Publications by authors named "Cagdas Tazearslan"

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Ligand-specific regulation of a binary enhancer code dictating cellular senescence.
Thomas Suter, Meyer J Friedman, Cagdas Tazearslan, Daria Merkurjev, Kenny Ohgi

Proc Natl Acad Sci U S A· June 2025

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Clinical and analytical validation of a combined RNA and DNA exome assay across a large tumor cohort.
Anastasiya Yudina, Cagdas Tazearslan, Artur Baisangurov, Ekaterina Nuzhdina, Kelley Lauziere

Commun Med (Lond)· June 2025

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Comprehensive peripheral blood immunoprofiling reveals five immunotypes with immunotherapy response characteristics in patients with cancer.
Daniiar Dyikanov, Aleksandr Zaitsev, Tatiana Vasileva, Iris Wang, Arseniy A Sokolov, Cagdas Tazearslan

Cancer Cell· May 2024

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In vitro heterochronic parabiosis identifies pigment epithelium-derived factor as a systemic mediator of rejuvenation by young blood.
Xizhe Wang, Cagdas Tazearslan, Seungsoo Kim, Qinghua Guo, Daniela Contreras

bioRxiv· May 2024

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Procrustes is a machine-learning approach that removes cross-platform batch effects from clinical RNA sequencing data.
Nikita Kotlov, Kirill Shaposhnikov, Cagdas Tazearslan, Madison Chasse, Artur Baisangurov

Commun Biol· March 2024

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Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of p16.
Yizhou Zhu, Cagdas Tazearslan, Michael G Rosenfeld, Andras Fiser, Yousin Suh

Aging Cell· September 2023

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The regulation of Insulin/IGF-1 signaling by miR-142-3p associated with human longevity.
Xifan Wang, Hwa Jin Jung, Brandon Milholland, Jinhua Cui, Cagdas Tazearslan

bioRxiv· May 2023

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Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of .
Yizhou Zhu, Cagdas Tazearslan, Michael G Rosenfeld, Andras Fiser, Yousin Suh

bioRxiv· May 2023

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Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes.
Aleksandr Zaitsev, Maksim Chelushkin, Daniiar Dyikanov, Ilya Cheremushkin, Boris Shpak, Cagdas Tazearslan

Cancer Cell· August 2022

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Molecular characterization of precise in vivo targeted gene integration in human cells using AAVHSC15.
Huei-Mei Chen, Rachel Resendes, Azita Ghodssi, Danielle Sookiasian, Michael Tian, Cagdas Tazearslan

PLoS One· August 2020

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Age- and Tissue-Specific Expression of Senescence Biomarkers in Mice.
Adam D Hudgins, Cagdas Tazearslan, Archana Tare, Yizhou Zhu, Derek Huffman

Front Genet· February 2018

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Challenges and progress in interpretation of non-coding genetic variants associated with human disease.
Yizhou Zhu, Cagdas Tazearslan, Yousin Suh

Exp Biol Med (Maywood)· July 2017

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LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control.
Jianxun Wang, Francesca Telese, Yuliang Tan, Wenbo Li, Chunyu Jin, Cagdas Tazearslan

Nat Neurosci· September 2015

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Rec-8 dimorphism affects longevity, stress resistance and X-chromosome nondisjunction in C. elegans, and replicative lifespan in S. cerevisiae.
Srinivas Ayyadevara, Cagdas Tazearslan, Ramani Alla, James C Jiang, S Michal Jazwinski

Front Genet· August 2014

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Septin 9 amplification and isoform-specific expression in peritumoral and tumor breast tissue.
Diana Connolly, Hien G Hoang, Esther Adler, Cagdas Tazearslan, Nichelle Simmons

Biol Chem· February 2014

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Discovery of functional gene variants associated with human longevity: opportunities and challenges.
Cagdas Tazearslan, Miook Cho, Yousin Suh

J Gerontol A Biol Sci Med Sci· April 2012

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Impaired IGF1R signaling in cells expressing longevity-associated human IGF1R alleles.
Cagdas Tazearslan, Jing Huang, Nir Barzilai, Yousin Suh

Aging Cell· June 2011

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Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants.
Robert J Shmookler Reis, Lulu Xu, Hoonyong Lee, Minho Chae, John J Thaden, Cagdas Tazearslan

Aging (Albany NY)· February 2011

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Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespan.
Srinivas Ayyadevara, Cagdaş Tazearslan, Puneet Bharill, Ramani Alla, Eric Siegel

Aging Cell· December 2009

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Extreme-longevity mutations orchestrate silencing of multiple signaling pathways.
Robert J Shmookler Reis, Puneet Bharill, Cagdas Tazearslan, Srinivas Ayyadevara

Biochim Biophys Acta· October 2009

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Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance.
Cagdaş Tazearslan, Srinivas Ayyadevara, Puneet Bharill, Robert J Shmookler Reis

PLoS Genet· April 2009

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