Publications by authors named "Bryan Hennessy"

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Dose Adjusted Neoadjuvant Paclitaxel, Carboplatin, Trastuzumab and Pertuzumab in Women With HER2 Positive Early Breast Cancer.
Carolyn Moloney-Lineen, Maggie O'Connor, Caroline O'Leary, Paryani Hadia, David Solaligue, Bryan T Hennessy

Clin Breast Cancer· December 2025

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Contrasting roles of KMT2C and KMT2D in breast cancer.
Emily Tinsley, Philip Bredin, Sinead Toomey, Bryan T Hennessy, Simon J Furney

Sci Rep· October 2025

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Operational determinants of recruitment and biospecimen collection in translational observational studies: a multi-site comparative analysis.
Ciarán Devoy, Ronan Andrew McLaughlin, Christopher Cronin, Rachel Clarke, Roisin M Connolly, Bryan T Hennessy

J Transl Med· October 2025

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Implementation of neoadjuvant immunotherapy in stage III melanoma: a modified Delphi consensus study in a European-accredited cancer center in Ireland.
Christopher Cronin, Fiachra Martin, James D Martin-Smith, Nadeem Ajmal, Paul Sullivan, Bryan T Hennessy

Oncologist· September 2025

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Lung Health Check pilot: Ireland's flagship lung cancer screening trial.
David O Reilly, Sandra Roche, Claire Noonan, Jack O'Shea, Sinead Toomey, Bryan T Hennessy

BMJ Open Respir Res· September 2025

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Cutaneous Immune-Related Adverse Events and Efficacy of Immune Checkpoint Inhibitors for Patients With Advanced Solid Organ Malignancies.
David O'Reilly, Gregg Murray, Orla M Fitzpatrick, Hebatalla Ismail, Gavin P Dowling, Bryan T Hennessy

Int J Dermatol· September 2025

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Neoadjuvant chemoradiation in older Irish adult patients with oesophageal cancer: a retrospective institutional review of clinical outcomes and hematological toxicity.
Ronan Andrew McLaughlin, David McMahon, Christopher Cluxton, Orla Meave Fitzpatrick, Michael Conroy, Bryan T Hennessy

BMC Cancer· August 2025

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Clinical benefit and cost of plasma-first next-generation sequencing in patients with newly diagnosed advanced non-small cell lung cancer in Ireland: The PLAN study.
David O'Reilly, Anthony O'Grady, Conor Hayes, Laura Piggott, Ruaidhri Keane, Bryan T Hennessy

Eur J Cancer· July 2025

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Molecular subtyping of endometrial carcinoma cell lines uncovers subtype-specific targetable vulnerabilities.
Eunice S Li, Rebecca Ho, Ran Tao, Yannes Wai Yan Choi, Chae Young Shin, Bryan T Hennessy

NPJ Precis Oncol· July 2025

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Liquid biopsy in lung cancer.
Sile Toland, Padraic Ridge, Emmet O'Brien, Ross Morgan, Sinead Toomey, Bryan T Hennessy

Breathe (Sheff)· July 2025

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TCHL - a phase II neo-adjuvant study assessing TCH (docetaxel, carboplatin and trastuzumab) and TCHL (docetaxel, carboplatin, trastuzumab and lapatinib) in HER-2 positive breast cancer patients: a 5-year follow-up with serum biomarker analysis.
John Crown, Alex J Eustace, Denis M Collins, Maccon Keane, Linda Coate, Bryan T Hennessy

Acta Oncol· June 2025

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Targeting the phosphatidylinositol-3-kinase (PI3K) and mitogen activated protein kinase (MAPK) signalling pathways to enhance chemoradiotherapy in locally advanced rectal cancer.
Aoife Carr, Jonathan A Coulter, Julie Workman, Joanna Fay, Angela Farrelly, Bryan T Hennessy

