Publications by authors named "Caleb J Bashor"

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Engineering synthetic phosphorylation signaling networks in human cells.
Xiaoyu Yang, Jason W Rocks, Kaiyi Jiang, Andrew J Walters, Kshitij Rai, Jing Liu, Jason Nguyen, Scott D Olson, Pankaj Mehta, James J Collins

Science· January 2025

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Integrating synthetic biology to understand and engineer the heart, lung, blood, and sleep systems.
Elliot L Chaikof, Jichao Chen, Martha U Gillette, Laurie A Boyer, Tara L Deans, Caleb J Bashor

Cell Syst· December 2025

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Ultra-high throughput mapping of genetic design space.
Kshitij Rai, Ronan W O'Connell, Trenton C Piepergerdes, Yiduo Wang, Lucas B C Brown, Caleb J Bashor

bioRxiv· May 2025

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Enhancing the safety and efficacy of cell therapy with programmed sense-and-respond function.
Andrew J Walters, Xiaoyu Yang, Scott D Olson, Caleb J Bashor

Clin Transl Med· May 2025

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Engineering synthetic phosphorylation signaling networks in human cells.
Xiaoyu Yang, Jason W Rocks, Kaiyi Jiang, Andrew J Walters, Kshitij Rai, Caleb J Bashor

bioRxiv· November 2023

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Cooperative assembly confers regulatory specificity and long-term genetic circuit stability.
Meghan D J Bragdon, Nikit Patel, James Chuang, Ethan Levien, Caleb J Bashor

Cell· August 2023

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Tumor-associated macrophages induce inflammation and drug resistance in a mechanically tunable engineered model of osteosarcoma.
Letitia K Chim, Isabelle L Williams, Caleb J Bashor, Antonios G Mikos

Biomaterials· May 2023

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pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells.
Payam E Farahani, Xiaoyu Yang, Emily V Mesev, Kaylan A Fomby, Ellen H Brumbaugh-Reed, Caleb J Bashor

Elife· May 2023

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Engineering the next generation of cell-based therapeutics.
Caleb J Bashor, Isaac B Hilton, Hozefa Bandukwala, Devyn M Smith, Omid Veiseh

Nat Rev Drug Discov· September 2022

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Assessing the impact of silicon nanowires on bacterial transformation and viability of .
Michele Becce, Anna Klöckner, Stuart G Higgins, Jelle Penders, Daniel Hachim, Caleb J Bashor

J Mater Chem B· June 2021

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Mammalian signaling circuits from bacterial parts.
Xiaoyu Yang, John Her, Caleb J Bashor

Nat Chem Biol· February 2020

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Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies.
Caleb J Bashor, Nikit Patel, Sandeep Choubey, Ali Beyzavi, Jané Kondev

Science· May 2019

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Designing Automated, High-throughput, Continuous Cell Growth Experiments Using eVOLVER.
Zachary J Heins, Christopher P Mancuso, Szilvia Kiriakov, Brandon G Wong, Caleb J Bashor

J Vis Exp· May 2019

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The Least Mating Pathway: Synthetically Refactoring a Familiar Signaling System for New Applications.
Ronan W O'Connell, Caleb J Bashor

Cell· April 2019

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Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER.
Brandon G Wong, Christopher P Mancuso, Szilvia Kiriakov, Caleb J Bashor, Ahmad S Khalil

Nat Biotechnol· August 2018

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Understanding Biological Regulation Through Synthetic Biology.
Caleb J Bashor, James J Collins

Annu Rev Biophys· May 2018

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Engineering dynamical control of cell fate switching using synthetic phospho-regulons.
Russell M Gordley, Reid E Williams, Caleb J Bashor, Jared E Toettcher, Shude Yan

Proc Natl Acad Sci U S A· November 2016

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'Deadman' and 'Passcode' microbial kill switches for bacterial containment.
Clement T Y Chan, Jeong Wook Lee, D Ewen Cameron, Caleb J Bashor, James J Collins

Nat Chem Biol· February 2016

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Using targeted chromatin regulators to engineer combinatorial and spatial transcriptional regulation.
Albert J Keung, Caleb J Bashor, Szilvia Kiriakov, James J Collins, Ahmad S Khalil

Cell· July 2014

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A brief history of synthetic biology.
D Ewen Cameron, Caleb J Bashor, James J Collins

Nat Rev Microbiol· May 2014

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Insulating gene circuits from context by RNA processing.
Caleb J Bashor, James J Collins

Nat Biotechnol· November 2012

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A synthetic biology framework for programming eukaryotic transcription functions.
Ahmad S Khalil, Timothy K Lu, Caleb J Bashor, Cherie L Ramirez, Nora C Pyenson

Cell· August 2012

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SYNZIP protein interaction toolbox: in vitro and in vivo specifications of heterospecific coiled-coil interaction domains.
Kenneth Evan Thompson, Caleb J Bashor, Wendell A Lim, Amy E Keating

ACS Synth Biol· April 2012

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Rewiring cells: synthetic biology as a tool to interrogate the organizational principles of living systems.
Caleb J Bashor, Andrew A Horwitz, Sergio G Peisajovich, Wendell A Lim

Annu Rev Biophys· July 2010

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Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics.
Caleb J Bashor, Noah C Helman, Shude Yan, Wendell A Lim

Science· March 2008

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