Publications by authors named "Bryan Harder"

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The mechanisms underlying the enhanced high-temperature properties of GRX-810.
Timothy M Smith, Christopher A Kantzos, Bryan J Harder, Andreas Bezold, Milan Heczko

Nat Commun· December 2025

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Establishing a consensus definition of VEXAS flare for clinical research.
Lachelle D Weeks, Danielle Hammond, Sinisa Savic, Maël Heiblig, Onima Chowdhury, Bryan G Harder

Rheumatology (Oxford)· November 2025

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Pacritinib is a potent ACVR1 inhibitor with significant anemia benefit in patients with myelofibrosis.
Stephen T Oh, Ruben A Mesa, Claire N Harrison, Prithviraj Bose, Aaron T Gerds, Bryan G Harder

Blood Adv· October 2023

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A 3D printable alloy designed for extreme environments.
Timothy M Smith, Christopher A Kantzos, Nikolai A Zarkevich, Bryan J Harder, Milan Heczko

Nature· May 2023

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Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells.
Bryan G Harder, Sen Peng, Christopher P Sereduk, Andrej M Sodoma, Gaspar J Kitange

Mol Med· November 2019

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Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma.
Bryan G Harder, Mylan R Blomquist, Junwen Wang, Anthony J Kim, Graeme F Woodworth

Front Oncol· October 2018

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The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance.
David S Hersh, Bryan G Harder, Alison Roos, Sen Peng, Jonathan E Heath

Neuro Oncol· September 2018

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Low-level arsenic causes proteotoxic stress and not oxidative stress.
Matthew Dodson, Montserrat Rojo de la Vega, Bryan Harder, Raul Castro-Portuguez, Silvia D Rodrigues

Toxicol Appl Pharmacol· February 2018

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Arsenic Compromises Both p97 and Proteasome Functions.
Joseph Tillotson, Christopher J Zerio, Bryan Harder, Andrew J Ambrose, Kevin S Jung

Chem Res Toxicol· July 2017

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Brusatol overcomes chemoresistance through inhibition of protein translation.
Bryan Harder, Wang Tian, James J La Clair, Aik-Choon Tan, Aikseng Ooi

Mol Carcinog· May 2017

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Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle-age period.
Mandi J Corenblum, Sneha Ray, Quentin W Remley, Min Long, Bryan Harder

Aging Cell· August 2016

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Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy?
Tongde Wu, Bryan G Harder, Pak K Wong, Julie E Lang, Donna D Zhang

Mol Carcinog· November 2015

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p62 links autophagy and Nrf2 signaling.
Tao Jiang, Bryan Harder, Montserrat Rojo de la Vega, Pak K Wong, Eli Chapman

Free Radic Biol Med· November 2015

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Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention.
Bryan Harder, Tao Jiang, Tongde Wu, Shasha Tao, Montserrat Rojo de la Vega

Biochem Soc Trans· August 2015

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Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene.
Mark J Canet, Matthew D Merrell, Bryan G Harder, Jonathan M Maher, Tongde Wu

Drug Metab Dispos· January 2015

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Pharmacological evidence for an abstinence-induced switch in 5-HT1B receptor modulation of cocaine self-administration and cocaine-seeking behavior.
Nathan S Pentkowski, Bryan G Harder, Samuel J Brunwasser, Ryan M Bastle, Natalie A Peartree

ACS Chem Neurosci· March 2014

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Plant extracts of the family Lauraceae: a potential resource for chemopreventive agents that activate the nuclear factor-erythroid 2-related factor 2/antioxidant response element pathway.
Tao Shen, Xue-Mei Chen, Bryan Harder, Min Long, Xiao-Ning Wang

Planta Med· March 2014

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