Publications by authors named "Caleb Lord"

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Leveraging toxicogenomics in a weight of evidence approach to demonstrate a CAR-mediated mode of action for cyclobutrifluram-related mouse liver tumors.
Fang Zhang, Caleb C Lord, Aniko Kende, David E Cowie, Liam B Doonan

Toxicol Sci· September 2025

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Fatty Acid Synthase regulates glucose and energy homeostasis via POMC neurons and adrenergic signals.
Luis Leon-Mercado, Yanbin Dong, Bandy Chen, Arely Tinajero, Caleb C Lord

Mol Metab· August 2025

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Assessing human carcinogenicity risk of agrochemicals without the rodent cancer bioassay.
Amber Goetz, Natalia Ryan, Alaina Sauve-Ciencewicki, Caleb C Lord, Gina M Hilton

Front Toxicol· June 2024

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Gα-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents.
Eun-Seon Yoo, Li Li, Lin Jia, Caleb C Lord, Charlotte E Lee

Cell Rep· November 2021

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Acyl-ghrelin Is Permissive for the Normal Counterregulatory Response to Insulin-Induced Hypoglycemia.
Kripa Shankar, Deepali Gupta, Bharath K Mani, Brianna G Findley, Caleb C Lord

Diabetes· February 2020

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Ghrelin Receptor Agonist Rescues Excess Neonatal Mortality in a Prader-Willi Syndrome Mouse Model.
Juan A Rodriguez, Emily C Bruggeman, Bharath K Mani, Sherri Osborne-Lawrence, Caleb C Lord

Endocrinology· December 2018

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Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease.
Lin Jia, Xiuli Chang, Shuwen Qian, Chen Liu, Caleb C Lord

Mol Metab· August 2018

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POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels.
Alexandre Caron, Heather M Dungan Lemko, Carlos M Castorena, Teppei Fujikawa, Syann Lee, Caleb C Lord

Elife· March 2018

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The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C.
Caleb C Lord, Steven C Wyler, Rong Wan, Carlos M Castorena, Newaz Ahmed

J Clin Invest· September 2017

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Serotonergic Control of Metabolic Homeostasis.
Steven C Wyler, Caleb C Lord, Syann Lee, Joel K Elmquist, Chen Liu

Front Cell Neurosci· September 2017

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Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation.
Caleb C Lord, Daniel Ferguson, Gwynneth Thomas, Amanda L Brown, Rebecca C Schugar

Cell Rep· July 2016

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Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity.
Renate Schreiber, Peter Hofer, Ulrike Taschler, Peter J Voshol, Gerald N Rechberger, Caleb C Lord

Proc Natl Acad Sci U S A· November 2015

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Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis.
Madeleine Goeritzer, Stefanie Schlager, Branislav Radovic, Corina T Madreiter, Silvia Rainer, Caleb C Lord

J Lipid Res· December 2014

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The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome.
Gwynneth Thomas, Jenna L Betters, Caleb C Lord, Amanda L Brown, Stephanie Marshall

Cell Rep· October 2013

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Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice.
Kanwardeep S Bura, Caleb Lord, Stephanie Marshall, Allison McDaniel, Gwyn Thomas

J Lipid Res· June 2013

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Mammalian alpha beta hydrolase domain (ABHD) proteins: Lipid metabolizing enzymes at the interface of cell signaling and energy metabolism.
Caleb C Lord, Gwynneth Thomas, J Mark Brown

Biochim Biophys Acta· April 2013

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CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action.
Caleb C Lord, Jenna L Betters, Pavlina T Ivanova, Stephen B Milne, David S Myers

Diabetes· February 2012

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Distinct roles for alpha-beta hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling.
Caleb C Lord, J Mark Brown

Adipocyte· January 2012

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Adipose-selective overexpression of ABHD5/CGI-58 does not increase lipolysis or protect against diet-induced obesity.
Jorge M Caviglia, Jenna L Betters, Dianne-Helerie Dapito, Caleb C Lord, Sean Sullivan

J Lipid Res· November 2011

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CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance.
J Mark Brown, Jenna L Betters, Caleb Lord, Yinyan Ma, Xianlin Han

J Lipid Res· November 2010

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Biliary sterol secretion is not required for macrophage reverse cholesterol transport.
Ryan E Temel, Janet K Sawyer, Liqing Yu, Caleb Lord, Chiara Degirolamo

Cell Metab· July 2010

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Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis.
J Mark Brown, Soonkyu Chung, Janet K Sawyer, Chiara Degirolamo, Heather M Alger, Caleb Lord

Arterioscler Thromb Vasc Biol· January 2010

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