Publications by authors named "Bruna Paulsen"

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Ovarian support cell in-vitro maturation results in healthy murine live births with no evidence of reprotoxicology in a multigenerational study.
Maria Marchante, Ferran Barrachina, Enric Mestres, Monica Acacio, Kathryn S Potts, Bruna Paulsen

Reprod Biomed Online· June 2025

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Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer.
Vamsi Mangena, Rony Chanoch-Myers, Rafaela Sartore, Bruna Paulsen, Simon Gritsch

Cancer Discov· February 2025

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Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes.
Bruna Paulsen, Sabrina Piechota, Ferran Barrachina, Alexa Giovannini, Simone Kats

J Assist Reprod Genet· August 2024

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Donor side effects experienced under minimal controlled ovarian stimulation with in vitro maturation vs. conventional controlled ovarian stimulation for in vitro fertilization treatment.
Maria Marchante, Ferran Barrachina, Sabrina Piechota, Marta Fernandez-González, Alexa Giovannini, Bruna Paulsen

F S Sci· August 2024

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Human-induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation.
Sabrina Piechota, Maria Marchante, Alexa Giovannini, Bruna Paulsen, Kathryn S Potts

Hum Reprod· December 2023

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Cell-type specific defects in PTEN-mutant cortical organoids converge on abnormal circuit activity.
Martina Pigoni, Ana Uzquiano, Bruna Paulsen, Amanda J Kedaigle, Sung Min Yang

Hum Mol Genet· September 2023

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How collaboration between bioethicists and neuroscientists can advance research.
Insoo Hyun, J C Scharf-Deering, Sarah Sullivan, John Dennis Aach, Paola Arlotta, Bruna Paulsen

Nat Neurosci· November 2022

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Age-linked suppression of lipoxin A4 associates with cognitive deficits in mice and humans.
Fabricio A Pamplona, Gabriela Vitória, Felipe K Sudo, Felipe C Ribeiro, Alinny R Isaac, Bruna Paulsen

Transl Psychiatry· October 2022

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Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex.
Ana Uzquiano, Amanda J Kedaigle, Martina Pigoni, Bruna Paulsen, Xian Adiconis

Cell· September 2022

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Autism genes converge on asynchronous development of shared neuron classes.
Bruna Paulsen, Silvia Velasco, Amanda J Kedaigle, Martina Pigoni, Giorgia Quadrato

Nature· February 2022

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3D Brain Organoids: Studying Brain Development and Disease Outside the Embryo.
Silvia Velasco, Bruna Paulsen, Paola Arlotta

Annu Rev Neurosci· July 2020

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Individual brain organoids reproducibly form cell diversity of the human cerebral cortex.
Silvia Velasco, Amanda J Kedaigle, Sean K Simmons, Allison Nash, Marina Rocha, Bruna Paulsen

Nature· June 2019

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Generation of iPSC-Derived Human Peripheral Sensory Neurons Releasing Substance P Elicited by TRPV1 Agonists.
Marília Z P Guimarães, Rodrigo De Vecchi, Gabriela Vitória, Jaroslaw K Sochacki, Bruna S Paulsen

Front Mol Neurosci· August 2018

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Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing.
Bruna S Paulsen, Pankaj K Mandal, Richard L Frock, Baris Boyraz, Rachita Yadav

Nat Biomed Eng· November 2017

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Co-expression network of neural-differentiation genes shows specific pattern in schizophrenia.
Mariana Maschietto, Ana C Tahira, Renato Puga, Leandro Lima, Daniel Mariani, Bruna da Silveira Paulsen

BMC Med Genomics· May 2015

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Accelerating neuronal aging in in vitro model brain disorders: a focus on reactive oxygen species.
Priscila Britto Campos, Bruna S Paulsen, Stevens K Rehen

Front Aging Neurosci· November 2014

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Valproate reverts zinc and potassium imbalance in schizophrenia-derived reprogrammed cells.
Bruna da Silveira Paulsen, Simone Coutinho Cardoso, Mariana Paranhos Stelling, Daniel Veloso Cadilhe, Stevens Kastrup Rehen

Schizophr Res· April 2014

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Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient.
Bruna da Silveira Paulsen, Renata de Moraes Maciel, Antonio Galina, Mariana Souza da Silveira, Cleide dos Santos Souza

Cell Transplant· August 2013

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Pluripotent stem cells as a model to study oxygen metabolism in neurogenesis and neurodevelopmental disorders.
Bruna da Silveira Paulsen, Mariana Souza da Silveira, Antonio Galina, Stevens Kastrup Rehen

Arch Biochem Biophys· June 2013

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Xeno-free production of human embryonic stem cells in stirred microcarrier systems using a novel animal/human-component-free medium.
Paulo André Nobrega Marinho, Daniel Tait Vareschini, Ismael Carlos Gomes, Bruna da Silveira Paulsen, Daniel Rodrigues Furtado

Tissue Eng Part C Methods· February 2013

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Implications of aneuploidy for stem cell biology and brain therapeutics.
Sylvie Devalle, Rafaela C Sartore, Bruna S Paulsen, Helena L Borges, Rodrigo A P Martins

Front Cell Neurosci· October 2012

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Synchrotron radiation X-ray microfluorescence reveals polarized distribution of atomic elements during differentiation of pluripotent stem cells.
Simone C Cardoso, Mariana P Stelling, Bruna S Paulsen, Stevens K Rehen

PLoS One· August 2012

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Dynamic expression of synemin isoforms in mouse embryonic stem cells and neural derivatives.
Sheila C de Souza Martins, Onnik Agbulut, Nicolas Diguet, Jean-Christophe Larcher, Bruna S Paulsen

BMC Cell Biol· November 2011

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Agathisflavone enhances retinoic acid-induced neurogenesis and its receptors α and β in pluripotent stem cells.
Bruna S Paulsen, Cleide S Souza, Leonardo Chicaybam, Martin Hernán Bonamino, Marcus Bahia

Stem Cells Dev· October 2011

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Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation.
Rafaela C Sartore, Priscila B Campos, Cleber A Trujillo, Bia L Ramalho, Priscilla D Negraes, Bruna S Paulsen

PLoS One· September 2011

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