Publications by authors named "Bryan Copple"

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Good Cells Go Bad: Immune Dysregulation in the Transition from Acute Liver Injury to Liver Failure After Acetaminophen Overdose.
James P Luyendyk, Elena Morozova, Bryan L Copple

Drug Metab Dispos· July 2024

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Interleukin-10 disrupts liver repair in acetaminophen-induced acute liver failure.
Katherine Roth, Jenna Strickland, Asmita Pant, Robert Freeborn, Rebekah Kennedy, Bryan L Copple

Front Immunol· December 2023

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Modulation of macrophage phenotype to treat liver fibrosis-Current approaches and future possibilities.
Jenna D Strickland, Bryan L Copple

Adv Pharmacol· October 2021

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Preface.
Bryan L Copple, Cheryl E Rockwell

Adv Pharmacol· January 2021

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Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer.
Anna Zagórska, Paqui G Través, Lidia Jiménez-García, Jenna D Strickland, Joanne Oh, Bryan L Copple

Life Sci Alliance· August 2020

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Liver fibrosis is driven by protease-activated receptor-1 expressed by hepatic stellate cells in experimental chronic liver injury.
Lauren G Poole, Asmita Pant, Holly M Cline-Fedewa, Kurt J Williams, Bryan L Copple

Res Pract Thromb Haemost· July 2020

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Regulation of macrophage activation in the liver after acute injury: Role of the fibrinolytic system.
Katherine Roth, Jenna Strickland, Bryan L Copple

World J Gastroenterol· April 2020

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Hypoxia upregulates Cxcl12 in hepatocytes by a complex mechanism involving hypoxia-inducible factors and transforming growth factor-β.
Jenna Strickland, Domonique Garrison, Bryan L Copple

Cytokine· March 2020

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Dichotomous Role of Plasmin in Regulation of Macrophage Function after Acetaminophen Overdose.
Katherine Roth, Jenna Strickland, Nikita Joshi, Meihong Deng, Rebekah C Kennedy, Bryan L Copple

Am J Pathol· October 2019

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Differential Sensitivity of Kupffer Cells and Hepatic Monocyte-Derived Macrophages to Bacterial Lipopolysaccharide.
Katherine Roth, Cheryl E Rockwell, Bryan L Copple

Clin Exp Gastroenterol Hepatol· September 2019

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Hepatic ZIP8 deficiency is associated with disrupted selenium homeostasis, liver pathology, and tumor formation.
Liu Liu, Xiangrong Geng, Yihong Cai, Bryan Copple, Masafumi Yoshinaga

Am J Physiol Gastrointest Liver Physiol· October 2018

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Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules.
Bryan L Copple, Tiangang Li

Pharmacol Res· February 2016

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Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice.
Hong-Min Ni, Amar Bhakta, Shaogui Wang, Zhenrui Li, Sharon Manley, Bryan Copple

PLoS One· December 2015

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Role of Hypoxia-Inducible Factors in the Development of Liver Fibrosis.
Katherine J Roth, Bryan L Copple

Cell Mol Gastroenterol Hepatol· November 2015

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E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network.
Yuxia Zhang, Ningyi Xu, Jun Xu, Bo Kong, Bryan Copple

Hepatology· September 2014

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Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy.
Hong-Min Ni, Benjamin L Woolbright, Jessica Williams, Bryan Copple, Wei Cui

J Hepatol· September 2014

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Hepatic stellate cells orchestrate clearance of necrotic cells in a hypoxia-inducible factor-1α-dependent manner by modulating macrophage phenotype in mice.
Akie Mochizuki, Aaron Pace, Cheryl E Rockwell, Katherine J Roth, Aaron Chow, Bryan L Copple

J Immunol· April 2014

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Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice.
Min Yang, Anup Ramachandran, Hui-Min Yan, Benjamin L Woolbright, Bryan L Copple

Toxicol Lett· January 2014

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IL-17A synergistically enhances bile acid-induced inflammation during obstructive cholestasis.
Kate M O'Brien, Katryn M Allen, Cheryl E Rockwell, Keara Towery, James P Luyendyk, Bryan L Copple

Am J Pathol· November 2013

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Therapeutic administration of the direct thrombin inhibitor argatroban reduces hepatic inflammation in mice with established fatty liver disease.
Karen M Kassel, Bradley P Sullivan, Wei Cui, Bryan L Copple, James P Luyendyk

Am J Pathol· October 2012

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Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice.
Bryan L Copple, Sophia Kaska, Callie Wentling

J Pharmacol Exp Ther· May 2012

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Aspirin enhances doxorubicin-induced apoptosis and reduces tumor growth in human hepatocellular carcinoma cells in vitro and in vivo.
Mohammad Akbar Hossain, Dong Hwan Kim, Jung Yoon Jang, Yong Jung Kang, Jeong-Hyun Yoon, Bryan L Copple

Int J Oncol· May 2012

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Aspirin induces apoptosis in vitro and inhibits tumor growth of human hepatocellular carcinoma cells in a nude mouse xenograft model.
Mohammad Akbar Hossain, Dong Hwan Kim, Jung Yoon Jang, Yong Jung Kang, Jeong-Hyun Yoon, Bryan L Copple

Int J Oncol· April 2012

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Early growth response factor-1 limits biliary fibrosis in a model of xenobiotic-induced cholestasis in mice.
Bradley P Sullivan, Wei Cui, Bryan L Copple, James P Luyendyk

Toxicol Sci· March 2012

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Effect of bile duct ligation on bile acid composition in mouse serum and liver.
Youcai Zhang, Ji-Young Hong, Cheryl E Rockwell, Bryan L Copple, Hartmut Jaeschke

Liver Int· January 2012

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