Publications by authors named "Bruno Lefebvre"

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Phospho-Tau Signature During Mitosis: AT8, p-T217 and p-S422 as Key Phospho-Epitopes.
Marion Goussard, Kelly Zarka, Morgane Denus, Thomas Curel, Sylvie Claeysen, Bruno Lefebvre

Cells· October 2025

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Whole-genome sequencing revealed a novel structural variant in causing autosomal dominant Alport syndrome: A case report.
Clément Delage, Marine Andreani, Nihad Boukrout, Naoual Sabaouni, Michaël Perrais, Bruno Lefebvre

Heliyon· December 2024

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MUC1 Drives the Progression and Chemoresistance of Clear Cell Renal Carcinomas.
Emma Bourdon, Thomas Swierczewski, Marine Goujon, Nihad Boukrout, Sandy Fellah, Bruno Lefebvre

Cancers (Basel)· January 2024

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Tau promotes oxidative stress-associated cycling neurons in S phase as a pro-survival mechanism: Possible implication for Alzheimer's disease.
Marine Denechaud, Sarah Geurs, Thomas Comptdaer, Séverine Bégard, Alejandro Garcia-Núñez, Bruno Lefebvre

Prog Neurobiol· April 2023

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Cancer Cells Upregulate Tau to Gain Resistance to DNA Damaging Agents.
Thomas Rico, Marine Denechaud, Raphaelle Caillierez, Thomas Comptdaer, Eric Adriaenssens, Bruno Lefebvre

Cancers (Basel)· December 2022

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Tau Stabilizes Chromatin Compaction.
Thomas Rico, Melissa Gilles, Alban Chauderlier, Thomas Comptdaer, Romain Magnez, Bruno Lefebvre

Front Cell Dev Biol· October 2021

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Emerging Connections Between Tau and Nucleic Acids.
Marie-Christine Galas, Eliette Bonnefoy, Luc Buee, Bruno Lefebvre

Adv Exp Med Biol· April 2020

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Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy.
Jin Zheng, Mansour Akbari, Claire Schirmer, Marie-Line Reynaert, Anne Loyens, Bruno Lefebvre

Acta Neuropathol Commun· March 2020

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Genome-wide identification of genic and intergenic neuronal DNA regions bound by Tau protein under physiological and stress conditions.
Houda Benhelli-Mokrani, Zeyni Mansuroglu, Alban Chauderlier, Benoit Albaud, David Gentien, Bruno Lefebvre

Nucleic Acids Res· November 2018

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Tau/DDX6 interaction increases microRNA activity.
Alban Chauderlier, Melissa Gilles, Andrea Spolcova, Raphaelle Caillierez, Maggy Chwastyniak, Bruno Lefebvre

Biochim Biophys Acta Gene Regul Mech· August 2018

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Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin.
Zeyni Mansuroglu, Houda Benhelli-Mokrani, Vasco Marcato, Audrey Sultan, Marie Violet, Bruno Lefebvre

Sci Rep· September 2016

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Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo.
Marie Violet, Alban Chauderlier, Lucie Delattre, Meryem Tardivel, Meliza Sendid Chouala, Bruno Lefebvre

Neurobiol Dis· October 2015

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Regulation of human MAPT gene expression.
Marie-Laure Caillet-Boudin, Luc Buée, Nicolas Sergeant, Bruno Lefebvre

Mol Neurodegener· July 2015

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When the skeleton is controlling pancreatic β-cell mass during development and after.
Thomas Bouckenooghe, Bruno Lefebvre

Diabetes· March 2014

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A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions.
Marie Violet, Lucie Delattre, Meryem Tardivel, Audrey Sultan, Alban Chauderlier, Bruno Lefebvre

Front Cell Neurosci· March 2014

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mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
Olivier Le Bacquer, Gurvan Queniat, Valery Gmyr, Julie Kerr-Conte, Bruno Lefebvre

J Endocrinol· January 2013

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Regulation and functional effects of ZNT8 in human pancreatic islets.
Bruno Lefebvre, Brigitte Vandewalle, Anne-Sophie Balavoine, Gurvan Queniat, Ericka Moerman

J Endocrinol· August 2012

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Evidence for epithelial-mesenchymal transition in adult human pancreatic exocrine cells.
Marjorie Fanjul, Valéry Gmyr, Coralie Sengenès, Ginette Ratovo, Marlène Dufresne, Bruno Lefebvre

J Histochem Cytochem· September 2010

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Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans.
Bruno Lefebvre, Yacir Benomar, Aurore Guédin, Audrey Langlois, Nathalie Hennuyer, Philippe Lefebvre

J Clin Invest· May 2010

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Efficient gene delivery and silencing of mouse and human pancreatic islets.
Bruno Lefebvre, Brigitte Vandewalle, Justine Longue, Ericka Moerman, Bruno Lukowiak

BMC Biotechnol· March 2010

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5'-AZA induces Ngn3 expression and endocrine differentiation in the PANC-1 human ductal cell line.
Bruno Lefebvre, Sandrine Belaich, Justine Longue, Brigitte Vandewalle, Jose Oberholzer

Biochem Biophys Res Commun· January 2010

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Induction of CXCR2 receptor by peroxisome proliferator-activated receptor gamma in human macrophages.
Elena Rigamonti, Coralie Fontaine, Bruno Lefebvre, Christian Duhem, Philippe Lefebvre

Arterioscler Thromb Vasc Biol· May 2008

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PPARgamma-dependent and -independent effects of rosiglitazone on lipotoxic human pancreatic islets.
Brigitte Vandewalle, Ericka Moerman, Bruno Lefebvre, Frédérique Defrance, Valéry Gmyr

Biochem Biophys Res Commun· February 2008

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S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects.
Maria Carmen Carmona, Katie Louche, Bruno Lefebvre, Antoine Pilon, Nathalie Hennuyer, Philippe Lefebvre

Diabetes· November 2007

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The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor.
Sébastien Flajollet, Bruno Lefebvre, Céline Cudejko, Bart Staels, Philippe Lefebvre

Mol Cell Endocrinol· May 2007

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