Publications by authors named "Calvin Harley"

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Analytical Validation of Relative Average Telomere Length Measurement in a Clinical Laboratory Environment.
Marsha N Blauwkamp, Clare L Fasching, Jue Lin, Karl Guegler, Evangelos Hytopoulos, Calvin B Harley

J Appl Lab Med· July 2017

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A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study.
Laura Salvador, Gunasekaran Singaravelu, Calvin B Harley, Peter Flom, Anitha Suram

Rejuvenation Res· December 2016

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Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study.
Coad Thomas Dow, Calvin B Harley

Clin Ophthalmol· February 2016

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Cycloastragenol is a potent telomerase activator in neuronal cells: implications for depression management.
Fanny C F Ip, Yu Pong Ng, H J An, Ying Dai, Hai Hong Pang, Calvin B Harley

Neurosignals· October 2015

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A natural product telomerase activator as part of a health maintenance program: metabolic and cardiovascular response.
Calvin B Harley, Weimin Liu, Peter L Flom, Joseph M Raffaele

Rejuvenation Res· October 2013

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A novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosis.
Claude Jourdan Le Saux, Philip Davy, Christopher Brampton, Seema S Ahuja, Steven Fauce, Calvin B Harley

PLoS One· September 2013

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Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types.
Lisa Y Yung, Wing See Lam, Maurice K C Ho, Yueqing Hu, Fanny C F Ip, Calvin B Harley

Planta Med· January 2012

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The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence.
Bruno Bernardes de Jesus, Kerstin Schneeberger, Elsa Vera, Agueda Tejera, Calvin B Harley

Aging Cell· August 2011

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In vitro intestinal absorption and first-pass intestinal and hepatic metabolism of cycloastragenol, a potent small molecule telomerase activator.
Jing Zhu, Stephanie Lee, Maurice K C Ho, Yueqing Hu, Haihong Pang, Calvin B Harley

Drug Metab Pharmacokinet· April 2011

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A natural product telomerase activator as part of a health maintenance program.
Calvin B Harley, Weimin Liu, Maria Blasco, Elsa Vera, William H Andrews

Rejuvenation Res· February 2011

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Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition.
Pedro Castelo-Branco, Cindy Zhang, Tatiana Lipman, Mayumi Fujitani, Loen Hansford, Calvin B Harley

Clin Cancer Res· January 2011

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The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines.
Immanual Joseph, Robert Tressler, Ekaterina Bassett, Calvin Harley, Christen M Buseman

Cancer Res· November 2010

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Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms.
Sarah K Brennan, Qiuju Wang, Robert Tressler, Calvin Harley, Ning Go

PLoS One· September 2010

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Measurement of telomere length by the Southern blot analysis of terminal restriction fragment lengths.
Masayuki Kimura, Rivka C Stone, Steven C Hunt, Joan Skurnick, Xiaobin Lu, Calvin B Harley

Nat Protoc· September 2010

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Imetelstat (GRN163L)--telomerase-based cancer therapy.
Alexander Röth, Calvin B Harley, Gabriela M Baerlocher

Recent Results Cancer Res· March 2010

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Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.
Steven Russell Fauce, Beth D Jamieson, Allison C Chin, Ronald T Mitsuyasu, Stan T Parish, Calvin B Harley

J Immunol· November 2008

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Oligonucleotide conjugate GRN163L targeting human telomerase as potential anticancer and antimetastatic agent.
Sergei M Gryaznov, Shalmica Jackson, Gunnur Dikmen, Calvin Harley, Brittney-Shea Herbert

Nucleosides Nucleotides Nucleic Acids· March 2008

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Telomerase and cancer therapeutics.
Calvin B Harley

Nat Rev Cancer· March 2008

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Adenoviral human telomerase reverse transcriptase dramatically improves ischemic wound healing without detrimental immune response in an aged rabbit model.
Jon E Mogford, W Robert Liu, Russell Reid, Choy-Pik Chiu, Hakim Said, Calvin B Harley

Hum Gene Ther· June 2006

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Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.
Meta W Djojosubroto, Allison C Chin, Ning Go, Sonja Schaetzlein, Michael P Manns, Calvin B Harley

Hepatology· November 2005

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Lipid modification of GRN163, an N3'-->P5' thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition.
Brittney-Shea Herbert, Ginelle C Gellert, Amelia Hochreiter, Krisztina Pongracz, Woodring E Wright, Calvin B Harley

Oncogene· August 2005

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Telomerase therapeutics for degenerative diseases.
Calvin B Harley

Curr Mol Med· March 2005

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Telomere length assessment in tissue sections by quantitative FISH: image analysis algorithms.
Jacintha N O'Sullivan, Jennifer C Finley, Rosa-ana Risques, Wen-Tang Shen, Katherine A Gollahon, Calvin B Harley

Cytometry A· April 2004

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The aging factor in health and disease: the promise of basic research on aging.
Robert N Butler, Huber R Warner, T Franklin Williams, Steven N Austad, Jacob A Brody, Calvin B Harley

Aging Clin Exp Res· April 2004

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Oligonucleotide N3' --> P5' thio-phosphoramidate telomerase template antagonists as potential anticancer agents.
Sergei Gryaznov, Akira Asai, Yuko Oshima, Yoshihiro Yamamoto, Krisztina Pongracz, Calvin Harley

Nucleosides Nucleotides Nucleic Acids· December 2003

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