Publications by authors named "Bryson Rast"

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The discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors.
Alex J Buckmelter, Li Ren, Ellen R Laird, Bryson Rast, Greg Miknis

Bioorg Med Chem Lett· February 2011

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Non-oxime inhibitors of B-Raf(V600E) kinase.
Li Ren, Steve Wenglowsky, Greg Miknis, Bryson Rast, Alex J Buckmelter

Bioorg Med Chem Lett· February 2011

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Comparative structure-activity relationship studies of 1-(5-methylsulfonylpyrid-2-yl)-5-alkyl and (hetero)aryl triazoles and pyrazoles in canine COX inhibition.
Subas M Sakya, Andrei Shavnya, Hengmiao Cheng, Chao Li, Bryson Rast

Bioorg Med Chem Lett· February 2008

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5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile.
Subas M Sakya, Xinjun Hou, Martha L Minich, Bryson Rast, Andrei Shavnya

Bioorg Med Chem Lett· February 2007

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5-Heteroatom-substituted pyrazoles as canine COX-2 inhibitors: Part 2. Structure-activity relationship studies of 5-alkylethers and 5-thioethers.
Subas M Sakya, Hengmiao Cheng, Kristin M Lundy Demello, Andrei Shavnya, Martha L Minich, Bryson Rast

Bioorg Med Chem Lett· March 2006

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5-heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure-activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog.
Subas M Sakya, Kristin M Lundy DeMello, Martha L Minich, Bryson Rast, Andrei Shavnya

Bioorg Med Chem Lett· January 2006

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Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine.
Jin Li, Kristin M Lundy DeMello, Henry Cheng, Subas M Sakya, Brian S Bronk, Bryson Rast

Bioorg Med Chem Lett· January 2004

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