Publications by authors named "Bruno Tasso"

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Structure-guided combination of novel CFTR correctors to improve the function of F508del-CFTR in airway epithelial cells.
Dario Lunaccio, Caterina Allegretta, Emanuela Pesce, Naomi Scarano, Virginia Vinci, Bruno Tasso

Biochem Pharmacol· October 2025

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Targeting the p53/xCT/GSH Axis with PRIMA-1 Combined with Sulfasalazine Shows Therapeutic Potential in Chronic Lymphocytic Leukemia.
Martina Pasino, Andrea Speciale, Silvia Ravera, Giovanna Cutrona, Rosanna Massara, Bruno Tasso

Int J Mol Sci· June 2025

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Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays.
Francesco Piacente, Giorgia Guccione, Naomi Scarano, Dario Lunaccio, Caterina Miro, Bruno Tasso

Int J Mol Sci· October 2024

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Investigations of Antioxidant and Anti-Cancer Activities of 5-Aminopyrazole Derivatives.
Federica Rapetti, Andrea Spallarossa, Eleonora Russo, Debora Caviglia, Carla Villa, Bruno Tasso

Molecules· May 2024

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New Pyrazolyl Thioureas Active against the Genus.
Anna Maria Schito, Debora Caviglia, Susanna Penco, Andrea Spallarossa, Elena Cichero, Bruno Tasso

Pharmaceuticals (Basel)· March 2024

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PTC596-Induced BMI-1 Inhibition Fights Neuroblastoma Multidrug Resistance by Inducing Ferroptosis.
Giulia Elda Valenti, Antonella Roveri, Rina Venerando, Paola Menichini, Paola Monti, Bruno Tasso

Antioxidants (Basel)· December 2023

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Further Quinolizidine Derivatives as Antiarrhythmic Agents- 3.
Bruno Tasso, Laura Beatrice Mattioli, Michele Tonelli, Vito Boido, Alberto Chiarini

Molecules· October 2023

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Indole Antitumor Agents in Nanotechnology Formulations: An Overview.
Eleonora Russo, Carola Grondona, Chiara Brullo, Andrea Spallarossa, Carla Villa, Bruno Tasso

Pharmaceutics· June 2023

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New Class of Benzodiazepinone Derivatives as Pro-Death Agents Targeting BIR Domains in Cancer Cells.
Michele Fiore, Michele Mosconi, Francesco Bonì, Alice Parodi, Annalisa Salis, Bruno Tasso

Molecules· January 2023

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Nanotechnology for Pediatric Retinoblastoma Therapy.
Eleonora Russo, Andrea Spallarossa, Bruno Tasso, Carla Villa, Chiara Brullo

Pharmaceuticals (Basel)· August 2022

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Microbiological Screening of 5-Functionalized Pyrazoles for the Future Development of Optimized Pyrazole-Based Delivery Systems.
Chiara Brullo, Debora Caviglia, Andrea Spallarossa, Silvana Alfei, Scott G Franzblau, Bruno Tasso

Pharmaceutics· August 2022

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The Development of FAK Inhibitors: A Five-Year Update.
Andrea Spallarossa, Bruno Tasso, Eleonora Russo, Carla Villa, Chiara Brullo

Int J Mol Sci· June 2022

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Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays.
Alice Parodi, Giada Righetti, Emanuela Pesce, Annalisa Salis, Valeria Tomati, Bruno Tasso

Pharmaceuticals (Basel)· February 2022

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The Development of BTK Inhibitors: A Five-Year Update.
Bruno Tasso, Andrea Spallarossa, Eleonora Russo, Chiara Brullo

Molecules· December 2021

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Synthesis and Structure-activity Relationship of Aminoarylthiazole Derivatives as Potential Potentiators of the Chloride Transport Defect in Cystic Fibrosis.
Nara Liessi, Emanuela Pesce, Annalisa Salis, Gianluca Damonte, Bruno Tasso

Med Chem· August 2021

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Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective.
Chiara Brullo, Carla Villa, Bruno Tasso, Eleonora Russo, Andrea Spallarossa

Int J Mol Sci· July 2021

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New Insights on Fak and Fak Inhibitors.
Chiara Brullo, Bruno Tasso

Curr Med Chem· June 2021

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Nanotechnology of Tyrosine Kinase Inhibitors in Cancer Therapy: A Perspective.
Eleonora Russo, Andrea Spallarossa, Bruno Tasso, Carla Villa, Chiara Brullo

Int J Mol Sci· June 2021

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Multitarget Biological Profiling of New Naphthoquinone and Anthraquinone-Based Derivatives for the Treatment of Alzheimer's Disease.
Marta Campora, Claudio Canale, Elena Gatta, Bruno Tasso, Erik Laurini

ACS Chem Neurosci· February 2021

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Journey on Naphthoquinone and Anthraquinone Derivatives: New Insights in Alzheimer's Disease.
Marta Campora, Valeria Francesconi, Silvia Schenone, Bruno Tasso, Michele Tonelli

Pharmaceuticals (Basel)· January 2021

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Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays.
Alice Parodi, Giada Righetti, Emanuela Pesce, Annalisa Salis, Bruno Tasso

Eur J Med Chem· December 2020

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Quinolizidine-Derived Lucanthone and Amitriptyline Analogues Endowed with Potent Antileishmanial Activity.
Michele Tonelli, Anna Sparatore, Nicoletta Basilico, Loredana Cavicchini, Silvia Parapini, Bruno Tasso

Pharmaceuticals (Basel)· October 2020

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Molecular Docking and QSAR Studies as Computational Tools Exploring the Rescue Ability of F508del CFTR Correctors.
Giada Righetti, Monica Casale, Nara Liessi, Bruno Tasso, Annalisa Salis

Int J Mol Sci· October 2020

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Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules.
Giovanna Sociali, Nara Liessi, Alessia Grozio, Irene Caffa, Marco Daniele Parenti, Bruno Tasso

Mol Divers· August 2020

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Exploring the effectiveness of novel benzimidazoles as CB2 ligands: synthesis, biological evaluation, molecular docking studies and ADMET prediction.
Michele Tonelli, Elena Cichero, Alì Mokhtar Mahmoud, Alessandro Rabbito, Bruno Tasso

Medchemcomm· December 2018

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