Publications by authors named "Bryan Mayer"

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Hydrogel formulations for sustained-release of broadly neutralizing antibodies.
Carolyn K Jons, Catherine M Kasse, Bryan T Mayer, Ollivier Hyrien, Samya Sen

J Control Release· December 2025

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Bayesian estimation of HIV acquisition dates for prevention trials.
Raabya Rossenkhan, Elena E Giorgi, Danica Shao, James Ludwig, Phillip Labuschagne, Bryan T Mayer

mBio· October 2025

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VRC01 Selects Rare HIV Escape Mutations After Acquisition in Antibody-Mediated Prevention Trials.
Carolyn Williamson, Lyle Curry, Nonhlanhla N Mkhize, Elena E Giorgi, Craig A Magaret, Bryan T Mayer

bioRxiv· October 2025

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Dose finding in early-phase human immunodeficiency virus type 1 prevention monoclonal antibody clinical trials.
Yunda Huang, Bo Zhang, Lily Zhang, Bryan T Mayer, Troy Martin

Clin Trials· August 2025

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A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV.
Mohammad M Sajadi, Abdolrahim Abbasi, Zahra Rikhtegaran Tehrani, Christine Siska, Rutilio Clark, Bryan T Mayer

Structure· July 2025

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Influence of the broadly neutralizing antibody VRC01 on HIV breakthrough virus populations in antibody-mediated prevention trials.
Carolyn Williamson, Chivonne Moodley, Craig A Magaret, Elena E Giorgi, Morgane Rolland, Bryan Mayer

bioRxiv· July 2025

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Engineering Sustained-Release Broadly Neutralizing Antibody Formulations.
Carolyn K Jons, Catherine M Kasse, Bryan T Mayer, Ollivier Hyrien, Samya Sen

bioRxiv· June 2025

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A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions.
Sedem Dankwa, Christina Kosman, Maria Dennis, Elena E Giorgi, Kenneth Vuong, Bryan T Mayer

PLoS One· November 2024

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A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV.
Mohammad M Sajadi, Abdolrahim Abbasi, Zahra Rikhtegaran Tehrani, Christine Siska, Rutilio Clark, Bryan T Mayer

bioRxiv· October 2024

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Impact of LS Mutation on Pharmacokinetics of Preventive HIV Broadly Neutralizing Monoclonal Antibodies: A Cross-Protocol Analysis of 16 Clinical Trials in People without HIV.
Bryan T Mayer, Lily Zhang, Allan C deCamp, Chenchen Yu, Alicia Sato, Kenneth Mayer

Pharmaceutics· April 2024

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Author Correction: High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials.
Daniel B Reeves, Bryan T Mayer, Allan C deCamp, Yunda Huang, Bo Zhang

Nat Commun· March 2024

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mRNA-Based Vaccines Are Highly Immunogenic and Confer Protection in the Gnotobiotic Pig Model of Human Rotavirus Diarrhea.
Casey Hensley, Sandro Roier, Peng Zhou, Sofia Schnur, Charlotte Nyblade, Bryan T Mayer

Vaccines (Basel)· March 2024

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Establishing RTS,S/AS01 as a benchmark for comparison to next-generation malaria vaccines in a mouse model.
Emily Locke, Yevel Flores-Garcia, Bryan T Mayer, Randall S MacGill, Bhavesh Borate

NPJ Vaccines· February 2024

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High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials.
Daniel B Reeves, Bryan T Mayer, Allan C deCamp, Yunda Huang, Bo Zhang

Nat Commun· December 2023

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Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition.
Peter B Gilbert, Yunda Huang, Allan C deCamp, Shelly Karuna, Yuanyuan Zhang, Bryan T Mayer

Nat Med· September 2022

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Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial.
Boris Julg, Kathryn E Stephenson, Kshitij Wagh, Sabrina C Tan, Rebecca Zash, Bryan T Mayer

Nat Med· June 2022

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Optimizing clinical dosing of combination broadly neutralizing antibodies for HIV prevention.
Bryan T Mayer, Allan C deCamp, Yunda Huang, Joshua T Schiffer, Raphael Gottardo

PLoS Comput Biol· April 2022

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Estimation of the in vivo neutralization potency of eCD4Ig and conditions for AAV-mediated production for SHIV long-term remission.
Ashish Goyal, Matthew Gardner, Bryan T Mayer, Keith R Jerome, Michael Farzan

Sci Adv· January 2022

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Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial.
Kathryn E Stephenson, Boris Julg, C Sabrina Tan, Rebecca Zash, Stephen R Walsh, Bryan Mayer

Nat Med· October 2021

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Slight reduction in SARS-CoV-2 exposure viral load due to masking results in a significant reduction in transmission with widespread implementation.
Ashish Goyal, Daniel B Reeves, Niket Thakkar, Mike Famulare, E Fabián Cardozo-Ojeda, Bryan T Mayer

Sci Rep· June 2021

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Safety and immunogenicity of an HIV-1 gp120-CD4 chimeric subunit vaccine in a phase 1a randomized controlled trial.
Joel V Chua, Charles Davis, Jennifer S Husson, Amy Nelson, Ilia Prado, Bryan T Mayer

Vaccine· June 2021

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Timing HIV infection with a simple and accurate population viral dynamics model.
Daniel B Reeves, Morgane Rolland, Bethany L Dearlove, Yifan Li, Merlin L Robb, Bryan T Mayer

J R Soc Interface· June 2021

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Viral load and contact heterogeneity predict SARS-CoV-2 transmission and super-spreading events.
Ashish Goyal, Daniel B Reeves, E Fabian Cardozo-Ojeda, Joshua T Schiffer, Bryan T Mayer

Elife· February 2021

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Thresholds for post-rebound SHIV control after CCR5 gene-edited autologous hematopoietic cell transplantation.
E Fabian Cardozo-Ojeda, Elizabeth R Duke, Christopher W Peterson, Daniel B Reeves, Bryan T Mayer

Elife· January 2021

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Wrong person, place and time: viral load and contact network structure predict SARS-CoV-2 transmission and super-spreading events.
Ashish Goyal, Daniel B Reeves, E Fabian Cardozo-Ojeda, Joshua T Schiffer, Bryan T Mayer

medRxiv· September 2020

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