Publications by authors named "Cai Read"

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G protein signaling-biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists.
Edward L Stahl, Cullen L Schmid, Agnes Acevedo-Canabal, Cai Read, Travis W Grim

Proc Natl Acad Sci U S A· November 2021

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The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis and Induces Vasodilatation Without Desensitisation .
Cai Read, Duuamene Nyimanu, Peiran Yang, Rhoda E Kuc, Thomas L Williams

Front Pharmacol· January 2021

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Apelin peptides linked to anti-serum albumin domain antibodies retain affinity in vitro and are efficacious receptor agonists in vivo.
Cai Read, Peiran Yang, Rhoda E Kuc, Duuamene Nyimanu, Thomas L Williams

Basic Clin Pharmacol Toxicol· June 2020

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International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand.
Cai Read, Duuamene Nyimanu, Thomas L Williams, David J Huggins, Petra Sulentic

Pharmacol Rev· October 2019

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A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension.
Peiran Yang, Cai Read, Rhoda E Kuc, Duuamene Nyimanu, Thomas L Williams

Br J Pharmacol· May 2019

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Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension.
Benjamin E Garfield, Alexi Crosby, Dongmin Shao, Peiran Yang, Cai Read

Thorax· February 2019

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Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.
Peiran Yang, Cai Read, Rhoda E Kuc, Guido Buonincontri, Mark Southwood

Circulation· March 2017

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Chemerin Elicits Potent Constrictor Actions via Chemokine-Like Receptor 1 (CMKLR1), not G-Protein-Coupled Receptor 1 (GPR1), in Human and Rat Vasculature.
Amanda J Kennedy, Peiran Yang, Cai Read, Rhoda E Kuc, Lucy Yang

J Am Heart Assoc· October 2016

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Cardiac action of the first G protein biased small molecule apelin agonist.
Cai Read, Christopher M Fitzpatrick, Peiran Yang, Rhoda E Kuc, Janet J Maguire

Biochem Pharmacol· September 2016

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