Publications by authors named "Bryan Killinger"

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Physiological α-synuclein S129 phosphorylation mediates postsynaptic and nuclear interactions in the human brain.
Solji G Choi, Jayda B Duvernay, Atousa Bahrami, Tyler Tittle, Sepehr Sani, Bryan A Killinger

bioRxiv· November 2025

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CD11b Activation Reduces Myeloid Brain Infiltration and Mitigates Synucleinopathy in a Model of Parkinson's Disease.
Ameera M Shaw, Viviana Jimenez, Billy Nguyen, Jayda Duvernay, Solji Choi, Bryan A Killinger

bioRxiv· August 2025

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A Dual-Mode Targeted Nanopore Sequencing Assay for Comprehensive SMN1 and SMN2 Variant Analysis.
Bradley Hall, Sawsan Alyafei, Sathishkumar Ramaswamy, Shruti Sinha, Maha El Naofal, Bryan J Killinger

J Mol Diagn· June 2025

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Proximity proteomics reveals unique and shared pathological features between multiple system atrophy and Parkinson's disease.
Solji G Choi, Tyler R Tittle, Raj R Barot, Dakota J Betts, Johnie J Gallagher, Bryan A Killinger

Acta Neuropathol Commun· March 2025

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Neither alpha-synuclein fibril strain nor host murine genotype influences seeding efficacy.
Sara Walton, Alexis Fenyi, Tyler Tittle, Ellen Sidransky, Gian Pal, Bryan A Killinger

NPJ Parkinsons Dis· May 2024

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Neither alpha-synuclein-preformed fibrils derived from patients with mutations nor the host murine genotype significantly influence seeding efficacy in the mouse olfactory bulb.
Sara Walton, Alexis Fenyi, Tyler Tittle, Ellen Sidransky, Gian Pal, Bryan A Killinger

bioRxiv· August 2023

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Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis.
Bryan A Killinger, Gabriela Mercado, Solji Choi, Tyler Tittle, Yaping Chu

NPJ Parkinsons Dis· March 2023

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Activity-based protein profiling identifies alternating activation of enzymes involved in the bifidobacterium shunt pathway or mucin degradation in the gut microbiome response to soluble dietary fiber.
Bryan J Killinger, Christopher Whidbey, Natalie C Sadler, Adrian J DeLeon, Nathalie Munoz

NPJ Biofilms Microbiomes· July 2022

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Environmental triggers of Parkinson's disease - Implications of the Braak and dual-hit hypotheses.
Honglei Chen, Keran Wang, Filip Scheperjans, Bryan Killinger

Neurobiol Dis· February 2022

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In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain.
Bryan A Killinger, Lee L Marshall, Diptaman Chatterjee, Yaping Chu, Jose Bras

Proc Natl Acad Sci U S A· February 2022

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Epigenetic inactivation of the autophagy-lysosomal system in appendix in Parkinson's disease.
Juozas Gordevicius, Peipei Li, Lee L Marshall, Bryan A Killinger, Sean Lang

Nat Commun· August 2021

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Activity-Based Protein Profiling of Bile Salt Hydrolysis in the Human Gut Microbiome with Beta-Lactam or Acrylamide-Based Probes.
Kristoffer R Brandvold, Carson J Miller, Regan F Volk, Bryan J Killinger, Christopher Whidbey

Chembiochem· April 2021

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Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson's Disease.
Peipei Li, Bryan A Killinger, Elizabeth Ensink, Ian Beddows, Ali Yilmaz

Metabolites· January 2021

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Detecting differential protein abundance by combining peptide level P-values.
Bryan J Killinger, Vladislav A Petyuk, Aaron T Wright

Mol Omics· December 2020

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Epigenomic analysis of Parkinson's disease neurons identifies Tet2 loss as neuroprotective.
Lee L Marshall, Bryan A Killinger, Elizabeth Ensink, Peipei Li, Katie X Li

Nat Neurosci· October 2020

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The Appendix in Parkinson's Disease: From Vestigial Remnant to Vital Organ?
Bryan Killinger, Viviane Labrie

J Parkinsons Dis· July 2020

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Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let's talk about the lipids in the room.
Bryan A Killinger, Ronald Melki, Patrik Brundin, Jeffrey H Kordower

NPJ Parkinsons Dis· November 2019

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Spreading of alpha-synuclein - relevant or epiphenomenon?
Bryan A Killinger, Jeffrey H Kordower

J Neurochem· September 2019

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Benzo[ a]pyrene Induction of Glutathione S-Transferases: An Activity-Based Protein Profiling Investigation.
Ethan G Stoddard, Bryan J Killinger, Subhasree A Nag, Jude Martin, Richard Corley

Chem Res Toxicol· June 2019

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Differential methylation of enhancer at IGF2 is associated with abnormal dopamine synthesis in major psychosis.
Shraddha Pai, Peipei Li, Bryan Killinger, Lee Marshall, Peixin Jia

Nat Commun· May 2019

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The vermiform appendix impacts the risk of developing Parkinson's disease.
Bryan A Killinger, Zachary Madaj, Jacek W Sikora, Nolwen Rey, Alec J Haas

Sci Transl Med· October 2018

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A Cobalamin Activity-Based Probe Enables Microbial Cell Growth and Finds New Cobalamin-Protein Interactions across Domains.
Joshua J Rosnow, Sungmin Hwang, Bryan J Killinger, Young-Mo Kim, Ronald J Moore

Appl Environ Microbiol· September 2018

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Activity-Based Probes for Isoenzyme- and Site-Specific Functional Characterization of Glutathione S-Transferases.
Ethan G Stoddard, Bryan J Killinger, Reji N Nair, Natalie C Sadler, Regan F Volk

J Am Chem Soc· November 2017

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Vertebrate food products as a potential source of prion-like α-synuclein.
Bryan Andrew Killinger, Viviane Labrie

NPJ Parkinsons Dis· November 2017

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Multimer-PAGE: A Method for Capturing and Resolving Protein Complexes in Biological Samples.
Tyler Rhinesmith, Bryan A Killinger, Akhil Sharma, Anna Moszczynska

J Vis Exp· May 2017

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