Publications by authors named "Calogera M Simonaro"

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Endocannabinoid receptor 2 is a potential biomarker and therapeutic target for the lysosomal storage disorders.
Calogera M Simonaro, Makiko Yasuda, Edward H Schuchman

J Inherit Metab Dis· January 2025

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Acid Ceramidase Protects Against Hepatic Ischemia/Reperfusion Injury by Modulating Sphingolipid Metabolism and Reducing Inflammation and Oxidative Stress.
Yuan Jiang, Xingxuan He, Calogera M Simonaro, Bin Yi, Edward H Schuchman

Front Cell Dev Biol· May 2021

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New paradigms for the treatment of lysosomal storage diseases: targeting the endocannabinoid system as a therapeutic strategy.
Edward H Schuchman, Maria D Ledesma, Calogera M Simonaro

Orphanet J Rare Dis· March 2021

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Safety Study of Sodium Pentosan Polysulfate for Adult Patients with Mucopolysaccharidosis Type II.
Kenji Orii, Alaena Lim, Shunji Tomatsu, Molly Stapleton, Yasuyuki Suzuki, Calogera M Simonaro

Diagnostics (Basel)· December 2019

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Pentosan Polysulfate Treatment of Mucopolysaccharidosis Type IIIA Mice.
Ningning Guo, Victor DeAngelis, Changzhi Zhu, Edward H Schuchman, Calogera M Simonaro

JIMD Rep· April 2018

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Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice.
Xingxuan He, Shaalee Dworski, Changzhi Zhu, Victor DeAngelis, Alex Solyom, Calogera M Simonaro

BBA Clin· June 2017

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Treatment with pentosan polysulphate in patients with MPS I: results from an open label, randomized, monocentric phase II study.
Julia B Hennermann, Seyfullah Gökce, Alexander Solyom, Eugen Mengel, Edward H Schuchman, Calogera M Simonaro

J Inherit Metab Dis· November 2016

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Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs.
Calogera M Simonaro, Shunji Tomatsu, Tracy Sikora, Francyne Kubaski, Michael Frohbergh

PLoS One· August 2016

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Dose responsive effects of subcutaneous pentosan polysulfate injection in mucopolysaccharidosis type VI rats and comparison to oral treatment.
Michael Frohbergh, Yi Ge, Fanli Meng, Nesrin Karabul, Alexander Solyom, Calogera M Simonaro

PLoS One· February 2015

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Intra-articular enzyme replacement therapy with rhIDUA is safe, well-tolerated, and reduces articular GAG storage in the canine model of mucopolysaccharidosis type I.
Raymond Y Wang, Afshin Aminian, Michael F McEntee, Shih-Hsin Kan, Calogera M Simonaro

Mol Genet Metab· August 2014

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Acid ceramidase maintains the chondrogenic phenotype of expanded primary chondrocytes and improves the chondrogenic differentiation of bone marrow-derived mesenchymal stem cells.
Calogera M Simonaro, Sylvain Sachot, Yi Ge, Xingxuan He, Victor A Deangelis

PLoS One· November 2013

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Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses.
Edward H Schuchman, Yi Ge, Alon Lai, Yury Borisov, Meghan Faillace, Calogera M Simonaro

PLoS One· July 2013

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The genetics of sphingolipid hydrolases and sphingolipid storage diseases.
Edward H Schuchman, Calogera M Simonaro

Handb Exp Pharmacol· July 2013

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Systemic ceramide accumulation leads to severe and varied pathological consequences.
Abdulfatah M Alayoubi, James C M Wang, Bryan C Y Au, Stéphane Carpentier, Virginie Garcia, Calogera M Simonaro

EMBO Mol Med· June 2013

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Structural, compositional, and biomechanical alterations of the lumbar spine in rats with mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome).
Alon Lai, Calogera M Simonaro, Edward H Schuchman, Yi Ge, Damien M Laudier

J Orthop Res· April 2013

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Two siblings with Niemann-Pick disease (NPD) type B: clinical findings and novel mutations of the acid sphingomyelinase gene.
Zoran Gucev, Velibor Tasic, Nada Pop-Jordanova, Aleksandra Jancevska, Calogera M Simonaro

Indian J Pediatr· February 2013

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Cartilage and chondrocyte pathology in the mucopolysaccharidoses: The role of glycosaminoglycan-mediated inflammation.
Calogera M Simonaro

J Pediatr Rehabil Med· October 2012

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Anti-TNF-alpha therapy enhances the effects of enzyme replacement therapy in rats with mucopolysaccharidosis type VI.
Efrat Eliyahu, Theodore Wolfson, Yi Ge, Karl J Jepsen, Edward H Schuchman, Calogera M Simonaro

PLoS One· January 2012

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Identification and characterization of eight novel SMPD1 mutations causing types A and B Niemann-Pick disease.
Jonathan P Desnick, Jungmin Kim, Xingxuan He, Melissa P Wasserstein, Calogera M Simonaro

Mol Med· November 2010

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Involvement of the Toll-like receptor 4 pathway and use of TNF-alpha antagonists for treatment of the mucopolysaccharidoses.
Calogera M Simonaro, Yi Ge, Efrat Eliyahu, Xingxuan He, Karl J Jepsen

Proc Natl Acad Sci U S A· January 2010

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Mechanism of glycosaminoglycan-mediated bone and joint disease: implications for the mucopolysaccharidoses and other connective tissue diseases.
Calogera M Simonaro, Marina D'Angelo, Xingxuan He, Efrat Eliyahu, Nataly Shtraizent

Am J Pathol· January 2008

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Imprinting at the SMPD1 locus: implications for acid sphingomyelinase-deficient Niemann-Pick disease.
Calogera M Simonaro, Jae-Ho Park, Efrat Eliyahu, Nataly Shtraizent, Margaret M McGovern

Am J Hum Genet· May 2006

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Joint and bone disease in mucopolysaccharidoses VI and VII: identification of new therapeutic targets and biomarkers using animal models.
Calogera M Simonaro, Marina D'Angelo, Mark E Haskins, Edward H Schuchman

Pediatr Res· May 2005

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The demographics and distribution of type B Niemann-Pick disease: novel mutations lead to new genotype/phenotype correlations.
Calogera M Simonaro, Robert J Desnick, Margaret M McGovern, Melissa P Wasserstein, Edward H Schuchman

Am J Hum Genet· December 2002

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Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes.
Chi-Ming Li, Jae-Ho Park, Calogera M Simonaro, Xingxuan He, Ronald E Gordon

Genomics· February 2002

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