Publications by authors named "Bryan Welm"

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Determination of Drug Sensitivity in Patient Derived Models of Breast Cancer by Multiparametric QPI.
Edward R Polanco, Tarek E Moustafa, Ozlen Balcioglu, Sandra D Scherer, Emilio Cortes-Sanchez, Alana L Welm, Bryan E Welm

bioRxiv· October 2025

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Author Correction: Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.
Conan G Kinsey, Soledad A Camolotto, Amelie M Boespflug, Katrin P Guillen, Mona Foth, Alana L Welm, Bryan E Welm

Nat Med· June 2025

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Breast cancer PDxO cultures for drug discovery and functional precision oncology.
Sandra D Scherer, Ling Zhao, Andrew J Butterfield, Chieh-Hsiang Yang, Emilio Cortes-Sanchez, Bryan E Welm, Alana L Welm

STAR Protoc· March 2025

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Patient-Derived Xenografts of Triple-Negative Breast Cancer Enable Deconvolution and Prediction of Chemotherapy Responses.
Jonathan T Lei, Lacey E Dobrolecki, Chen Huang, Ramakrishnan R Srinivasan, Suhas V Vasaikar, Bryan E Welm, Alana L Welm

bioRxiv· January 2025

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A precision oncology-focused deep learning framework for personalized selection of cancer therapy.
Casey Sederman, Chieh-Hsiang Yang, Emilio Cortes-Sanchez, Tony Di Sera, Xiaomeng Huang, Bryan E Welm, Alana L Welm

bioRxiv· December 2024

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Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations.
Funda Meric-Bernstam, Michael W Lloyd, Soner Koc, Yvonne A Evrard, Lisa M McShane, Alana Welm, Bryan Welm

Mol Cancer Ther· July 2024

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TOWARDS Study: Patient-Derived Xenograft Engraftment Predicts Poor Survival in Patients With Newly Diagnosed Triple-Negative Breast Cancer.
Christos Vaklavas, Cindy B Matsen, Zhengtao Chu, Kenneth M Boucher, Sandra D Scherer, Bryan E Welm, Alana L Welm

JCO Precis Oncol· July 2024

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A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis.
Brian S White, Xing Yi Woo, Soner Koc, Todd Sheridan, Steven B Neuhauser, Alana L Welm, Bryan E Welm

Cancer Res· July 2024

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Combining the Tyrosine Kinase Inhibitor Cabozantinib and the mTORC1/2 Inhibitor Sapanisertib Blocks ERK Pathway Activity and Suppresses Tumor Growth in Renal Cell Carcinoma.
Yige Wu, Siqi Chen, Xiaolu Yang, Kazuhito Sato, Preet Lal, Bryan E Welm, Alana L Welm

Cancer Res· December 2023

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Breast cancer PDxO cultures for drug discovery and functional precision oncology.
Sandra D Scherer, Ling Zhao, Andrew J Butterfield, Chieh-Hsiang Yang, Emilio Cortes-Sanchez, Bryan E Welm, Alana L Welm

STAR Protoc· September 2023

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Identifying biomarkers of differential chemotherapy response in TNBC patient-derived xenografts with a CTD/WGCNA approach.
Varduhi Petrosyan, Lacey E Dobrolecki, Lillian Thistlethwaite, Alaina N Lewis, Christina Sallas, Alana L Welm, Bryan E Welm

iScience· January 2023

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A path to translation: How 3D patient tumor avatars enable next generation precision oncology.
Shree Bose, Margarida Barroso, Milan G Chheda, Hans Clevers, Elena Elez, Alana L Welm, Bryan E Welm

Cancer Cell· December 2022

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Immunologically "cold" triple negative breast cancers engraft at a higher rate in patient derived xenografts.
Varduhi Petrosyan, Lacey E Dobrolecki, Emily L LaPlante, Ramakrishnan Rajaram Srinivasan, Matthew H Bailey, Alana L Welm, Bryan E Welm

NPJ Breast Cancer· September 2022

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Multiparametric quantitative phase imaging for real-time, single cell, drug screening in breast cancer.
Edward R Polanco, Tarek E Moustafa, Andrew Butterfield, Sandra D Scherer, Emilio Cortes-Sanchez, Bryan E Welm

Commun Biol· August 2022

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PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery.
Soner Koc, Michael W Lloyd, Jeffrey W Grover, Nan Xiao, Sara Seepo, Alana L Welm, Bryan E Welm

NAR Cancer· June 2022

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A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology.
Katrin P Guillen, Maihi Fujita, Andrew J Butterfield, Sandra D Scherer, Matthew H Bailey, Bryan E Welm, Alana L Welm

Nat Cancer· February 2022

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Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment.
Hua Sun, Song Cao, R Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Alana L Welm, Bryan E Welm

Nat Commun· January 2022

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Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment.
Hua Sun, Song Cao, R Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Alana L Welm, Bryan E Welm

Nat Commun· August 2021

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PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER breast cancer.
Thu H Truong, Elizabeth A Benner, Kyla M Hagen, Nuri A Temiz, Carlos Perez Kerkvliet, Bryan E Welm

Oncogene· June 2021

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Erratum: "Toward improved models of human cancer" [APL Bioeng. , 010901 (2021)].
Bryan E Welm, Christos Vaklavas, Alana L Welm

APL Bioeng· June 2021

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Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
Xing Yi Woo, Jessica Giordano, Anuj Srivastava, Zi-Ming Zhao, Michael W Lloyd, Alana L Welm, Bryan E Welm

Nat Genet· May 2021

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Large-Scale Identification of Clonal Hematopoiesis and Mutations Recurrent in Blood Cancers.
Julie E Feusier, Sasi Arunachalam, Tsewang Tashi, Monika J Baker, Chad VanSant-Webb, Bryan E Welm

Blood Cancer Discov· May 2021

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Toward improved models of human cancer.
Bryan E Welm, Christos Vaklavas, Alana L Welm

APL Bioeng· March 2021

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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
Xing Yi Woo, Jessica Giordano, Anuj Srivastava, Zi-Ming Zhao, Michael W Lloyd, Alana L Welm, Bryan E Welm

Nat Genet· January 2021

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Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate.
Blake R Wilde, Mohan R Kaadige, Katrin P Guillen, Andrew Butterfield, Bryan E Welm

Cancer Metab· December 2020

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