Publications by authors named "Brunella Brunelli"

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Human monoclonal antibodies targeting subdominant meningococcal antigens confer cross-protection against gonococcus.
Marco Troisi, Monica Fabbrini, Samuele Stazzoni, Viola Viviani, Filippo Carboni, Brunella Brunelli

Sci Transl Med· May 2025

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Testing a Recombinant Form of Tetanus Toxoid as a Carrier Protein for Glycoconjugate Vaccines.
Davide Oldrini, Roberta Di Benedetto, Martina Carducci, Daniele De Simone, Luisa Massai, Brunella Brunelli

Vaccines (Basel)· November 2023

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Enhanced Systemic Humoral Immune Response Induced in Mice by Generalized Modules for Membrane Antigens (GMMA) Is Associated with Affinity Maturation and Isotype Switching.
Diego Piccioli, Francesca Buricchi, Marta Bacconi, Nicoletta Bechi, Barbara Galli, Brunella Brunelli

Vaccines (Basel)· July 2023

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Investigating the Role of Antigen Orientation on the Immune Response Elicited by Factor H Binding Protein on GMMA.
Renzo Alfini, Brunella Brunelli, Erika Bartolini, Martina Carducci, Enrico Luzzi

Vaccines (Basel)· July 2022

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Generalized Modules for Membrane Antigens as Carrier for Polysaccharides: Impact of Sugar Length, Density, and Attachment Site on the Immune Response Elicited in Animal Models.
Francesca Micoli, Renzo Alfini, Roberta Di Benedetto, Francesca Necchi, Fabiola Schiavo, Brunella Brunelli

Front Immunol· December 2021

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4CMenB Immunization Induces Serum Bactericidal Antibodies Against Non-Serogroup B Meningococcal Strains in Adolescents.
Alessia Biolchi, Sara Tomei, Brunella Brunelli, Maria Giuliani, Stefania Bambini

Infect Dis Ther· March 2021

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Multicomponent meningococcal serogroup B vaccination elicits cross-reactive immunity in infants against genetically diverse serogroup C, W and Y invasive disease isolates.
Alessia Biolchi, Gabriella De Angelis, Monica Moschioni, Sara Tomei, Brunella Brunelli

Vaccine· November 2020

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GMMA Is a Versatile Platform to Design Effective Multivalent Combination Vaccines.
Francesca Micoli, Renzo Alfini, Roberta Di Benedetto, Francesca Necchi, Fabiola Schiavo, Brunella Brunelli

Vaccines (Basel)· September 2020

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Synergic complement-mediated bactericidal activity of monoclonal antibodies with distinct specificity.
Eriberto Noel Natali, Silvia Principato, Francesca Ferlicca, Federica Bianchi, Lucia Eleonora Fontana, Brunella Brunelli

FASEB J· August 2020

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Adsorption onto aluminum hydroxide adjuvant protects antigens from degradation.
Annalisa Colaprico, Silvia Senesi, Francesca Ferlicca, Brunella Brunelli, Mildred Ugozzoli

Vaccine· April 2020

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Meningococcal Antigen Typing System (MATS): A Tool to Estimate Global Coverage for 4CMenB, a Multicomponent Meningococcal B Vaccine.
Giuseppe Boccadifuoco, Brunella Brunelli, Elena Mori, Mauro Agnusdei, Claudia Gianfaldoni

Methods Mol Biol· September 2019

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Phage display revisited: Epitope mapping of a monoclonal antibody directed against Neisseria meningitidis adhesin A using the PROFILER technology.
Veronica Lanza Cariccio, Maria Domina, Salvatore Benfatto, Mario Venza, Isabella Venza, Brunella Brunelli

MAbs· November 2017

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Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy.
Enrico Malito, Paola Lo Surdo, Daniele Veggi, Laura Santini, Heather Stefek, Brunella Brunelli

Biochem J· December 2016

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Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined.
Massimiliano Biagini, Marco Spinsanti, Gabriella De Angelis, Sara Tomei, Ilaria Ferlenghi, Brunella Brunelli

Proc Natl Acad Sci U S A· March 2016

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Molecular Engineering of Ghfp, the Gonococcal Orthologue of Neisseria meningitidis Factor H Binding Protein.
Valentina Rippa, Laura Santini, Paola Lo Surdo, Francesca Cantini, Daniele Veggi, Brunella Brunelli

Clin Vaccine Immunol· July 2015

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Outbreaks of meningococcal B infection and the 4CMenB vaccine: historical and future perspectives.
Jane Whelan, Stefania Bambini, Alessia Biolchi, Brunella Brunelli, Mirna Robert-Du Ry van Beest Holle

Expert Rev Vaccines· May 2015

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Rational design of small molecules as vaccine adjuvants.
Tom Y-H Wu, Manmohan Singh, Andrew T Miller, Ennio De Gregorio, Francesco Doro, Brunella Brunelli

Sci Transl Med· November 2014

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Molecular and serological diversity of Neisseria meningitidis carrier strains isolated from Italian students aged 14 to 22 years.
Roberto Gasparini, Maurizio Comanducci, Daniela Amicizia, Filippo Ansaldi, Paola Canepa, Brunella Brunelli

J Clin Microbiol· June 2014

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Transcriptional regulation of the nadA gene in Neisseria meningitidis impacts the prediction of coverage of a multicomponent meningococcal serogroup B vaccine.
Luca Fagnocchi, Alessia Biolchi, Francesca Ferlicca, Giuseppe Boccadifuoco, Brunella Brunelli

Infect Immun· February 2013

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Could the multicomponent meningococcal serogroup B vaccine (4CMenB) control Neisseria meningitidis capsular group X outbreaks in Africa?
Eva Hong, Marzia Monica Giuliani, Ala-Eddine Deghmane, Maurizio Comanducci, Brunella Brunelli

Vaccine· February 2013

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Interlaboratory standardization of the sandwich enzyme-linked immunosorbent assay designed for MATS, a rapid, reproducible method for estimating the strain coverage of investigational vaccines.
Brian D Plikaytis, Maria Stella, Giuseppe Boccadifuoco, Lisa M DeTora, Mauro Agnusdei, Brunella Brunelli

Clin Vaccine Immunol· October 2012

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Antigen identification starting from the genome: a "Reverse Vaccinology" approach applied to MenB.
Emmanuelle Palumbo, Luigi Fiaschi, Brunella Brunelli, Sara Marchi, Silvana Savino

Methods Mol Biol· February 2012

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A naturally occurring single-residue mutation in the translocator domain of Neisseria meningitidis NhhA affects trimerization, surface localization, and adhesive capabilities.
Hebert Echenique-Rivera, Brunella Brunelli, Maria Scarselli, Anna Rita Taddei, Mariagrazia Pizza

Infect Immun· November 2011

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Rational design of a meningococcal antigen inducing broad protective immunity.
Maria Scarselli, Beatrice Aricò, Brunella Brunelli, Silvana Savino, Federica Di Marcello

Sci Transl Med· July 2011

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Characterization of diverse subvariants of the meningococcal factor H (fH) binding protein for their ability to bind fH, to mediate serum resistance, and to induce bactericidal antibodies.
Kate L Seib, Brunella Brunelli, Barbara Brogioni, Emmanuelle Palumbo, Stefania Bambini

Infect Immun· February 2011

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