Publications by authors named "Bryan Burkey"

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MetAP2 inhibition reduces food intake and body weight in a ciliopathy mouse model of obesity.
Tana S Pottorf, Micaella P Fagan, Bryan F Burkey, David J Cho, James E Vath

JCI Insight· January 2020

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Preclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061.
Bryan F Burkey, Niel C Hoglen, Philip Inskeep, Margaret Wyman, Thomas E Hughes

J Pharmacol Exp Ther· May 2018

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GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice.
Dan Kawamori, Jun Shirakawa, Chong Wee Liew, Jiang Hu, Tomoaki Morioka, Bryan Burkey

Diabetologia· August 2017

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Vascular origin of vildagliptin-induced skin effects in Cynomolgus monkeys: pathomechanistic role of peripheral sympathetic system and neuropeptide Y.
Peter Hoffmann, Phil Bentley, Pritam Sahota, Heidi Schoenfeld, Lori Martin, Bryan Burkey

Toxicol Pathol· June 2014

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Pathways regulated by glucocorticoids in omental and subcutaneous human adipose tissues: a microarray study.
Mi-Jeong Lee, Da-Wei Gong, Bryan F Burkey, Susan K Fried

Am J Physiol Endocrinol Metab· March 2011

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The DPP-4 inhibitor vildagliptin increases pancreatic beta cell mass in neonatal rats.
Alokesh Duttaroy, Frank Voelker, Kimberley Merriam, Xia Zhang, Xianglin Ren, Bryan F Burkey

Eur J Pharmacol· January 2011

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Cevoglitazar, a novel peroxisome proliferator-activated receptor-alpha/gamma dual agonist, potently reduces food intake and body weight in obese mice and cynomolgus monkeys.
Hong Chen, Beatriz Dardik, Ling Qiu, Xianglin Ren, Shari L Caplan, Bryan Burkey

Endocrinology· July 2010

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DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide.
Bo Ahrén, Maria Sörhede Winzell, Nils Wierup, Frank Sundler, Bryan Burkey

Regul Pept· October 2007

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Independent association of insulin resistance with larger amounts of intermuscular adipose tissue and a greater acute insulin response to glucose in African American than in white nondiabetic women.
Jeanine B Albu, Albert J Kovera, Lynn Allen, Marsha Wainwright, Evan Berk, Bryan Burkey

Am J Clin Nutr· December 2005

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Beta-cell expression of a dominant-negative HNF-1alpha compromises the ability of inhibition of dipeptidyl peptidase-4 to elicit a long-term augmentation of insulin secretion in mice.
Bo Ahrén, Maria Sörhede Winzell, Bryan Burkey, Thomas E Hughes

Eur J Pharmacol· October 2005

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1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.
Edwin B Villhauer, John A Brinkman, Goli B Naderi, Bryan F Burkey, Beth E Dunning

J Med Chem· June 2003

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