Publications by authors named "Bryan Yip"

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Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model.
Manuel E Lopez, Daniel Wendt, Roger Lawrence, Kerui Gong, Hoonsan Ong, Bryan Yip

PLoS One· January 2025

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Substrate reduction therapy for Krabbe disease and metachromatic leukodystrophy using a novel ceramide galactosyltransferase inhibitor.
Michael C Babcock, Christina R Mikulka, Bing Wang, Sanjay Chandriani, Sundeep Chandra, Bryan K Yip

Sci Rep· July 2021

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Utility of Zwolle Risk Score in Guiding Low-Risk STEMI Discharge.
Teik Wen Lim, Tahiya Syeda Karim, Melinda Fernando, Joaud Haydar, Rachel Lightowler, Bryan Yip

Heart Lung Circ· April 2021

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Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B.
Anita Grover, Danielle Crippen-Harmon, Lacey Nave, Jon Vincelette, Jill C M Wait, Bryan K Yip

Drug Deliv Transl Res· April 2020

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Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target.
Yedda Li, Yue Xu, Bruno A Benitez, Murtaza S Nagree, Joshua T Dearborn, Bryan K Yip

Proc Natl Acad Sci U S A· October 2019

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BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesis.
Gouri Yogalingam, Amanda R Luu, Heather Prill, Melanie J Lo, Bryan Yip

PLoS One· September 2019

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Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type B.
Heather Prill, Amanda Luu, Bryan Yip, John Holtzinger, Melanie J Lo

Mol Ther Methods Clin Dev· September 2019

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In-hospital 'CODE STEMI' improves door-to-balloon time in patients undergoing primary percutaneous coronary intervention.
Ji Quan Koh, David C Tong, Rumes Sriamareswaran, Allysha Yeap, Bryan Yip

Emerg Med Australas· April 2018

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Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice.
Mika Aoyagi-Scharber, Danielle Crippen-Harmon, Roger Lawrence, Jon Vincelette, Gouri Yogalingam, Bryan K Yip

Mol Ther Methods Clin Dev· September 2017

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Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB.
Shih-Hsin Kan, Mika Aoyagi-Scharber, Steven Q Le, Jon Vincelette, Kazuhiro Ohmi, Bryan K Yip

Proc Natl Acad Sci U S A· October 2014

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Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinone.
Mika Aoyagi-Scharber, Anna S Gardberg, Bryan K Yip, Bing Wang, Yuqiao Shen

Acta Crystallogr F Struct Biol Commun· September 2014

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