Cancer Treat Res Commun· May 2025

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Prognostic Significance of Delays in Initiation of Adjuvant Trastuzumab-Based Therapy in Patients with HER2-Positive Breast Cancer.
Gavin P Dowling, Aisling Hegarty, Gordon R Daly, Sandra Hembrecht, Cian M Hehir, Bryan T Hennessy

Biomedicines· May 2025

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A Phase Ia/b study of MEK1/2 inhibitor binimetinib with MET inhibitor crizotinib in patients with RAS mutant advanced colorectal cancer (MErCuRIC).
Francesca Aroldi, Elena Elez, Thierry André, Geraldine Perkins, Hans Prenen, Bryan T Hennessy

BMC Cancer· April 2025

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A phase Ia study of the MEK1/2 inhibitor PD-0325901 with the c-MET inhibitor crizotinib in patients with advanced solid cancers.
Peter Gallagher, Christian Rolfo, Elena Elez, Julien Taieb, Jennifer Houlden, Bryan T Hennessy

BJC Rep· March 2025

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Neoadjuvant HER2 inhibition induces ESR1 DNA methylation alterations resulting in clinically relevant ER expression changes in breast cancers.
Gavin P Dowling, Gordon R Daly, Aisling Hegarty, Michael Flanagan, Mihaela Ola, Bryan Hennessy

Cancer Commun (Lond)· February 2025

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Survival with Trastuzumab Emtansine in Residual HER2-Positive Breast Cancer.
Charles E Geyer, Michael Untch, Chiun-Sheng Huang, Max S Mano, Eleftherios P Mamounas, Bryan T Hennessy

N Engl J Med· January 2025

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Case report: Clonal evolution analysis of a rare case of meningioma lung metastases identifies actionable alterations in matched longitudinal tumour samples.
Nicola Cosgrove, Orla M Fitzpatrick, Liam Grogan, Bryan T Hennessy, Simon J Furney

Front Oncol· January 2025

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Synergistic Effects of the Combination of Alpelisib (PI3K Inhibitor) and Ribociclib (CDK4/6 Inhibitor) in Preclinical Colorectal Cancer Models.
Razia Aslam, Cathy E Richards, Joanna Fay, Lance Hudson, Julie Workman, Bryan T Hennessy

Int J Mol Sci· December 2024

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Neratinib plus dasatinib is highly synergistic in HER2-positive breast cancer in vitro and in vivo.
Neil T Conlon, Sandra Roche, Amira F Mahdi, Alacoque Browne, Laura Breen, Bryan T Hennessy

Transl Oncol· November 2024

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Receptor Discordance in Metastatic Breast Cancer; a review of clinical and genetic subtype alterations from primary to metastatic disease.
Gavin P Dowling, Stephen Keelan, Nicola S Cosgrove, Gordon R Daly, Katie Giblin, Bryan T Hennessy

Breast Cancer Res Treat· October 2024

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Author response to: Comment on: Predictive value of pretreatment circulating inflammatory response markers in the neoadjuvant treatment of breast cancer: meta-analysis.
Gavin P Dowling, Gordon R Daly, Aisling Hegarty, Sandra Hembrecht, Aisling Bracken, Bryan T Hennessy

Br J Surg· July 2024

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Chromosomal copy number and mutational status are required to authenticate ovarian cancer cell lines as appropriate cell models.
Britta Stordal, Angela M Farrelly, Bryan T Hennessy

Mol Biol Rep· June 2024

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Predictive value of pretreatment circulating inflammatory response markers in the neoadjuvant treatment of breast cancer: meta-analysis.
Gavin P Dowling, Gordon R Daly, Aisling Hegarty, Sandra Hembrecht, Aisling Bracken, Bryan T Hennessy

Br J Surg· May 2024

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Genome Sequencing of Multiple Primary Lung Cancers Harbouring Mixed Histology and Spontaneously Regressing Small-Cell Lung Cancer.
Valentina Thomas, Ahmed Rashed, Clare Faul, Siobhan Nicholson, Vincent Young, Bryan T Hennessy

J Pers Med· February 2024

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