Publications by authors named "Bruno Calabretta"

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Preclinical evaluation of anti-CD38 therapy in mature T-cell neoplasms.
Colleen Isabelle, William T Johnson, Kathleen McConnell, Ashley Vogel, Jonathan E Brammer, Bruno Calabretta

Blood Adv· July 2023

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A phase I study of the combination of palbociclib and dexamethasone for the treatment of relapsed or refractory B-cell acute lymphoblastic leukemia.
Lindsay Wilde, Patrizia Porazzi, Rossana Trotta, Marco De Dominici, Neil Palmisiano, Bruno Calabretta

Leuk Res· June 2023

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Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression.
Patrizia Porazzi, Svetlana Petruk, Luca Pagliaroli, Marco De Dominici, David Deming, Bruno Calabretta

Cancer Res· February 2022

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Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders.
Luca Pagliaroli, Patrizia Porazzi, Alyxandra T Curtis, Chiara Scopa, Harald M M Mikkers, Bruno Calabretta

Nat Commun· November 2021

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Targeting the CDK6 Dependence of Ph+ Acute Lymphoblastic Leukemia.
Patrizia Porazzi, Marco De Dominici, Joseph Salvino, Bruno Calabretta

Genes (Basel)· August 2021

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Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on Antiproliferative and PP2A-Activating Functions.
Giovannino Silvestri, Rossana Trotta, Lorenzo Stramucci, Justin J Ellis, Jason G Harb, Bruno Calabretta

Blood Cancer Discov· July 2020

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Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs.
Marco De Dominici, Patrizia Porazzi, Youcai Xiao, Allen Chao, Hsin-Yao Tang, Bruno Calabretta

Blood· April 2020

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Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells.
Manuela Spagnuolo, Giulia Regazzo, Marco De Dominici, Andrea Sacconi, Andrea Pelosi, Bruno Calabretta

Haematologica· January 2019

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Targeting the STAT5 pathway in Ph+ acute lymphoblastic leukemia.
Valentina Minieri, Marco De Dominici, Marja T Nevalainen, Bruno Calabretta

Oncotarget· December 2018

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Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb.
Simona D'Aguanno, Elisabetta Valentini, Maria Grazia Tupone, Marianna Desideri, Marta Di Martile, Bruno Calabretta

J Exp Clin Cancer Res· November 2018

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Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia.
Valentina Minieri, Marco De Dominici, Patrizia Porazzi, Samanta A Mariani, Orietta Spinelli, Bruno Calabretta

Cancer Res· October 2018

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KLF4 Mediates the Effect of 5-ASA on the β-Catenin Pathway in Colon Cancer Cells.
Sandra Parenti, Lucia Montorsi, Sebastian Fantini, Fabiana Mammoli, Claudia Gemelli, Bruno Calabretta

Cancer Prev Res (Phila)· August 2018

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Targeted Enhancer Activation by a Subunit of the Integrator Complex.
Elisa Barbieri, Marco Trizzino, Sarah Ann Welsh, Tori Alexandra Owens, Bruno Calabretta

Mol Cell· July 2018

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Targeting BCR-ABL-Independent TKI Resistance in Chronic Myeloid Leukemia by mTOR and Autophagy Inhibition.
Rebecca Mitchell, Lisa E M Hopcroft, Pablo Baquero, Elaine K Allan, Kay Hewit, Bruno Calabretta

J Natl Cancer Inst· May 2018

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Targeting CDK6 and BCL2 Exploits the "MYB Addiction" of Ph Acute Lymphoblastic Leukemia.
Marco De Dominici, Patrizia Porazzi, Angela Rachele Soliera, Samanta A Mariani, Sankar Addya, Bruno Calabretta

Cancer Res· February 2018

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Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification.
Svetlana Petruk, Samanta A Mariani, Marco De Dominici, Patrizia Porazzi, Valentina Minieri, Bruno Calabretta

Cell Rep· April 2017

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Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation.
Svetlana Petruk, Jingli Cai, Robyn Sussman, Guizhi Sun, Sina K Kovermann, Bruno Calabretta

Mol Cell· April 2017

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Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2.
Beatrice Riva, Marco De Dominici, Ilaria Gnemmi, Samanta A Mariani, Alberto Minassi, Bruno Calabretta

Oncotarget· December 2016

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ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells.
Maria Karvela, Pablo Baquero, Elodie M Kuntz, Arunima Mukhopadhyay, Rebecca Mitchell, Bruno Calabretta

Autophagy· June 2016

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Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the Connectivity Map database.
Gloria Manzotti, Sandra Parenti, Giovanna Ferrari-Amorotti, Angela Rachele Soliera, Sara Cattelani, Bruno Calabretta

Cell Cycle· May 2016

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Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.
Zhiyong Liao, Lei Gu, Jenny Vergalli, Samanta A Mariani, Marco De Dominici, Bruno Calabretta

Mol Cancer Ther· August 2015

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Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity.
Giovanna Ferrari-Amorotti, Claudia Chiodoni, Fei Shen, Sara Cattelani, Angela Rachele Soliera, Bruno Calabretta

Neoplasia· December 2014

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Leukemia stem cells: Old concepts and new perspectives.
Samanta A Mariani, Bruno Calabretta

Mol Aspects Med· October 2014

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Autophagy in chronic myeloid leukaemia: stem cell survival and implication in therapy.
Gudmundur V Helgason, Arunima Mukhopadhyay, Maria Karvela, Paolo Salomoni, Bruno Calabretta

Curr Cancer Drug Targets· September 2013

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Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion.
Giovanna Ferrari-Amorotti, Valentina Fragliasso, Roza Esteki, Zelia Prudente, Angela Rachele Soliera, Bruno Calabretta

Cancer Res· January 2013

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