Publications by authors named "Bryan Hurtle"

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Context-dependent Interactors Regulate TDP-43 Dysfunction in ALS/FTLD.
Longxin Xie, Yuehua Zhu, Bryan T Hurtle, Matthew Wright, John L Robinson

bioRxiv· April 2025

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Live-cell visualization of tau aggregation in human neurons.
Bryan Hurtle, Christopher J Donnelly, Xin Zhang, Amantha Thathiah

Commun Biol· September 2024

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Ligand-Based Virtual Screening as a Path to New Chemotypes for Candidate PET Radioligands for Imaging Tauopathies.
Bryan T Hurtle, Susovan Jana, Lisheng Cai, Victor W Pike

J Med Chem· August 2024

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CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function.
Longxin Xie, Jessica Merjane, Cristian A Bergmann, Jiazhen Xu, Bryan Hurtle

bioRxiv· July 2024

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Disrupting pathologic phase transitions in neurodegeneration.
Bryan T Hurtle, Longxin Xie, Christopher J Donnelly

J Clin Invest· July 2023

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G protein-biased GPR3 signaling ameliorates amyloid pathology in a preclinical Alzheimer's disease mouse model.
Yunhong Huang, Thais Rafael Guimarães, Nicholas Todd, Carolyn Ferguson, Kathryn M Weiss, Bryan T Hurtle

Proc Natl Acad Sci U S A· October 2022

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RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
Jacob R Mann, Amanda M Gleixner, Jocelyn C Mauna, Edward Gomes, Michael R DeChellis-Marks, Bryan Hurtle

Neuron· April 2019

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Candidate PET Radioligand Development for Neurofibrillary Tangles: Two Distinct Radioligand Binding Sites Identified in Postmortem Alzheimer's Disease Brain.
Lisheng Cai, Baoxi Qu, Bryan T Hurtle, Sureshbabu Dadiboyena, Ramon Diaz-Arrastia

ACS Chem Neurosci· July 2016

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