bruce Stillman, John F X Diffley, Janet H Iwasa

Nat Struct Mol Biol· July 2025

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Establishing a biochemical understanding of the initiation of chromosome replication in bacteria.
Bruce Stillman

Proc Natl Acad Sci U S A· June 2024

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Origins of DNA replication in eukaryotes.
Yixin Hu, Bruce Stillman

Mol Cell· February 2023

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Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters.
Yi-Jun Sheu, Risa Karakida Kawaguchi, Jesse Gillis, Bruce Stillman

Elife· December 2022

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The remarkable gymnastics of ORC.
Bruce Stillman

Elife· February 2022

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The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Xiang Feng, Yasunori Noguchi, Marta Barbon, Bruce Stillman, Christian Speck

Nat Commun· June 2021

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Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication.
Manzar Hossain, Kuhulika Bhalla, Bruce Stillman

Mol Cell· May 2021

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The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure.
Hsiang-Chen Chou, Kuhulika Bhalla, Osama El Demerdesh, Olaf Klingbeil, Kaarina Hanington, Bruce Stillman

Elife· February 2021

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The dynamic nature of the human origin recognition complex revealed through five cryoEM structures.
Matt J Jaremko, Kin Fan On, Dennis R Thomas, Bruce Stillman, Leemor Joshua-Tor

Elife· August 2020

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Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Zuanning Yuan, Sarah Schneider, Thomas Dodd, Alberto Riera, Lin Bai, Bruce Stillman

Proc Natl Acad Sci U S A· July 2020

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The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592.
Elisa Tramentozzi, Paola Ferraro, Manzar Hossain, Bruce Stillman, Vera Bianchi

Cell Cycle· December 2019

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Increasing gender diversity in the STEM research workforce.
Carol W Greider, Jason M Sheltzer, Nancy C Cantalupo, Wilbert B Copeland, Nilanjana Dasgupta, Bruce Stillman

Science· November 2019

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Joseph F. Sambrook (1939-2019).
Ashley Dunn, Ricky W Johnstone, Bruce Stillman

Nat Struct Mol Biol· October 2019

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A structural view of the initiators for chromosome replication.
Kin Fan On, Matt Jaremko, Bruce Stillman, Leemor Joshua-Tor

Curr Opin Struct Biol· December 2018

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Histone Modifications: Insights into Their Influence on Gene Expression.
Bruce Stillman

Cell· September 2018

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Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.
Yasunori Noguchi, Zuanning Yuan, Lin Bai, Sarah Schneider, Gongpu Zhao, Bruce Stillman

Proc Natl Acad Sci U S A· November 2017

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Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
Zuanning Yuan, Alberto Riera, Lin Bai, Jingchuan Sun, Saikat Nandi, Bruce Stillman

Nat Struct Mol Biol· March 2017

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Structure of the active form of human origin recognition complex and its ATPase motor module.
Ante Tocilj, Kin Fan On, Zuanning Yuan, Jingchuan Sun, Elad Elkayam, Bruce Stillman

Elife· January 2017

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Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model.
Jennifer A MacDiarmid, Veronika Langova, Dale Bailey, Scott T Pattison, Stacey L Pattison, Bruce Stillman

PLoS One· August 2016

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Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription.
Manzar Hossain, Bruce Stillman

Elife· July 2016

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Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression.
Yi-Jun Sheu, Justin B Kinney, Bruce Stillman

Genome Res· March 2016

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Reconsidering DNA Polymerases at the Replication Fork in Eukaryotes.
Bruce Stillman

Mol Cell· July 2015

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Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells.
Nihan Kara, Manzar Hossain, Supriya G Prasanth, Bruce Stillman

J Biol Chem· May 2015

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Rhabdomyosarcoma: current challenges and their implications for developing therapies.
Simone Hettmer, Zhizhong Li, Andrew N Billin, Frederic G Barr, D D W Cornelison, Bruce Stillman

Cold Spring Harb Perspect Med· November 2014

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